BUCCIONI, Michela
 Distribuzione geografica
Continente #
NA - Nord America 14.527
EU - Europa 6.561
AS - Asia 4.637
SA - Sud America 593
Continente sconosciuto - Info sul continente non disponibili 477
AF - Africa 191
OC - Oceania 14
Totale 27.000
Nazione #
US - Stati Uniti d'America 14.099
CN - Cina 1.799
SG - Singapore 1.379
RU - Federazione Russa 1.292
PL - Polonia 1.283
IT - Italia 1.216
DE - Germania 716
BR - Brasile 474
GB - Regno Unito 445
HK - Hong Kong 403
FR - Francia 382
VN - Vietnam 358
UA - Ucraina 329
CA - Canada 317
SE - Svezia 273
FI - Finlandia 248
KR - Corea 150
TR - Turchia 136
ZA - Sudafrica 125
IN - India 92
IE - Irlanda 88
JP - Giappone 79
BE - Belgio 55
NL - Olanda 55
MX - Messico 54
AR - Argentina 50
BD - Bangladesh 42
ES - Italia 33
EU - Europa 31
PK - Pakistan 28
CZ - Repubblica Ceca 23
IR - Iran 23
AT - Austria 21
EC - Ecuador 20
IQ - Iraq 18
TW - Taiwan 18
RO - Romania 17
AE - Emirati Arabi Uniti 14
CO - Colombia 13
CR - Costa Rica 13
HN - Honduras 13
EG - Egitto 12
KE - Kenya 12
LT - Lituania 12
TN - Tunisia 12
AU - Australia 11
CH - Svizzera 11
ID - Indonesia 11
RS - Serbia 11
AZ - Azerbaigian 9
IL - Israele 9
JM - Giamaica 9
PE - Perù 9
PY - Paraguay 9
EE - Estonia 8
SA - Arabia Saudita 8
VE - Venezuela 8
CL - Cile 7
JO - Giordania 7
UZ - Uzbekistan 7
AM - Armenia 6
MA - Marocco 6
PH - Filippine 6
BG - Bulgaria 5
BY - Bielorussia 5
DK - Danimarca 5
DZ - Algeria 5
LB - Libano 5
MY - Malesia 5
OM - Oman 5
TH - Thailandia 5
TT - Trinidad e Tobago 5
AL - Albania 4
CI - Costa d'Avorio 4
DO - Repubblica Dominicana 4
GE - Georgia 4
HR - Croazia 4
NP - Nepal 4
SC - Seychelles 4
ET - Etiopia 3
GR - Grecia 3
GT - Guatemala 3
KW - Kuwait 3
NO - Norvegia 3
SI - Slovenia 3
BO - Bolivia 2
CW - ???statistics.table.value.countryCode.CW??? 2
HU - Ungheria 2
KH - Cambogia 2
MU - Mauritius 2
PA - Panama 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
AS - Samoa Americane 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BS - Bahamas 1
CM - Camerun 1
DM - Dominica 1
GD - Grenada 1
Totale 26.538
Città #
Ashburn 1.247
Fairfield 1.157
Warsaw 1.041
Woodbridge 977
Dallas 845
San Jose 775
Jacksonville 762
Singapore 703
Houston 645
Chandler 592
Council Bluffs 512
Seattle 486
Wilmington 472
Ann Arbor 443
Cambridge 417
Hong Kong 374
Boardman 338
Beijing 303
Camerino 263
Kraków 229
Los Angeles 221
Nanjing 213
New York 202
Toronto 202
The Dalles 171
Helsinki 141
Seoul 124
Columbus 117
Ho Chi Minh City 114
Tongling 113
San Mateo 112
Santa Clara 112
Princeton 110
Johannesburg 109
Lawrence 107
Dearborn 105
Istanbul 105
Ogden 98
Lauterbourg 96
Chicago 88
Dublin 87
Nanchang 84
Buffalo 83
London 82
Moscow 82
Düsseldorf 79
Shanghai 79
Phoenix 76
Guangzhou 70
Hanoi 70
Milan 69
San Diego 69
Munich 65
Lachine 64
Tokyo 61
São Paulo 60
Frankfurt am Main 57
Brussels 51
Kunming 50
Rome 48
St Louis 45
Edinburgh 44
Shenyang 43
Orem 42
Tianjin 39
Centro 34
Denver 33
Jiaxing 33
Philadelphia 32
Brooklyn 29
Hebei 29
Hefei 28
Washington 28
Wuhan 28
Atlanta 27
Dong Ket 27
Boston 26
Hangzhou 26
Mexico City 26
San Francisco 26
Trieste 25
Chennai 24
Ningbo 23
Changsha 22
Manchester 22
Norwalk 21
Poplar 21
Jinan 20
Nuremberg 20
Redwood City 20
Turku 18
Amsterdam 17
Bremen 17
Haiphong 17
Rio de Janeiro 17
Falls Church 16
Montreal 16
Venezia 16
Brno 15
Da Nang 15
Totale 17.654
Nome #
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors. 625
1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands 619
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 539
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 468
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 424
Overview on Radiolabel-Free in Vitro Assays for GPCRs 415
Pharmacological characterization of the GPR17 receptor dual profile 413
GPR17 receptor modulators and their therapeutic implications: review of recent patents 410
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 396
The G Protein-Coupled Receptor GPR17: Overview and Update 394
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 391
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 369
Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts 365
Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations 309
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 305
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice 301
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 298
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 297
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 296
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 288
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 279
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 277
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 276
Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin 265
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 265
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications. 257
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 256
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines 254
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 249
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 247
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 247
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 245
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 242
(+)-Cyclazosin derivatives as α1-adrenoceptor antagonists 242
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 240
Structure-Activity Relatioships Among Novel Phenoxybenzamine-Related Beta-Chloroethylamines. 240
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: Functional evaluation in rat and rabbit tissues 240
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist 240
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 239
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 235
New sensible method to quantize the intestinal absorption of receptor ligands 235
Synthesis and structure-activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor 233
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 232
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives 231
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 231
Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward alpha1-Adrenoceptor Subtypes 229
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 229
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 226
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 223
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 221
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 220
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol 220
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 218
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity. 215
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 214
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 213
Discovery of a new series of 5-HT1A receptor agonists 212
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 210
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 209
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: The discovery of new functionally selective muscarinic agonists 208
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 207
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 205
Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease 205
Highly chiral muscarinic ligands: The discovery of (2S,2 ' R,3 ' S,5 ' R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M-2 partial agonist 204
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 201
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure 200
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer. 198
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 197
A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable? 196
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 195
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 192
Polyamines may modulate both G protein-coupled receptors and G proteins. 190
Structure-activity relationships among novel phenoxybenzamine-related beta-chloroethylamines 190
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 188
Adenine derivatives as inhibitors of the casein kinase CK1delta enzyme 187
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists 187
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: High affinity ligands for the alpha-adrenoceptor subtypes 183
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of their iodomethylates. 179
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells 178
In vitro metabolism studies of new adenosine A(2A) receptor antagonists 177
(+)-Cyclazosin Derivatives as alpha1-Adrenoceptor Antagonists 177
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives 176
Purinergic P2X receptors: Structural models and analysis of receptor-ligand interaction 176
Muscarinic antagonists with multiple stereocenters: Synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl) pyrrolidine sulfoxide derivatives 175
Synthesis and α(1)-adrenoceptor antagonist activity of tamsulosin analogues 169
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening 166
A2A adenosine receptor ligands: effects on alcohol intake in alcohol-preferring rats 163
Structure-Activity Relationships in 2,2-Diphenyl-2-ethylthioacetic Acid Esters: Unexpected Agonist Activity in a Series of Muscarinic Antagonists. 163
Structure–activity relationships of methoctramine-relatedpolyamines as muscarinic antagonist: Effect of replacing theinner polymethylene chain with cyclic moieties 161
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases 158
Identification of putative guanosine receptor in rat brain 157
Adenosine A2A Receptor Antagonists: Chemistry, SARs, and Therapeutic Potential 156
New purine derivatives as P2X3 receptor antagonists 156
“Dual Anta-Inhibitors” of the A2A Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies 154
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A(3) receptor 154
Anticancer activity study of A3 adenosine receptor agonists 153
Existence of snoRNA, microRNA, piRNA characteristics in a novel non-coding RNA: x-ncRNA and its biological implication in Homo sapiens 151
null 149
Combined therapy of A1AR agonists and A2AAR antagonists in neuroinflammation 149
Development of new chromatographic tools based on Adenosine A2A subtype receptor for ligand characterization and screening by FAC-MS 147
Totale 24.455
Categoria #
all - tutte 106.011
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 106.011


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022901 0 0 0 55 64 48 84 112 105 148 130 155
2022/20231.496 171 93 60 246 149 193 10 98 240 73 120 43
2023/20241.239 161 65 73 49 46 108 63 95 139 43 49 348
2024/20254.005 149 86 334 191 134 220 453 1.037 303 270 291 537
2025/20266.788 382 413 1.136 829 722 471 995 444 410 419 369 198
2026/20271.955 477 268 498 712 0 0 0 0 0 0 0 0
Totale 27.000