BUCCIONI, Michela
 Distribuzione geografica
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Continente #
NA - Nord America 13.407
EU - Europa 6.439
AS - Asia 4.613
SA - Sud America 570
Continente sconosciuto - Info sul continente non disponibili 475
AF - Africa 185
OC - Oceania 14
Totale 25.703
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Nazione #
US - Stati Uniti d'America 13.021
CN - Cina 1.794
SG - Singapore 1.376
RU - Federazione Russa 1.292
PL - Polonia 1.283
IT - Italia 1.152
DE - Germania 713
BR - Brasile 455
GB - Regno Unito 410
HK - Hong Kong 396
FR - Francia 382
VN - Vietnam 357
UA - Ucraina 328
CA - Canada 299
SE - Svezia 270
FI - Finlandia 248
KR - Corea 150
TR - Turchia 136
ZA - Sudafrica 124
IN - India 91
IE - Irlanda 87
JP - Giappone 78
BE - Belgio 55
MX - Messico 53
AR - Argentina 50
NL - Olanda 50
BD - Bangladesh 38
ES - Italia 31
EU - Europa 31
PK - Pakistan 27
CZ - Repubblica Ceca 23
IR - Iran 23
AT - Austria 21
EC - Ecuador 19
IQ - Iraq 18
TW - Taiwan 18
RO - Romania 17
AE - Emirati Arabi Uniti 14
LT - Lituania 12
TN - Tunisia 12
AU - Australia 11
CH - Svizzera 11
KE - Kenya 11
RS - Serbia 11
CO - Colombia 10
EG - Egitto 10
ID - Indonesia 10
AZ - Azerbaigian 9
IL - Israele 9
PE - Perù 9
PY - Paraguay 9
SA - Arabia Saudita 8
VE - Venezuela 8
CL - Cile 7
HN - Honduras 7
JM - Giamaica 7
JO - Giordania 7
UZ - Uzbekistan 7
AM - Armenia 6
MA - Marocco 6
PH - Filippine 6
BG - Bulgaria 5
BY - Bielorussia 5
DK - Danimarca 5
DZ - Algeria 5
LB - Libano 5
MY - Malesia 5
OM - Oman 5
TH - Thailandia 5
AL - Albania 4
CI - Costa d'Avorio 4
CR - Costa Rica 4
GE - Georgia 4
HR - Croazia 4
NP - Nepal 4
DO - Repubblica Dominicana 3
ET - Etiopia 3
GR - Grecia 3
KW - Kuwait 3
NO - Norvegia 3
SI - Slovenia 3
TT - Trinidad e Tobago 3
BO - Bolivia 2
GT - Guatemala 2
HU - Ungheria 2
KH - Cambogia 2
MU - Mauritius 2
PA - Panama 2
SC - Seychelles 2
SK - Slovacchia (Repubblica Slovacca) 2
AS - Samoa Americane 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CM - Camerun 1
DM - Dominica 1
EE - Estonia 1
GD - Grenada 1
GM - Gambi 1
IS - Islanda 1
KI - Kiribati 1
Totale 25.244
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Città #
Fairfield 1.157
Ashburn 1.059
Warsaw 1.041
Woodbridge 977
Dallas 828
Jacksonville 761
Singapore 701
Houston 642
San Jose 619
Chandler 592
Council Bluffs 504
Seattle 484
Wilmington 470
Ann Arbor 443
Cambridge 417
Hong Kong 371
Boardman 338
Beijing 301
Camerino 263
Kraków 229
Nanjing 213
Los Angeles 205
Toronto 196
The Dalles 170
New York 152
Helsinki 141
Seoul 124
Ho Chi Minh City 114
Columbus 113
Tongling 113
San Mateo 112
Johannesburg 109
Lawrence 107
Princeton 107
Dearborn 105
Istanbul 105
Santa Clara 99
Ogden 97
Lauterbourg 96
Dublin 86
Nanchang 84
Buffalo 82
Moscow 82
London 81
Düsseldorf 79
Shanghai 79
Guangzhou 70
Hanoi 70
Chicago 68
Milan 68
San Diego 68
Munich 65
Lachine 64
Tokyo 61
Frankfurt am Main 57
São Paulo 54
Brussels 51
Kunming 50
Edinburgh 44
Rome 44
Shenyang 43
St Louis 43
Orem 41
Tianjin 39
Centro 34
Phoenix 34
Jiaxing 33
Denver 30
Philadelphia 30
Hebei 29
Hefei 28
Wuhan 28
Dong Ket 27
Hangzhou 26
Brooklyn 25
Mexico City 25
Trieste 25
Boston 24
Chennai 24
San Francisco 24
Ningbo 23
Changsha 22
Manchester 22
Atlanta 21
Norwalk 21
Poplar 21
Jinan 20
Nuremberg 20
Redwood City 20
Turku 18
Amsterdam 17
Bremen 17
Haiphong 17
Rio de Janeiro 17
Falls Church 16
Montreal 16
Venezia 16
Brno 15
Da Nang 15
Redondo Beach 15
Totale 17.063
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Nome #
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors. 615
1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands 602
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 534
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 460
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 412
Overview on Radiolabel-Free in Vitro Assays for GPCRs 407
Pharmacological characterization of the GPR17 receptor dual profile 402
GPR17 receptor modulators and their therapeutic implications: review of recent patents 393
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 390
The G Protein-Coupled Receptor GPR17: Overview and Update 375
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 360
Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts 354
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 337
Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations 302
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 297
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice 293
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 288
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 281
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 278
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 273
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 271
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 270
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 265
Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin 252
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines 250
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 250
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 247
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications. 246
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 241
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 240
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 240
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 238
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 235
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 235
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist 232
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: Functional evaluation in rat and rabbit tissues 230
New sensible method to quantize the intestinal absorption of receptor ligands 228
(+)-Cyclazosin derivatives as α1-adrenoceptor antagonists 227
Structure-Activity Relatioships Among Novel Phenoxybenzamine-Related Beta-Chloroethylamines. 226
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 224
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 224
Synthesis and structure-activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor 224
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 224
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 222
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 221
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 219
Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward alpha1-Adrenoceptor Subtypes 218
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives 217
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 215
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 214
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 213
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 212
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol 211
Discovery of a new series of 5-HT1A receptor agonists 206
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 205
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 205
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 204
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 201
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 201
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity. 197
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 197
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: The discovery of new functionally selective muscarinic agonists 196
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 195
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure 191
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer. 190
Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease 189
A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable? 189
Highly chiral muscarinic ligands: The discovery of (2S,2 ' R,3 ' S,5 ' R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M-2 partial agonist 188
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 186
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 185
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists 182
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 181
Polyamines may modulate both G protein-coupled receptors and G proteins. 180
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 178
Adenine derivatives as inhibitors of the casein kinase CK1delta enzyme 177
Structure-activity relationships among novel phenoxybenzamine-related beta-chloroethylamines 175
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells 172
Purinergic P2X receptors: Structural models and analysis of receptor-ligand interaction 169
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of their iodomethylates. 168
In vitro metabolism studies of new adenosine A(2A) receptor antagonists 167
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives 166
Muscarinic antagonists with multiple stereocenters: Synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl) pyrrolidine sulfoxide derivatives 166
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: High affinity ligands for the alpha-adrenoceptor subtypes 165
(+)-Cyclazosin Derivatives as alpha1-Adrenoceptor Antagonists 165
Synthesis and α(1)-adrenoceptor antagonist activity of tamsulosin analogues 162
A2A adenosine receptor ligands: effects on alcohol intake in alcohol-preferring rats 155
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening 154
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases 152
New purine derivatives as P2X3 receptor antagonists 151
Structure-Activity Relationships in 2,2-Diphenyl-2-ethylthioacetic Acid Esters: Unexpected Agonist Activity in a Series of Muscarinic Antagonists. 151
Adenosine A2A Receptor Antagonists: Chemistry, SARs, and Therapeutic Potential 149
null 149
Structure–activity relationships of methoctramine-relatedpolyamines as muscarinic antagonist: Effect of replacing theinner polymethylene chain with cyclic moieties 148
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A(3) receptor 146
“Dual Anta-Inhibitors” of the A2A Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies 145
Existence of snoRNA, microRNA, piRNA characteristics in a novel non-coding RNA: x-ncRNA and its biological implication in Homo sapiens 142
Development of new chromatographic tools based on Adenosine A2A subtype receptor for ligand characterization and screening by FAC-MS 141
Anticancer activity study of A3 adenosine receptor agonists 141
Butter oil (ghee) enrichment with aromatic plants: Chemical characterization and effects on fibroblast migration in an in-vitro wound healing model 140
New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A2A adenosine receptor antagonists 137
Totale 23.433
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Categoria #
all - tutte 101.336
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 101.336
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.288 0 347 40 55 64 48 84 112 105 148 130 155
2022/20231.496 171 93 60 246 149 193 10 98 240 73 120 43
2023/20241.239 161 65 73 49 46 108 63 95 139 43 49 348
2024/20254.005 149 86 334 191 134 220 453 1.037 303 270 291 537
2025/20266.788 382 413 1.136 829 722 471 995 444 410 419 369 198
2026/2027658 477 181 0 0 0 0 0 0 0 0 0 0
Totale 25.703