BUCCIONI, Michela
 Distribuzione geografica
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Continente #
NA - Nord America 9.011
EU - Europa 4.073
AS - Asia 1.569
Continente sconosciuto - Info sul continente non disponibili 31
SA - Sud America 26
AF - Africa 9
OC - Oceania 6
Totale 14.725
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Nazione #
US - Stati Uniti d'America 8.754
PL - Polonia 1.225
CN - Cina 1.112
IT - Italia 826
DE - Germania 578
UA - Ucraina 321
GB - Regno Unito 262
SE - Svezia 256
CA - Canada 252
FR - Francia 224
SG - Singapore 223
FI - Finlandia 152
TR - Turchia 100
IE - Irlanda 79
BE - Belgio 45
EU - Europa 31
VN - Vietnam 31
KR - Corea 26
CZ - Repubblica Ceca 21
RU - Federazione Russa 18
IN - India 17
BR - Brasile 16
NL - Olanda 16
RO - Romania 15
HK - Hong Kong 14
IR - Iran 9
JP - Giappone 7
AT - Austria 5
CH - Svizzera 5
DK - Danimarca 5
AR - Argentina 4
AU - Australia 4
LB - Libano 4
PK - Pakistan 4
RS - Serbia 4
CL - Cile 3
ES - Italia 3
GR - Grecia 3
MX - Messico 3
NO - Norvegia 3
TW - Taiwan 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
BY - Bielorussia 2
DZ - Algeria 2
EC - Ecuador 2
GE - Georgia 2
IL - Israele 2
MA - Marocco 2
TN - Tunisia 2
AM - Armenia 1
AS - Samoa Americane 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CM - Camerun 1
HN - Honduras 1
HU - Ungheria 1
IQ - Iraq 1
JO - Giordania 1
KH - Cambogia 1
LK - Sri Lanka 1
MY - Malesia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 14.725
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Città #
Fairfield 1.156
Warsaw 994
Woodbridge 977
Jacksonville 759
Houston 624
Chandler 592
Ashburn 569
Seattle 475
Wilmington 465
Ann Arbor 443
Cambridge 417
Boardman 338
Kraków 229
Nanjing 211
Camerino 200
Toronto 184
Singapore 141
San Mateo 112
Lawrence 107
Princeton 107
Dearborn 105
Ogden 96
Istanbul 89
Beijing 85
Columbus 85
Nanchang 84
Dublin 78
Düsseldorf 74
Helsinki 69
Shanghai 69
San Diego 68
Lachine 64
London 63
New York 61
Guangzhou 50
Kunming 50
Brussels 43
Milan 43
Shenyang 40
Los Angeles 38
Centro 33
Tianjin 33
Jiaxing 32
Hebei 29
Philadelphia 28
Dong Ket 27
Hefei 27
Wuhan 27
Chicago 24
Munich 24
Hangzhou 23
Ningbo 23
Norwalk 21
Changsha 20
Jinan 20
Redwood City 20
Bremen 17
Rome 17
Falls Church 16
Venezia 16
Brno 15
Orange 13
San Francisco 13
Verona 13
Nürnberg 12
Buffalo 11
Perugia 11
Scafati 11
Tappahannock 11
Zhengzhou 11
Auburn Hills 10
Jinhua 10
Old Bridge 10
Osimo 10
Yiwu 10
Kilburn 9
Kocaeli 9
Mountain View 9
Nantong 9
New Bedfont 9
Venice 9
Changchun 8
Council Bluffs 8
Lanzhou 8
Meppel 8
Naples 8
Pescara 8
Shenzhen 8
Simi Valley 8
Taizhou 8
Tulsa 8
Washington 8
West Jordan 8
Bologna 7
Detroit 7
Scuola 7
Seoul 7
Caserta 6
Frankfurt am Main 6
Horia 6
Totale 11.298
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Nome #
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 331
Overview on Radiolabel-Free in Vitro Assays for GPCRs 316
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 281
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 278
Pharmacological characterization of the GPR17 receptor dual profile 262
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 258
The G Protein-Coupled Receptor GPR17: Overview and Update 251
Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts 237
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors. 236
1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands 232
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 214
Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations 209
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 208
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 205
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 204
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 197
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 196
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 188
GPR17 receptor modulators and their therapeutic implications: review of recent patents 188
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 177
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines 172
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 171
Synthesis and structure-activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor 170
Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin 169
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 166
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications. 164
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 163
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 162
New sensible method to quantize the intestinal absorption of receptor ligands 162
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 161
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 159
Discovery of a new series of 5-HT1A receptor agonists 157
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 156
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 156
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives 156
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 156
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 153
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 152
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice 152
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 151
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 150
null 149
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 148
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 148
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 147
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 147
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: The discovery of new functionally selective muscarinic agonists 146
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure 145
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol 145
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 145
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 141
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 141
Highly chiral muscarinic ligands: The discovery of (2S,2 ' R,3 ' S,5 ' R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M-2 partial agonist 139
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 139
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist 138
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 137
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 136
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 136
Polyamines may modulate both G protein-coupled receptors and G proteins. 133
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity. 131
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer. 130
(+)-Cyclazosin derivatives as α1-adrenoceptor antagonists 128
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 128
Structure-Activity Relatioships Among Novel Phenoxybenzamine-Related Beta-Chloroethylamines. 123
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 122
Muscarinic antagonists with multiple stereocenters: Synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl) pyrrolidine sulfoxide derivatives 122
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: Functional evaluation in rat and rabbit tissues 120
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 118
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of their iodomethylates. 115
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 110
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 109
Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward alpha1-Adrenoceptor Subtypes 108
In vitro metabolism studies of new adenosine A(2A) receptor antagonists 106
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: High affinity ligands for the alpha-adrenoceptor subtypes 106
Structure-activity relationships among novel phenoxybenzamine-related beta-chloroethylamines 105
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases 104
Synthesis and α(1)-adrenoceptor antagonist activity of tamsulosin analogues 103
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives 103
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells 102
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A(3) receptor 98
Purinergic P2X receptors: Structural models and analysis of receptor-ligand interaction 97
Structure-Activity Relationships in 2,2-Diphenyl-2-ethylthioacetic Acid Esters: Unexpected Agonist Activity in a Series of Muscarinic Antagonists. 93
Structure–activity relationships of methoctramine-relatedpolyamines as muscarinic antagonist: Effect of replacing theinner polymethylene chain with cyclic moieties 92
Existence of snoRNA, microRNA, piRNA characteristics in a novel non-coding RNA: x-ncRNA and its biological implication in Homo sapiens 91
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 91
Development of new chromatographic tools based on Adenosine A2A subtype receptor for ligand characterization and screening by FAC-MS 89
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists 89
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening 88
New purine derivatives as P2X3 receptor antagonists 86
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 86
New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A2A adenosine receptor antagonists 85
Identification of putative guanosine receptor in rat brain 83
(+)-Cyclazosin Derivatives as alpha1-Adrenoceptor Antagonists 78
Butter oil (ghee) enrichment with aromatic plants: Chemical characterization and effects on fibroblast migration in an in-vitro wound healing model 78
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A(1) adenosine receptor antagonists 74
Anticancer activity study of A3 adenosine receptor agonists 73
GPR17 ligands: synthesis and characterization of new potent agonists 72
Synthesis, Biological Evaluation, and Docking Studies ofTetrahydrofuran- Cyclopentanone- and Cyclopentanol-BasedLigands Acting at Adrenergic α1- and Serotonine 5-HT1A Receptors 71
New A2A adenosine receptor antagonists: a structure-based upside-down interaction in the receptor cavity 60
Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists 59
Totale 14.612
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Categoria #
all - tutte 64.070
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.070
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.748 0 0 0 0 189 270 241 289 219 180 138 222
2020/20212.911 146 216 205 224 200 292 530 85 247 173 364 229
2021/20221.424 136 347 40 55 64 48 84 112 105 148 130 155
2022/20231.496 171 93 60 246 149 193 10 98 240 73 120 43
2023/20241.239 161 65 73 49 46 108 63 95 139 43 49 348
2024/2025872 149 86 334 191 112 0 0 0 0 0 0 0
Totale 15.124