BUCCIONI, Michela
 Distribuzione geografica
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Continente #
NA - Nord America 8.690
EU - Europa 3.961
AS - Asia 1.289
Continente sconosciuto - Info sul continente non disponibili 31
SA - Sud America 19
AF - Africa 6
OC - Oceania 5
Totale 14.001
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Nazione #
US - Stati Uniti d'America 8.435
PL - Polonia 1.225
CN - Cina 1.082
IT - Italia 770
DE - Germania 559
UA - Ucraina 321
GB - Regno Unito 262
SE - Svezia 256
CA - Canada 250
FR - Francia 219
FI - Finlandia 138
SG - Singapore 79
IE - Irlanda 78
BE - Belgio 45
EU - Europa 31
VN - Vietnam 29
KR - Corea 26
CZ - Repubblica Ceca 20
RU - Federazione Russa 18
IN - India 15
RO - Romania 15
HK - Hong Kong 14
NL - Olanda 14
TR - Turchia 12
BR - Brasile 10
IR - Iran 9
DK - Danimarca 5
JP - Giappone 5
AR - Argentina 4
AT - Austria 4
AU - Australia 4
LB - Libano 4
RS - Serbia 4
CL - Cile 3
MX - Messico 3
NO - Norvegia 3
PK - Pakistan 3
CH - Svizzera 2
DZ - Algeria 2
GR - Grecia 2
TN - Tunisia 2
AE - Emirati Arabi Uniti 1
AS - Samoa Americane 1
BD - Bangladesh 1
CM - Camerun 1
EC - Ecuador 1
ES - Italia 1
GE - Georgia 1
HN - Honduras 1
IL - Israele 1
IQ - Iraq 1
JO - Giordania 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
SA - Arabia Saudita 1
TH - Thailandia 1
TW - Taiwan 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 14.001
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Città #
Fairfield 1.156
Warsaw 994
Woodbridge 977
Jacksonville 759
Houston 624
Chandler 592
Ashburn 549
Seattle 475
Wilmington 465
Ann Arbor 443
Cambridge 417
Kraków 229
Nanjing 210
Toronto 183
Camerino 181
Boardman 112
San Mateo 112
Lawrence 107
Princeton 107
Dearborn 105
Ogden 96
Columbus 85
Nanchang 84
Beijing 81
Dublin 77
Düsseldorf 74
San Diego 68
Lachine 64
London 63
Shanghai 63
Helsinki 60
New York 60
Guangzhou 50
Kunming 50
Singapore 46
Brussels 43
Milan 43
Shenyang 40
Centro 33
Tianjin 33
Jiaxing 32
Hebei 29
Philadelphia 28
Dong Ket 27
Hefei 27
Wuhan 27
Chicago 24
Ningbo 23
Hangzhou 22
Norwalk 21
Changsha 20
Redwood City 20
Jinan 19
Los Angeles 18
Bremen 17
Falls Church 16
Venezia 16
Brno 15
Orange 13
San Francisco 13
Verona 13
Nürnberg 12
Scafati 11
Tappahannock 11
Zhengzhou 11
Auburn Hills 10
Buffalo 10
Jinhua 10
Munich 10
Old Bridge 10
Yiwu 10
Kilburn 9
Kocaeli 9
Mountain View 9
New Bedfont 9
Perugia 9
Venice 9
Changchun 8
Council Bluffs 8
Lanzhou 8
Meppel 8
Naples 8
Rome 8
Simi Valley 8
Taizhou 8
Tulsa 8
Washington 8
West Jordan 8
Bologna 7
Detroit 7
Scuola 7
Seoul 7
Shenzhen 7
Caserta 6
Horia 6
Indiana 6
Münster 6
Sindelfingen 6
Suceava 6
Ancona 5
Totale 10.773
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Nome #
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor 324
Overview on Radiolabel-Free in Vitro Assays for GPCRs 310
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype 271
A2AR agonists/A3R antagonists: design, synthesis, and biological evaluation of new ligands with dual activity 259
2’,3’-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents 248
Pharmacological characterization of the GPR17 receptor dual profile 248
The G Protein-Coupled Receptor GPR17: Overview and Update 245
Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts 230
1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands 222
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors. 219
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia 206
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 204
Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations 202
Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists 197
Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor 191
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 188
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 185
GPR17 receptor modulators and their therapeutic implications: review of recent patents 184
Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists 177
Neuropeptide S Receptor: recent updates on non-peptide antagonist discovery 173
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain 167
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines 166
Synthesis and structure-activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor 166
Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin 164
Levels of polychlorinated biphenyls in fish and shellfish from the Adriatic Sea 161
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications. 160
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity 160
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA 156
New sensible method to quantize the intestinal absorption of receptor ligands 155
Discovery of a new series of 5-HT1A receptor agonists 153
“Third Joint Italian-German Purine Club Meeting - Purinergic Receptors: New Frontiers for Novel Therapies” 153
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives 153
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells 153
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 152
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 151
null 149
Evidence for the existence of a specific G protein-coupled receptor activated by guanosine 148
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists 147
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview 147
Molecular modeling studies on the human neuropeptide S receptor and its antagonists. 145
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17 144
Molecular modeling study on potent and selective adenosine A3 receptor agonists. 144
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice 144
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors 143
Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor 143
Purinergic P2X receptors: Structural models and analysis of ligand-target interaction 143
Identification of alpha(1)-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens 142
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure 142
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol 142
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: The discovery of new functionally selective muscarinic agonists 141
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications 138
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 137
Highly chiral muscarinic ligands: The discovery of (2S,2 ' R,3 ' S,5 ' R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M-2 partial agonist 136
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch 135
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist 132
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 130
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 129
Polyamines may modulate both G protein-coupled receptors and G proteins. 129
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A(2A) and A(2B) receptors ligands 128
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity. 126
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer. 125
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 124
(+)-Cyclazosin derivatives as α1-adrenoceptor antagonists 119
Structure-Activity Relatioships Among Novel Phenoxybenzamine-Related Beta-Chloroethylamines. 118
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists 118
Muscarinic antagonists with multiple stereocenters: Synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl) pyrrolidine sulfoxide derivatives 118
Human adenosine A3 receptor as selective target of new 2-aralkynyl-N6-methyl-MECA derivatives 113
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: Functional evaluation in rat and rabbit tissues 112
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of their iodomethylates. 111
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 105
New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: High affinity ligands for the alpha-adrenoceptor subtypes 101
Innovative functional cAMP assay: application to the pharmacological characterization of GPR17 101
Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward alpha1-Adrenoceptor Subtypes 101
In vitro metabolism studies of new adenosine A(2A) receptor antagonists 100
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives 100
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases 99
Synthesis and α(1)-adrenoceptor antagonist activity of tamsulosin analogues 98
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A(3) receptor 95
Structure-activity relationships among novel phenoxybenzamine-related beta-chloroethylamines 95
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells 95
Purinergic P2X receptors: Structural models and analysis of receptor-ligand interaction 92
Structure-Activity Relationships in 2,2-Diphenyl-2-ethylthioacetic Acid Esters: Unexpected Agonist Activity in a Series of Muscarinic Antagonists. 90
Structure–activity relationships of methoctramine-relatedpolyamines as muscarinic antagonist: Effect of replacing theinner polymethylene chain with cyclic moieties 87
Development of new chromatographic tools based on Adenosine A2A subtype receptor for ligand characterization and screening by FAC-MS 85
Functional cAMP assay optimization at CHO cells expressing A2A adenosine receptors and stably transfected with firefly luciferase biosensor 85
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening 82
New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A2A adenosine receptor antagonists 82
New purine derivatives as P2X3 receptor antagonists 81
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists 81
Existence of snoRNA, microRNA, piRNA characteristics in a novel non-coding RNA: x-ncRNA and its biological implication in Homo sapiens 80
Identification of putative guanosine receptor in rat brain 80
A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity 73
(+)-Cyclazosin Derivatives as alpha1-Adrenoceptor Antagonists 71
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A(1) adenosine receptor antagonists 70
Butter oil (ghee) enrichment with aromatic plants: Chemical characterization and effects on fibroblast migration in an in-vitro wound healing model 70
Anticancer activity study of A3 adenosine receptor agonists 69
GPR17 ligands: synthesis and characterization of new potent agonists 68
Synthesis, Biological Evaluation, and Docking Studies ofTetrahydrofuran- Cyclopentanone- and Cyclopentanol-BasedLigands Acting at Adrenergic α1- and Serotonine 5-HT1A Receptors 66
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Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists 55
Totale 14.008
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Categoria #
all - tutte 57.087
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 57.087
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20203.177 350 148 291 640 189 270 241 289 219 180 138 222
2020/20212.911 146 216 205 224 200 292 530 85 247 173 364 229
2021/20221.424 136 347 40 55 64 48 84 112 105 148 130 155
2022/20231.496 171 93 60 246 149 193 10 98 240 73 120 43
2023/20241.239 161 65 73 49 46 108 63 95 139 43 49 348
2024/2025148 148 0 0 0 0 0 0 0 0 0 0 0
Totale 14.400