BUCCIONI, Michela
 Distribuzione geografica
Continente #
NA - Nord America 9.093
EU - Europa 5.424
AS - Asia 1.651
SA - Sud America 110
Continente sconosciuto - Info sul continente non disponibili 31
AF - Africa 17
OC - Oceania 6
Totale 16.332
Nazione #
US - Stati Uniti d'America 8.835
RU - Federazione Russa 1.275
PL - Polonia 1.226
CN - Cina 1.131
IT - Italia 877
DE - Germania 593
UA - Ucraina 322
GB - Regno Unito 267
SG - Singapore 261
SE - Svezia 256
CA - Canada 252
FR - Francia 224
FI - Finlandia 158
TR - Turchia 101
BR - Brasile 93
IE - Irlanda 79
BE - Belgio 46
EU - Europa 31
VN - Vietnam 31
KR - Corea 26
CZ - Repubblica Ceca 21
IN - India 19
NL - Olanda 17
RO - Romania 16
HK - Hong Kong 15
AT - Austria 12
IR - Iran 11
JP - Giappone 10
PK - Pakistan 8
AR - Argentina 6
CH - Svizzera 6
AZ - Azerbaigian 5
DK - Danimarca 5
ES - Italia 5
RS - Serbia 5
TN - Tunisia 5
AU - Australia 4
LB - Libano 4
MX - Messico 4
ZA - Sudafrica 4
AE - Emirati Arabi Uniti 3
CL - Cile 3
EC - Ecuador 3
GR - Grecia 3
IL - Israele 3
MA - Marocco 3
NO - Norvegia 3
TW - Taiwan 3
UZ - Uzbekistan 3
AL - Albania 2
BY - Bielorussia 2
DZ - Algeria 2
GE - Georgia 2
IQ - Iraq 2
JO - Giordania 2
KH - Cambogia 2
OM - Oman 2
PE - Perù 2
VE - Venezuela 2
AM - Armenia 1
AS - Samoa Americane 1
BD - Bangladesh 1
BG - Bulgaria 1
BO - Bolivia 1
CM - Camerun 1
HN - Honduras 1
HU - Ungheria 1
KE - Kenya 1
LK - Sri Lanka 1
MY - Malesia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PA - Panama 1
PH - Filippine 1
PT - Portogallo 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
Totale 16.332
Città #
Fairfield 1.156
Warsaw 994
Woodbridge 977
Jacksonville 759
Houston 624
Chandler 592
Ashburn 570
Seattle 476
Wilmington 465
Ann Arbor 443
Cambridge 417
Boardman 338
Camerino 236
Kraków 229
Nanjing 211
Toronto 184
Singapore 172
San Mateo 112
Lawrence 107
Princeton 107
Dearborn 105
Ogden 96
Istanbul 89
Beijing 85
Columbus 85
Nanchang 84
Dublin 78
Moscow 76
Düsseldorf 74
Helsinki 74
Shanghai 72
San Diego 68
Lachine 64
London 64
New York 61
Guangzhou 50
Kunming 50
Milan 50
Brussels 44
Los Angeles 42
Shenyang 40
Council Bluffs 37
Centro 33
Tianjin 33
Jiaxing 32
Hebei 29
Hefei 28
Philadelphia 28
Wuhan 28
Dong Ket 27
Chicago 26
Munich 24
Hangzhou 23
Ningbo 23
Changsha 21
Norwalk 21
Jinan 20
Redwood City 20
Bremen 17
Rome 17
Falls Church 16
Venezia 16
Brno 15
San Francisco 14
Orange 13
Verona 13
Nürnberg 12
Buffalo 11
Frankfurt am Main 11
Nuremberg 11
Perugia 11
Scafati 11
Tappahannock 11
Zhengzhou 11
Auburn Hills 10
Jinhua 10
Old Bridge 10
Osimo 10
Yiwu 10
Kilburn 9
Kocaeli 9
Mountain View 9
Nantong 9
New Bedfont 9
Shenzhen 9
São Paulo 9
Venice 9
Bologna 8
Changchun 8
Lanzhou 8
Meppel 8
Naples 8
Pescara 8
Simi Valley 8
Taizhou 8
Tulsa 8
Washington 8
West Jordan 8
Detroit 7
Santa Clara 7
Totale 11.507
Nome #
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 347
Overview on Radiolabel-Free in Vitro Assays for GPCRs 336
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 314
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 304
Pharmacological characterization of the GPR17 receptor dual profile 291
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 276
The G Protein-Coupled Receptor GPR17: Overview and Update 266
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors. 262
Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts 255
1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands 253
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 231
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 227
Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations 226
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 222
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 221
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 219
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 210
GPR17 receptor modulators and their therapeutic implications: review of recent patents 204
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 202
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 195
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines 188
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 187
Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin 184
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice 182
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 181
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 180
Synthesis and structure-activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor 179
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 178
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications. 176
New sensible method to quantize the intestinal absorption of receptor ligands 174
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 172
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 172
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 171
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 169
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 169
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 168
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 167
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 167
Discovery of a new series of 5-HT1A receptor agonists 166
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives 166
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 163
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 163
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 163
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 161
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 158
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 158
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 156
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 156
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 154
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist 154
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 153
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure 152
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 152
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: The discovery of new functionally selective muscarinic agonists 151
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol 150
null 149
(+)-Cyclazosin derivatives as α1-adrenoceptor antagonists 148
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 146
Highly chiral muscarinic ligands: The discovery of (2S,2 ' R,3 ' S,5 ' R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M-2 partial agonist 144
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: Functional evaluation in rat and rabbit tissues 143
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity. 141
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 141
Polyamines may modulate both G protein-coupled receptors and G proteins. 140
Structure-Activity Relatioships Among Novel Phenoxybenzamine-Related Beta-Chloroethylamines. 139
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer. 138
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 135
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 130
Muscarinic antagonists with multiple stereocenters: Synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl) pyrrolidine sulfoxide derivatives 128
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 127
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of their iodomethylates. 123
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 123
Structure-activity relationships among novel phenoxybenzamine-related beta-chloroethylamines 122
Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward alpha1-Adrenoceptor Subtypes 121
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells 118
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases 117
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: High affinity ligands for the alpha-adrenoceptor subtypes 115
In vitro metabolism studies of new adenosine A(2A) receptor antagonists 114
Purinergic P2X receptors: Structural models and analysis of receptor-ligand interaction 113
Synthesis and α(1)-adrenoceptor antagonist activity of tamsulosin analogues 110
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives 110
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists 109
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 108
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A(3) receptor 107
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 106
Existence of snoRNA, microRNA, piRNA characteristics in a novel non-coding RNA: x-ncRNA and its biological implication in Homo sapiens 104
Structure-Activity Relationships in 2,2-Diphenyl-2-ethylthioacetic Acid Esters: Unexpected Agonist Activity in a Series of Muscarinic Antagonists. 100
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening 98
Structure–activity relationships of methoctramine-relatedpolyamines as muscarinic antagonist: Effect of replacing theinner polymethylene chain with cyclic moieties 98
New purine derivatives as P2X3 receptor antagonists 97
Development of new chromatographic tools based on Adenosine A2A subtype receptor for ligand characterization and screening by FAC-MS 95
New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A2A adenosine receptor antagonists 93
(+)-Cyclazosin Derivatives as alpha1-Adrenoceptor Antagonists 92
Identification of putative guanosine receptor in rat brain 90
Butter oil (ghee) enrichment with aromatic plants: Chemical characterization and effects on fibroblast migration in an in-vitro wound healing model 87
GPR17 ligands: synthesis and characterization of new potent agonists 83
Anticancer activity study of A3 adenosine receptor agonists 83
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A(1) adenosine receptor antagonists 81
A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable? 81
Synthesis, Biological Evaluation, and Docking Studies ofTetrahydrofuran- Cyclopentanone- and Cyclopentanol-BasedLigands Acting at Adrenergic α1- and Serotonine 5-HT1A Receptors 79
Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists 75
Totale 16.002
Categoria #
all - tutte 69.076
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 69.076


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.048 0 0 0 0 0 0 0 289 219 180 138 222
2020/20212.911 146 216 205 224 200 292 530 85 247 173 364 229
2021/20221.424 136 347 40 55 64 48 84 112 105 148 130 155
2022/20231.496 171 93 60 246 149 193 10 98 240 73 120 43
2023/20241.239 161 65 73 49 46 108 63 95 139 43 49 348
2024/20252.491 149 86 334 191 134 220 453 924 0 0 0 0
Totale 16.743