BUCCIONI, Michela
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 11.473
EU - Europa 5.890
AS - Asia 3.659
SA - Sud America 516
AF - Africa 78
Continente sconosciuto - Info sul continente non disponibili 31
OC - Oceania 9
Totale 21.656
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 11.151
CN - Cina 1.570
RU - Federazione Russa 1.290
PL - Polonia 1.270
SG - Singapore 1.032
IT - Italia 980
DE - Germania 671
BR - Brasile 427
GB - Regno Unito 341
UA - Ucraina 325
HK - Hong Kong 318
CA - Canada 273
SE - Svezia 268
FR - Francia 251
FI - Finlandia 181
VN - Vietnam 171
KR - Corea 147
TR - Turchia 132
IE - Irlanda 80
IN - India 68
JP - Giappone 55
BE - Belgio 53
AR - Argentina 45
MX - Messico 35
ZA - Sudafrica 32
EU - Europa 31
NL - Olanda 31
BD - Bangladesh 29
ES - Italia 25
CZ - Repubblica Ceca 23
AT - Austria 21
IR - Iran 19
RO - Romania 16
EC - Ecuador 14
AE - Emirati Arabi Uniti 13
PK - Pakistan 12
TW - Taiwan 12
IQ - Iraq 11
LT - Lituania 10
RS - Serbia 10
CH - Svizzera 9
KE - Kenya 9
TN - Tunisia 9
AZ - Azerbaigian 8
PE - Perù 8
ID - Indonesia 7
IL - Israele 7
PY - Paraguay 7
AU - Australia 6
EG - Egitto 6
JO - Giordania 6
MA - Marocco 6
UZ - Uzbekistan 6
AM - Armenia 5
BG - Bulgaria 5
CL - Cile 5
DK - Danimarca 5
LB - Libano 5
SA - Arabia Saudita 5
BY - Bielorussia 4
CO - Colombia 4
DZ - Algeria 4
GE - Georgia 4
HR - Croazia 4
VE - Venezuela 4
AL - Albania 3
DO - Repubblica Dominicana 3
GR - Grecia 3
HN - Honduras 3
NO - Norvegia 3
PH - Filippine 3
CI - Costa d'Avorio 2
ET - Etiopia 2
KH - Cambogia 2
KW - Kuwait 2
MY - Malesia 2
NP - Nepal 2
OM - Oman 2
PA - Panama 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
AS - Samoa Americane 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
CM - Camerun 1
CR - Costa Rica 1
DM - Dominica 1
EE - Estonia 1
GD - Grenada 1
GM - Gambi 1
HU - Ungheria 1
IS - Islanda 1
JM - Giamaica 1
KI - Kiribati 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LV - Lettonia 1
LY - Libia 1
MU - Mauritius 1
MW - Malawi 1
Totale 21.648
Salva come PNG Salva come JPEG
Città #
Fairfield 1.156
Warsaw 1.029
Woodbridge 977
Ashburn 873
Dallas 804
Jacksonville 759
Houston 636
Chandler 592
Seattle 483
Wilmington 468
Singapore 454
Ann Arbor 443
Cambridge 417
Boardman 338
Hong Kong 303
Camerino 253
Beijing 237
Kraków 229
Nanjing 211
Toronto 189
Los Angeles 187
The Dalles 152
New York 133
Seoul 124
Tongling 113
Columbus 112
San Mateo 112
Lawrence 107
Princeton 107
Dearborn 105
Istanbul 104
Ogden 96
Nanchang 84
Moscow 82
Dublin 79
Düsseldorf 79
London 79
Buffalo 77
Helsinki 76
Shanghai 74
San Diego 68
Munich 65
Lachine 64
Chicago 58
Milan 58
Guangzhou 55
Council Bluffs 53
Brussels 51
São Paulo 51
Kunming 50
Ho Chi Minh City 49
Santa Clara 45
Shenyang 42
Tokyo 41
Tianjin 36
Centro 33
Jiaxing 33
Hanoi 32
Rome 30
Hebei 29
Orem 29
Frankfurt am Main 28
Hefei 28
Philadelphia 28
Wuhan 28
Denver 27
Dong Ket 27
Hangzhou 26
Brooklyn 25
Ningbo 23
Boston 22
Changsha 21
Norwalk 21
Poplar 21
San Francisco 21
San Jose 21
Jinan 20
Nuremberg 20
Phoenix 20
Redwood City 20
Chennai 19
Johannesburg 19
Atlanta 18
Turku 18
Bremen 17
Falls Church 16
Venezia 16
Brno 15
Redondo Beach 15
Rio de Janeiro 15
Tampa 15
Verona 15
Mexico City 13
Orange 13
Manchester 12
Nürnberg 12
Stockholm 12
Zhengzhou 12
Belo Horizonte 11
Montreal 11
Totale 14.646
Salva come PNG Salva come JPEG
Nome #
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors. 582
1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands 561
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 493
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 405
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 384
Overview on Radiolabel-Free in Vitro Assays for GPCRs 379
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 355
Pharmacological characterization of the GPR17 receptor dual profile 355
The G Protein-Coupled Receptor GPR17: Overview and Update 327
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 326
Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts 313
GPR17 receptor modulators and their therapeutic implications: review of recent patents 281
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 271
Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations 270
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 262
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 260
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice 258
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 252
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 252
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 249
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 248
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 240
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 237
Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin 231
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 227
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines 222
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 214
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 214
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 212
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 212
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications. 212
Synthesis and structure-activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor 212
New sensible method to quantize the intestinal absorption of receptor ligands 210
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 208
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 206
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 202
(+)-Cyclazosin derivatives as α1-adrenoceptor antagonists 201
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 201
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 200
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 198
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: Functional evaluation in rat and rabbit tissues 198
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 197
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives 196
Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward alpha1-Adrenoceptor Subtypes 196
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 195
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 195
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 193
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 193
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 192
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 191
Discovery of a new series of 5-HT1A receptor agonists 191
Structure-Activity Relatioships Among Novel Phenoxybenzamine-Related Beta-Chloroethylamines. 190
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist 190
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 189
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 187
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol 185
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 184
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure 177
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 177
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: The discovery of new functionally selective muscarinic agonists 176
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity. 176
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer. 171
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 168
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 166
Highly chiral muscarinic ligands: The discovery of (2S,2 ' R,3 ' S,5 ' R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M-2 partial agonist 164
Polyamines may modulate both G protein-coupled receptors and G proteins. 164
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 164
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 161
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 161
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 160
Structure-activity relationships among novel phenoxybenzamine-related beta-chloroethylamines 154
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists 154
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of their iodomethylates. 153
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives 152
Muscarinic antagonists with multiple stereocenters: Synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl) pyrrolidine sulfoxide derivatives 152
null 149
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells 149
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 145
In vitro metabolism studies of new adenosine A(2A) receptor antagonists 143
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: High affinity ligands for the alpha-adrenoceptor subtypes 143
Purinergic P2X receptors: Structural models and analysis of receptor-ligand interaction 143
(+)-Cyclazosin Derivatives as alpha1-Adrenoceptor Antagonists 143
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases 142
A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable? 140
Synthesis and α(1)-adrenoceptor antagonist activity of tamsulosin analogues 138
Structure-Activity Relationships in 2,2-Diphenyl-2-ethylthioacetic Acid Esters: Unexpected Agonist Activity in a Series of Muscarinic Antagonists. 131
Existence of snoRNA, microRNA, piRNA characteristics in a novel non-coding RNA: x-ncRNA and its biological implication in Homo sapiens 129
New purine derivatives as P2X3 receptor antagonists 129
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A(3) receptor 128
Structure–activity relationships of methoctramine-relatedpolyamines as muscarinic antagonist: Effect of replacing theinner polymethylene chain with cyclic moieties 127
Development of new chromatographic tools based on Adenosine A2A subtype receptor for ligand characterization and screening by FAC-MS 126
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening 126
Butter oil (ghee) enrichment with aromatic plants: Chemical characterization and effects on fibroblast migration in an in-vitro wound healing model 123
Anticancer activity study of A3 adenosine receptor agonists 122
A2A adenosine receptor ligands: effects on alcohol intake in alcohol-preferring rats 121
“Dual Anta-Inhibitors” of the A2A Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies 118
New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A2A adenosine receptor antagonists 118
Adenosine A2A Receptor Antagonists: Chemistry, SARs, and Therapeutic Potential 114
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A(1) adenosine receptor antagonists 112
GPR17 ligands: synthesis and characterization of new potent agonists 111
Totale 20.624
Salva come PNG Salva come JPEG
Categoria #
all - tutte 88.378
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 88.378
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.920 0 0 0 0 0 292 530 85 247 173 364 229
2021/20221.424 136 347 40 55 64 48 84 112 105 148 130 155
2022/20231.496 171 93 60 246 149 193 10 98 240 73 120 43
2023/20241.239 161 65 73 49 46 108 63 95 139 43 49 348
2024/20254.005 149 86 334 191 134 220 453 1.037 303 270 291 537
2025/20263.819 382 413 1.136 829 722 337 0 0 0 0 0 0
Totale 22.076