BONFILI, Laura
 Distribuzione geografica
Continente #
NA - Nord America 4.923
EU - Europa 3.891
AS - Asia 916
SA - Sud America 14
AF - Africa 11
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 7
Totale 9.770
Nazione #
US - Stati Uniti d'America 4.791
PL - Polonia 1.726
IT - Italia 709
CN - Cina 643
DE - Germania 490
FR - Francia 387
UA - Ucraina 161
GB - Regno Unito 127
CA - Canada 119
SG - Singapore 98
SE - Svezia 87
FI - Finlandia 84
PK - Pakistan 46
VN - Vietnam 39
IE - Irlanda 38
IN - India 23
IR - Iran 20
CZ - Repubblica Ceca 18
BE - Belgio 15
JP - Giappone 15
RU - Federazione Russa 10
CU - Cuba 8
EU - Europa 8
DK - Danimarca 7
ES - Italia 6
KR - Corea 6
NL - Olanda 6
RS - Serbia 6
TH - Thailandia 6
AR - Argentina 5
BR - Brasile 5
MX - Messico 5
AU - Australia 4
GR - Grecia 4
OM - Oman 4
CH - Svizzera 3
DZ - Algeria 3
ET - Etiopia 3
MY - Malesia 3
NZ - Nuova Zelanda 3
PT - Portogallo 3
TR - Turchia 3
EC - Ecuador 2
ID - Indonesia 2
IQ - Iraq 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BD - Bangladesh 1
BG - Bulgaria 1
CL - Cile 1
CO - Colombia 1
EG - Egitto 1
IL - Israele 1
JO - Giordania 1
KE - Kenya 1
LU - Lussemburgo 1
LY - Libia 1
MA - Marocco 1
ME - Montenegro 1
NO - Norvegia 1
PH - Filippine 1
ZA - Sudafrica 1
Totale 9.770
Città #
Warsaw 1.122
Fairfield 635
Kraków 603
Woodbridge 476
Jacksonville 410
Ashburn 384
Houston 324
Chandler 320
Wilmington 268
Ann Arbor 250
Seattle 247
Cambridge 224
Camerino 218
Nanjing 103
Toronto 95
Dearborn 92
New York 67
San Mateo 67
Beijing 65
Lawrence 59
Princeton 59
Ogden 58
Singapore 58
Boardman 55
Helsinki 50
Columbus 46
Nanchang 42
London 38
Dong Ket 37
San Diego 36
Shanghai 36
Dublin 35
Centro 32
Guangzhou 28
Kunming 28
Milan 27
Washington 27
Islamabad 24
Lachine 23
Los Angeles 23
Philadelphia 23
Jiaxing 22
Cesenatico 21
Shenyang 21
Hebei 20
Chicago 19
Brno 16
Nürnberg 16
Redwood City 16
Brussels 15
Hefei 15
Grottammare 14
Tianjin 14
Ardabil 13
Augusta 12
Wuhan 12
Jinan 11
Leawood 11
Bremen 10
Castelraimondo 10
Norwalk 10
Catania 9
Florence 9
Jinhua 9
Lanzhou 9
Tappahannock 9
Havana 8
Multan 8
Perugia 8
Pesaro 8
Phoenix 8
Sakai 8
Yiwu 8
Changsha 7
Fabriano 7
Hangzhou 7
Limbiate 7
Munich 7
Orange 7
Rome 7
Slagelse 7
Zhengzhou 7
Düsseldorf 6
Macerata 6
Ningbo 6
Angri 5
Auburn Hills 5
Lonate Pozzolo 5
Lucknow 5
Seoul 5
Verona 5
Amsterdam 4
Ancona 4
Belgrade 4
Cagliari 4
Cesena 4
Hounslow 4
Kilburn 4
Monmouth Junction 4
Mumbai 4
Totale 7.360
Nome #
A ruthenium derivative of quercetin with enhanced cholesterol-lowering activity 332
Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells 326
SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model 323
Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels 316
Interaction between wheat alpha-amylase/trypsin bi-functional inhibitor and mammalian digestive enzymes: Kinetic, equilibrium and structural characterization of binding 312
Interfering with the high-affinity interaction between wheat amylase trypsin inhibitor CM3 and toll-like receptor 4: in silico and biosensor-based studies 278
The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity 269
Environmental pollutants directly affect the liver X receptor alpha activity: kinetic and thermodynamic characterization of binding 250
Effects of thymoquinone on isolated and cellular proteasomes 234
Wheat sprout extract-induced apoptosis in human cancer cells by proteasomes modulation. 227
Mangiferin blocks proliferation and induces apoptosis of breast cancer cells via suppression of the mevalonate pathway and by proteasome inhibition 220
Arene-Ru(II) complexes of curcumin exert antitumor activity via proteasome inhibition and apoptosis induction 216
Reduction of Alzheimer's disease beta-amyloid pathology by modulating the gut microbiota in a triple transgenic mouse model 214
Wheat sprout extract induces changes on 20S proteasomes functionality. 208
Sanguisorba minor extract suppresses plasmin-mediated mechanisms of cancer cell migration 199
50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems. 197
Essential amino acid mixtures drive cancer cells to apoptosis through proteasome inhibition and autophagy activation 194
The fine-tuning of proteolytic pathways in Alzheimer's disease 189
Wild type and mutant amyloid precursor proteins influence downstream effects of proteasome and autophagy inhibition 188
Amyloid peptides in different assembly states and related effects on isolated and cellular proteasomes 186
Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells. 180
Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer’s disease 175
Natural polyphenols as proteasome modulators and their role as anti-cancer compounds 174
Identification of an EGCG oxidation derivative with proteasome modulatory activity. 174
Binding of aflatoxins to the 20S proteasome: effects on enzyme functionality and implications for oxidative stress and apoptosis 171
Identification of a Killer Toxin from Wickerhamomyces anomalus with β-Glucanase Activity 170
Natural occurring polyphenols as template for drug design. Focus on serine proteases. 167
Ghrelin induces apoptosis in colon adenocarcinoma cells via proteasome inhibition and autophagy induction. 163
Effects of Ghrelin on the Proteolytic Pathways of Alzheimer's Disease Neuronal Cells 157
Arene–Ruthenium(II) Acylpyrazolonato Complexes: Apoptosis-Promoting Effects on Human Cancer Cells 154
Exploring the Molecular Mechanisms Underlying the in vitro Anticancer Effects of Multitarget-Directed Hydrazone Ruthenium(II)-Arene Complexes 153
Crosstalk between the ubiquitin–proteasome system and autophagy in a human cellular model of Alzheimer's disease 149
Chimeric DNA/LNA-based biosensor for the rapid detection of African swine fever virus 149
Dinuclear (h6-arene) ruthenium(II) acylpyrazolone complexes: Synthesis, characterization and cytotoxicity 148
The relationship between the 20S proteasomes and prion-mediated neurodegenerations: potential therapeutic opportunities. 146
Targeting proteasomes with natural occurring compounds in cancer treatment. 143
Ligand Design for N,O- or N,N‐Pyrazolone-Based Hydrazones Ruthenium(II)-Arene Complexes and Investigation of Their Anticancer Activity 136
Mechanistic insights on petrosaspongiolide M inhibitory effects on immunoproteasome and autophagy 134
Guanylin, uroguanylin and guanylate cyclase-C are expressed in the gastrointestinal tract of horses 134
ATP independent proteasomal degradation of NQO1 in BL cell lines 132
Bioactive Ru(II)-Arene Complexes with Natural Polyphenolic Ligands as Anticancer Metallodrugs 127
Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer’s disease: a pre-clinical study 126
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 105
A NEW FAMILIAL LEWY BODY DISEASE IN YELLOW-CROWNED AMAZON PARROTS (AMAZONA OCHROCEPHALA) 100
Novel osmium(ii)–cymene complexes containing curcumin and bisdemethoxycurcumin ligands 100
Probiotic modulation of the microbiota-gut-brain axis: some evidences at different evolutionary levels 93
Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease 92
Characterization of 20S proteasome expression and functionality in brain stem of scrapie sheeps 89
Binuclear 3,3′,5,5′-tetramethyl-1H,H-4,4′-bipyrazole Ruthenium(II) complexes: Synthesis, characterization and biological studies 89
Effect of natural antioxidants on the proteasome functionality. 80
Binding of aflatoxins to the 20S proteasomes: effects on the enzyme functionality 77
Structure/activity virtual screening and in vitro testing of small molecule inhibitors of 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from gut methanogenic bacteria 77
Flavan‐3‐ol Microbial Metabolites Modulate Proteolysis in Neuronal Cells Reducing Amyloid‐beta (1‐42) Levels 74
KLOX FLUORESCENCE BIOMODULATION SYSTEM (KFBS), AN ALTERNATIVE ADJUNCT THERAPY FOR THE MANAGEMENT OF CLINICAL MANIFESTATION OF CANINE PYODERMAS 71
Gut microbiota modulation in Alzheimer's disease: Focus on lipid metabolism 70
Modulation of intracellular proteolytic pathways in neoplastic and neurodegenerative diseases 63
Assessment of serum amyloid A concentrations and biochemical profiles in lactating jennies and newborn Ragusano donkey foals around parturition and one month after foaling in Sicily 62
Arene-ruthenium(II) complexes with tetracyclic oxime derivatives: synthesis, structure and antiproliferative activity against human breast cancer cells 60
Clinical Relevance of Assessing Serum Amyloid and Main Biochemical Parameters in Newborn Ragusano Donkey Foals During the First Month of Life 55
Enhancing the Amyloid-β Anti-Aggregation Properties of Curcumin via Arene-Ruthenium(II) Derivatization 50
Immortalized Alzheimer's Disease Astrocytes: Characterization of Their Proteolytic Systems 46
Targeting Proteolysis with Cyanogenic Glycoside Amygdalin Induces Apoptosis in Breast Cancer Cells 41
Modulation of Gut Microbiota and Neuroprotective Effect of a Yeast‐Enriched Beer 39
Probiotics Supplementation Attenuates Inflammation and Oxidative Stress Induced by Chronic Sleep Restriction 35
Strategic modification of gut microbiota through oral bacteriotherapy influences hypoxia inducible factor-1α: Therapeutic implication in Alzheimer’s disease 35
Gut Microbiome and Mycobiome Alterations in an In Vivo Model of Alzheimer’s Disease 33
Monitoring of biochemical profile and Serum Amyloid A in lactating jennies 30
Homozygous CADPS2 Mutations Cause Neurodegenerative Disease with Lewy Body-like Pathology in Parrots 24
Role of Panax ginseng and ginsenosides in regulating cholesterol homeostasis 21
Bacterial Lysate from the Multi-Strain Probiotic SLAB51 Triggers Adaptative Responses to Hypoxia in Human Caco-2 Intestinal Epithelial Cells under Normoxic Conditions and Attenuates LPS-Induced Inflammatory Response 21
Measuring Biochemical Variables and Serum Amyloid A (SAA) in Working Mules in Central Italy 20
Role of Panax ginseng and ginsenosides in regulating cholesterol homeostasis 18
Microglial polarization differentially affects neuronal vulnerability to the β-amyloid protein: Modulation by melatonin 18
Understanding the Gut-Brain Axis and Its Therapeutic Implications for Neurodegenerative Disorders 15
Ginsenosides Rg1 and Rg2 Activate Autophagy and Attenuate Oxidative Stress in Neuroblastoma Cells Overexpressing Aβ(1-42) 11
Totale 10.054
Categoria #
all - tutte 37.930
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.930


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.935 0 100 200 423 140 186 150 193 183 150 88 122
2020/20211.707 114 130 127 149 146 162 189 51 158 92 260 129
2021/2022853 80 200 41 22 29 19 52 79 50 83 98 100
2022/2023995 124 58 48 161 106 105 16 59 143 79 60 36
2023/20241.061 114 52 90 43 57 166 27 64 94 27 27 300
2024/2025148 91 57 0 0 0 0 0 0 0 0 0 0
Totale 10.054