VOLPINI, Rosaria
 Distribuzione geografica
Continente #
NA - Nord America 20.205
EU - Europa 9.043
AS - Asia 7.128
SA - Sud America 971
Continente sconosciuto - Info sul continente non disponibili 529
AF - Africa 259
OC - Oceania 16
Totale 38.151
Nazione #
US - Stati Uniti d'America 19.554
CN - Cina 2.907
SG - Singapore 2.170
RU - Federazione Russa 1.958
PL - Polonia 1.552
IT - Italia 1.494
DE - Germania 975
BR - Brasile 804
GB - Regno Unito 626
HK - Hong Kong 566
UA - Ucraina 539
CA - Canada 534
FR - Francia 525
SE - Svezia 524
VN - Vietnam 486
FI - Finlandia 365
KR - Corea 230
TR - Turchia 219
ZA - Sudafrica 181
IE - Irlanda 137
IN - India 120
JP - Giappone 103
MX - Messico 68
NL - Olanda 66
AR - Argentina 57
BE - Belgio 49
ES - Italia 49
EU - Europa 49
BD - Bangladesh 48
CZ - Repubblica Ceca 37
IQ - Iraq 36
IR - Iran 33
AT - Austria 28
EC - Ecuador 28
PK - Pakistan 25
VE - Venezuela 22
ID - Indonesia 20
CO - Colombia 19
RO - Romania 18
UZ - Uzbekistan 18
AE - Emirati Arabi Uniti 17
TW - Taiwan 17
LT - Lituania 16
CH - Svizzera 15
SA - Arabia Saudita 15
KE - Kenya 14
CL - Cile 13
IL - Israele 13
TN - Tunisia 13
JM - Giamaica 12
JO - Giordania 12
PY - Paraguay 12
AU - Australia 11
MA - Marocco 11
RS - Serbia 11
AZ - Azerbaigian 9
DZ - Algeria 9
PE - Perù 9
PH - Filippine 9
EG - Egitto 8
NP - Nepal 8
CR - Costa Rica 7
DK - Danimarca 7
LB - Libano 7
BG - Bulgaria 6
MY - Malesia 6
TH - Thailandia 6
AM - Armenia 5
CI - Costa d'Avorio 5
GR - Grecia 5
GT - Guatemala 5
HN - Honduras 5
LV - Lettonia 5
PA - Panama 5
AL - Albania 4
BO - Bolivia 4
GE - Georgia 4
HR - Croazia 4
KZ - Kazakistan 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
TT - Trinidad e Tobago 4
BY - Bielorussia 3
EE - Estonia 3
ET - Etiopia 3
KH - Cambogia 3
LU - Lussemburgo 3
NI - Nicaragua 3
NO - Norvegia 3
SK - Slovacchia (Repubblica Slovacca) 3
UY - Uruguay 3
BB - Barbados 2
CM - Camerun 2
DO - Repubblica Dominicana 2
GA - Gabon 2
HU - Ungheria 2
KW - Kuwait 2
MT - Malta 2
MU - Mauritius 2
OM - Oman 2
Totale 37.644
Città #
Fairfield 1.763
Ashburn 1.609
Woodbridge 1.493
Warsaw 1.349
Jacksonville 1.324
Singapore 1.085
Houston 1.070
Chandler 1.053
San Jose 929
Council Bluffs 786
Seattle 783
Wilmington 756
Ann Arbor 647
Cambridge 605
Boardman 566
Dallas 566
Hong Kong 537
Nanjing 463
Beijing 461
Toronto 335
The Dalles 279
Los Angeles 271
Camerino 252
New York 205
Seoul 205
San Mateo 199
Columbus 190
Tongling 189
Dearborn 188
Kraków 185
Princeton 183
Lawrence 180
Düsseldorf 175
Helsinki 173
Istanbul 168
Lauterbourg 162
Johannesburg 160
Ogden 147
Ho Chi Minh City 145
Dublin 136
Buffalo 134
London 130
Lachine 128
Santa Clara 128
Moscow 124
Nanchang 123
Hanoi 112
Shanghai 106
Chicago 101
Guangzhou 97
Milan 93
Shenyang 91
São Paulo 91
Munich 88
Tianjin 87
San Diego 85
Tokyo 81
Frankfurt am Main 78
Kunming 74
Hebei 62
Jiaxing 56
Phoenix 55
Orem 54
Rome 52
Brussels 48
Edinburgh 46
Changsha 42
St Louis 41
Wuhan 40
Denver 39
Jinan 39
Redwood City 39
Ningbo 38
Atlanta 37
Centro 37
Hangzhou 37
Dong Ket 35
Stockholm 35
Manchester 34
Philadelphia 33
Trieste 33
Boston 32
San Francisco 32
Turku 31
Venezia 31
Brooklyn 30
Zhengzhou 30
Poplar 29
Verona 29
Chennai 28
Hefei 28
Mexico City 28
Rio de Janeiro 28
Salt Lake City 28
Ascoli Piceno 26
Montreal 26
Brno 25
Falls Church 25
Norwalk 25
Amsterdam 24
Totale 25.390
Nome #
1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies 652
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 461
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 412
Overview on Radiolabel-Free in Vitro Assays for GPCRs 407
Pharmacological characterization of the GPR17 receptor dual profile 402
GPR17 receptor modulators and their therapeutic implications: review of recent patents 393
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 390
The G Protein-Coupled Receptor GPR17: Overview and Update 375
2′,3′-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 368
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 360
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 337
Medicinal chemistry and pharmacology of A2B adenosine receptors 303
Adenine based acyclic-nucleotides as novel P2X3 receptor ligands 301
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 297
Synthesis and antitumor evaluation of bis aza-anthracene-9,10-diones and bis aza-anthrapyrazole-6-ones 294
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 288
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 281
Dual target strategy: Combining distinct non-dopaminergic treatments reduces neuronal cell loss and synergistically modulates l -DOPA-induced rotational behavior in a rodent model of Parkinson's disease 280
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 273
2-Aralkynyl and 2-Heteroalkynyl derivatives of Adenosine-5'-N-ethyluronamide as selective A2a adenosine receptor agonists 272
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 271
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 270
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 265
2-Substituted N-ethylcarboxamidoadenosine derivatives as high affinity agonists at human A(3) adenosine receptors 262
Approaches for designing and discovering purinergic drugs for gastrointestinal diseases 260
2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors 256
2-Alkynyl derivatives of Adenosine-5'-N-ethyluronamide (NECA): selective A2 adenosine receptor agonists with potent inhibitory activity on Platelet aggregation 253
3'-Deoxyribofuranose derivatives of 1-deaza and 3-deaza adenosine and their activity as adenosine deaminase inhibitors 252
Adenine and deazaadenine nucleoside and deoxynucleoside analogues: inhibition of viral replication of sheep MVV (in vitro model for HIV) and bovine BHV-1 251
A(2A) adenosine receptor agonists reduce both high-palatability and low-palatability food intake in female rats 250
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 250
9-ethyladenine derivatives as adenosine receptor antagonists: 2- and 8-substitution results in distinct selectivities 250
Biomarkers mapping of neuropathic pain in a nerve chronic constriction injury mice model 249
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 247
Human placenta cytidine deaminase: a zinc metalloprotein 242
Human cytidine deaminase: understanding the catalytic mechanism 242
Determination of ink photoinitiators in packaged beverages by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry 242
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 241
Isoenzymatic forms of human cytidine deaminase 240
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 240
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 240
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 238
Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs 237
Purine and deazapurine nucleosides: synthetic approaches, molecular modeling and biological activity 235
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 235
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 235
A(2A) Adenosine receptor and its modulators: overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and antagonists 229
2- And 8- alkynyladenosines: conformational studies and docking to human adenosine A(3) receptor can explain their different biological behavior 228
Adenosine deaminase: Functional implications and different classes of inhibitors 228
New sensible method to quantize the intestinal absorption of receptor ligands 228
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of 2-hydroxy-3-nonyl derivatives of azoles 226
Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation 226
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 224
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 224
Antiviral properties of deazaadenine nucleoside derivatives 223
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 222
2-Alkenyl and 2-alkyl derivatives of adenosine and adenosine-5'-N-ethyluronamide: different affinity and selectivity of E- and Z-diastereomers at A2A adenosine receptors 220
Antiviral activity of purine nucleoside analogs against bovine herpesvirus (BHV-1) and maedi visna virus (MVV) 220
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 220
CX3CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes. 217
"N-Cycloalkylalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists at the A1 adenosine receptor 216
Adenosine A(2A) receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease 215
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 215
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 214
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 213
Adenosine receptor modeling: what does the A2A crystal structure tell us? 212
2-substituted 5 '-N-methylcarboxamidoadenosine (MECA) derivatives as A(3) adenosine receptor ligands 209
Diazepinone nucleosides as inhibitors of cytidine deaminase 209
2- And 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosines receptors 209
Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor. 208
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family 208
2-phenylhydroxypropynyladenosine derivatives as high potent agonists at A(2B) adenosine receptor subtype 207
Purinergic Ligands as Potential Therapeutic Tools for the Treatment of Inflammation-Related Intestinal Diseases 206
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 205
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 205
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 204
Ring opening reactions: synthesis of AICAR analogs as potential antimetabolite agents 202
Pharmacological postconditioning of the rabbit heart with non-selective, A1, A2A and A3 adenosine receptor agonists 202
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 201
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 201
New 2,6,9-trisubstituted adenines as adenosine receptor antagonists: a preliminary SAR profile 200
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 197
2-ChloroATP exerts anti-tumoral actions not mediated by P2 receptors in neuronal and glial cells line 196
Chemical and pharmacological profile of selective adenosine receptor agonists 196
Synthesis and receptor affinity of polysubstituted adenosines 195
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 195
Unexpected synthesis of acyclic adenine nucleosides 194
Introduction of alkynyl chains on C-8 of adenosine led to very selective antagonists of the A(3) adenosine receptor 193
GPCRs as therapeutic targets: a view on adenosine receptors structure and functions, and molecular modeling support 193
Adenosine deaminase inhibitors: structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogs 192
A(2B) adenosine receptor agonists: synthesis and biological evaluation of 2-phenylhydroxypropynyladenosine and NECA derivatives 191
Potent and selective ligands for adenosine binding sites 191
[3H]HEMADO – a novel tritiated agonist selective for the human adenosine A(3) receptor 191
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 189
Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A1 and A2A adenosine receptors 189
Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease 189
A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable? 189
Amino-3,5-Dicyanopyridines Targeting the Adenosine Receptors Ranging from Pan Ligands to Combined A1/A2B Partial Agonists 188
9-Ethyladenine derivatives as adenosine receptor antagonists: 2- and 8-substitution result in distinct selectivities. 186
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 186
Totale 24.735
Categoria #
all - tutte 150.978
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 150.978


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.995 0 534 55 91 122 119 102 167 170 235 157 243
2022/20232.525 256 144 76 420 277 361 11 154 461 134 165 66
2023/20241.883 265 100 110 76 87 173 87 104 222 62 49 548
2024/20256.213 231 140 527 295 200 361 709 1.540 518 436 382 874
2025/20269.009 538 524 1.072 1.240 984 701 1.487 581 511 580 482 309
2026/2027854 612 242 0 0 0 0 0 0 0 0 0 0
Totale 38.151