BUCCIONI, Michela
 Distribuzione geografica
Continente #
NA - Nord America 8.621
EU - Europa 3.881
AS - Asia 875
Continente sconosciuto - Info sul continente non disponibili 31
SA - Sud America 16
AF - Africa 6
OC - Oceania 5
Totale 13.435
Nazione #
US - Stati Uniti d'America 8.368
PL - Polonia 1.225
CN - Cina 752
IT - Italia 747
DE - Germania 545
UA - Ucraina 321
SE - Svezia 256
CA - Canada 249
GB - Regno Unito 248
FR - Francia 219
FI - Finlandia 138
IE - Irlanda 77
BE - Belgio 38
EU - Europa 31
VN - Vietnam 29
KR - Corea 25
RO - Romania 15
RU - Federazione Russa 15
NL - Olanda 14
IN - India 12
TR - Turchia 12
IR - Iran 9
BR - Brasile 7
SG - Singapore 7
HK - Hong Kong 6
DK - Danimarca 5
JP - Giappone 5
AR - Argentina 4
AT - Austria 4
AU - Australia 4
LB - Libano 4
RS - Serbia 4
CL - Cile 3
NO - Norvegia 3
PK - Pakistan 3
CH - Svizzera 2
CZ - Repubblica Ceca 2
DZ - Algeria 2
GR - Grecia 2
MX - Messico 2
TN - Tunisia 2
AE - Emirati Arabi Uniti 1
AS - Samoa Americane 1
BD - Bangladesh 1
CM - Camerun 1
EC - Ecuador 1
ES - Italia 1
GE - Georgia 1
HN - Honduras 1
IL - Israele 1
IQ - Iraq 1
JO - Giordania 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
SA - Arabia Saudita 1
TH - Thailandia 1
TW - Taiwan 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 13.435
Città #
Fairfield 1.156
Warsaw 994
Woodbridge 977
Jacksonville 759
Houston 624
Chandler 592
Ashburn 547
Seattle 475
Wilmington 465
Ann Arbor 443
Cambridge 417
Kraków 229
Nanjing 206
Toronto 183
Camerino 173
San Mateo 112
Lawrence 107
Princeton 107
Dearborn 105
Ogden 96
Boardman 91
Columbus 85
Nanchang 84
Dublin 76
Düsseldorf 74
San Diego 68
Lachine 64
Beijing 63
Helsinki 60
New York 60
Kunming 50
London 49
Milan 42
Shenyang 40
Brussels 36
Centro 33
Tianjin 33
Hebei 29
Philadelphia 28
Dong Ket 27
Hefei 27
Ningbo 23
Jiaxing 22
Norwalk 21
Changsha 20
Redwood City 20
Hangzhou 19
Jinan 19
Shanghai 19
Bremen 17
Falls Church 16
Guangzhou 16
Venezia 16
Orange 13
San Francisco 13
Verona 13
Nürnberg 12
Scafati 11
Tappahannock 11
Zhengzhou 11
Auburn Hills 10
Chicago 10
Old Bridge 10
Kilburn 9
Kocaeli 9
Los Angeles 9
Mountain View 9
New Bedfont 9
Perugia 9
Venice 9
Buffalo 8
Changchun 8
Council Bluffs 8
Lanzhou 8
Meppel 8
Naples 8
Simi Valley 8
Taizhou 8
Tulsa 8
Washington 8
West Jordan 8
Bologna 7
Detroit 7
Scuola 7
Seoul 7
Caserta 6
Horia 6
Indiana 6
Münster 6
Rome 6
Sindelfingen 6
Suceava 6
Ancona 5
Ardabil 5
Buti 5
Pawcatuck 5
Portland 5
Prescot 5
Southwark 5
Varese 5
Totale 10.489
Nome #
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 320
Overview on Radiolabel-Free in Vitro Assays for GPCRs 308
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 258
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 241
The G Protein-Coupled Receptor GPR17: Overview and Update 240
Pharmacological characterization of the GPR17 receptor dual profile 234
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 232
Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts 223
1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands 211
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors. 209
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 203
Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations 202
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 197
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 196
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 186
GPR17 receptor modulators and their therapeutic implications: review of recent patents 181
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 179
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 175
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 173
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 169
Synthesis and structure-activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor 163
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 163
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines 162
Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin 159
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications. 157
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 156
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 156
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 150
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 150
null 149
Discovery of a new series of 5-HT1A receptor agonists 149
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 149
New sensible method to quantize the intestinal absorption of receptor ligands 149
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 147
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 147
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives 147
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 144
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 144
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 143
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 142
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 141
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 141
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 141
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 140
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 139
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice 138
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 137
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol 137
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure 136
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: The discovery of new functionally selective muscarinic agonists 135
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 134
Highly chiral muscarinic ligands: The discovery of (2S,2 ' R,3 ' S,5 ' R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M-2 partial agonist 132
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 130
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 130
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist 128
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 126
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 125
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity. 124
Polyamines may modulate both G protein-coupled receptors and G proteins. 124
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 122
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer. 122
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 121
(+)-Cyclazosin derivatives as α1-adrenoceptor antagonists 115
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 115
Muscarinic antagonists with multiple stereocenters: Synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl) pyrrolidine sulfoxide derivatives 115
Structure-Activity Relatioships Among Novel Phenoxybenzamine-Related Beta-Chloroethylamines. 114
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of their iodomethylates. 108
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 105
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: Functional evaluation in rat and rabbit tissues 101
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 100
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 99
In vitro metabolism studies of new adenosine A(2A) receptor antagonists 97
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives 97
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases 95
Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward alpha1-Adrenoceptor Subtypes 94
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells 93
Synthesis and α(1)-adrenoceptor antagonist activity of tamsulosin analogues 92
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A(3) receptor 92
Structure-activity relationships among novel phenoxybenzamine-related beta-chloroethylamines 92
Purinergic P2X receptors: Structural models and analysis of receptor-ligand interaction 90
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: High affinity ligands for the alpha-adrenoceptor subtypes 88
Structure-Activity Relationships in 2,2-Diphenyl-2-ethylthioacetic Acid Esters: Unexpected Agonist Activity in a Series of Muscarinic Antagonists. 86
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 83
Structure–activity relationships of methoctramine-relatedpolyamines as muscarinic antagonist: Effect of replacing theinner polymethylene chain with cyclic moieties 82
Development of new chromatographic tools based on Adenosine A2A subtype receptor for ligand characterization and screening by FAC-MS 79
New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A2A adenosine receptor antagonists 78
Existence of snoRNA, microRNA, piRNA characteristics in a novel non-coding RNA: x-ncRNA and its biological implication in Homo sapiens 77
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists 77
New purine derivatives as P2X3 receptor antagonists 76
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening 76
Identification of putative guanosine receptor in rat brain 75
(+)-Cyclazosin Derivatives as alpha1-Adrenoceptor Antagonists 69
Butter oil (ghee) enrichment with aromatic plants: Chemical characterization and effects on fibroblast migration in an in-vitro wound healing model 68
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 67
Anticancer activity study of A3 adenosine receptor agonists 66
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A(1) adenosine receptor antagonists 65
GPR17 ligands: synthesis and characterization of new potent agonists 63
Synthesis, Biological Evaluation, and Docking Studies ofTetrahydrofuran- Cyclopentanone- and Cyclopentanol-BasedLigands Acting at Adrenergic α1- and Serotonine 5-HT1A Receptors 62
null 56
Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists 50
Totale 13.523
Categoria #
all - tutte 51.191
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.191


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019786 0 0 0 0 0 0 0 0 0 154 300 332
2019/20203.177 350 148 291 640 189 270 241 289 219 180 138 222
2020/20212.911 146 216 205 224 200 292 530 85 247 173 364 229
2021/20221.424 136 347 40 55 64 48 84 112 105 148 130 155
2022/20231.496 171 93 60 246 149 193 10 98 240 73 120 43
2023/2024815 161 65 73 49 46 108 63 95 139 16 0 0
Totale 13.828