BONFILI, Laura
 Distribuzione geografica
Continente #
NA - Nord America 5.227
EU - Europa 4.934
AS - Asia 1.251
SA - Sud America 136
AF - Africa 24
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 8
Totale 11.589
Nazione #
US - Stati Uniti d'America 5.090
PL - Polonia 1.726
RU - Federazione Russa 859
IT - Italia 812
CN - Cina 677
DE - Germania 518
FR - Francia 387
SG - Singapore 306
UA - Ucraina 165
GB - Regno Unito 132
CA - Canada 120
BR - Brasile 110
FI - Finlandia 91
SE - Svezia 89
TR - Turchia 68
PK - Pakistan 47
IE - Irlanda 39
VN - Vietnam 39
IN - India 23
IR - Iran 21
NL - Olanda 19
CZ - Repubblica Ceca 18
BE - Belgio 16
JP - Giappone 16
AR - Argentina 9
DK - Danimarca 9
CU - Cuba 8
ES - Italia 8
EU - Europa 8
AT - Austria 7
EG - Egitto 7
MX - Messico 7
RS - Serbia 7
AU - Australia 6
CH - Svizzera 6
EC - Ecuador 6
GR - Grecia 6
KR - Corea 6
TH - Thailandia 6
UZ - Uzbekistan 5
BG - Bulgaria 4
DZ - Algeria 4
IL - Israele 4
IQ - Iraq 4
MA - Marocco 4
OM - Oman 4
PT - Portogallo 4
VE - Venezuela 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
BD - Bangladesh 3
ET - Etiopia 3
HK - Hong Kong 3
KG - Kirghizistan 3
MY - Malesia 3
NZ - Nuova Zelanda 3
BO - Bolivia 2
CL - Cile 2
CO - Colombia 2
HU - Ungheria 2
ID - Indonesia 2
JO - Giordania 2
LU - Lussemburgo 2
NO - Norvegia 2
PA - Panama 2
SK - Slovacchia (Repubblica Slovacca) 2
ZA - Sudafrica 2
AM - Armenia 1
CG - Congo 1
IS - Islanda 1
KE - Kenya 1
LT - Lituania 1
LV - Lettonia 1
LY - Libia 1
ME - Montenegro 1
PE - Perù 1
PH - Filippine 1
SA - Arabia Saudita 1
TN - Tunisia 1
Totale 11.589
Città #
Warsaw 1.122
Fairfield 635
Kraków 603
Woodbridge 476
Jacksonville 410
Ashburn 398
Houston 324
Chandler 320
Camerino 275
Wilmington 268
Ann Arbor 250
Seattle 247
Cambridge 224
Boardman 205
Singapore 131
Nanjing 103
Toronto 95
Dearborn 92
New York 68
San Mateo 67
Beijing 65
Istanbul 62
Lawrence 59
Princeton 59
Ogden 58
Helsinki 55
Columbus 46
Nanchang 43
London 38
Moscow 38
Dong Ket 37
Los Angeles 37
Dublin 36
San Diego 36
Shanghai 36
Centro 32
Milan 32
Guangzhou 28
Kunming 28
Washington 27
Islamabad 25
Jiaxing 23
Lachine 23
Philadelphia 23
Munich 22
Shenyang 22
Cesenatico 21
Hebei 20
Chicago 19
Rome 17
Brno 16
Brussels 16
Council Bluffs 16
Nürnberg 16
Redwood City 16
Hefei 15
Grottammare 14
Tianjin 14
Ardabil 13
Augusta 12
Wuhan 12
Jinan 11
Leawood 11
São Paulo 11
Bremen 10
Castelraimondo 10
Lanzhou 10
Norwalk 10
Catania 9
Changsha 9
Florence 9
Jinhua 9
Nuremberg 9
Perugia 9
Tappahannock 9
Zhengzhou 9
Havana 8
Multan 8
Pesaro 8
Phoenix 8
Sakai 8
Yiwu 8
Fabriano 7
Hangzhou 7
Limbiate 7
Orange 7
Slagelse 7
Düsseldorf 6
Macerata 6
Ningbo 6
Angri 5
Auburn Hills 5
Belgrade 5
Cairo 5
Lonate Pozzolo 5
Lucknow 5
Seoul 5
Stockbridge 5
Tashkent 5
Verona 5
Totale 7.836
Nome #
A ruthenium derivative of quercetin with enhanced cholesterol-lowering activity 375
SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model 354
Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells 351
Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels 340
Interaction between wheat alpha-amylase/trypsin bi-functional inhibitor and mammalian digestive enzymes: Kinetic, equilibrium and structural characterization of binding 326
Interfering with the high-affinity interaction between wheat amylase trypsin inhibitor CM3 and toll-like receptor 4: in silico and biosensor-based studies 301
The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity 286
Environmental pollutants directly affect the liver X receptor alpha activity: kinetic and thermodynamic characterization of binding 279
Effects of thymoquinone on isolated and cellular proteasomes 260
Wheat sprout extract-induced apoptosis in human cancer cells by proteasomes modulation. 249
Arene-Ru(II) complexes of curcumin exert antitumor activity via proteasome inhibition and apoptosis induction 243
Mangiferin blocks proliferation and induces apoptosis of breast cancer cells via suppression of the mevalonate pathway and by proteasome inhibition 233
Reduction of Alzheimer's disease beta-amyloid pathology by modulating the gut microbiota in a triple transgenic mouse model 233
50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems. 231
Wheat sprout extract induces changes on 20S proteasomes functionality. 230
Amyloid peptides in different assembly states and related effects on isolated and cellular proteasomes 223
Essential amino acid mixtures drive cancer cells to apoptosis through proteasome inhibition and autophagy activation 219
Sanguisorba minor extract suppresses plasmin-mediated mechanisms of cancer cell migration 214
Binding of aflatoxins to the 20S proteasome: effects on enzyme functionality and implications for oxidative stress and apoptosis 210
The fine-tuning of proteolytic pathways in Alzheimer's disease 203
Wild type and mutant amyloid precursor proteins influence downstream effects of proteasome and autophagy inhibition 201
Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer’s disease 199
Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells. 197
Identification of a Killer Toxin from Wickerhamomyces anomalus with β-Glucanase Activity 193
Natural polyphenols as proteasome modulators and their role as anti-cancer compounds 189
Identification of an EGCG oxidation derivative with proteasome modulatory activity. 189
Crosstalk between the ubiquitin–proteasome system and autophagy in a human cellular model of Alzheimer's disease 185
Effects of Ghrelin on the Proteolytic Pathways of Alzheimer's Disease Neuronal Cells 185
Ghrelin induces apoptosis in colon adenocarcinoma cells via proteasome inhibition and autophagy induction. 184
Chimeric DNA/LNA-based biosensor for the rapid detection of African swine fever virus 184
Natural occurring polyphenols as template for drug design. Focus on serine proteases. 183
Arene–Ruthenium(II) Acylpyrazolonato Complexes: Apoptosis-Promoting Effects on Human Cancer Cells 183
Exploring the Molecular Mechanisms Underlying the in vitro Anticancer Effects of Multitarget-Directed Hydrazone Ruthenium(II)-Arene Complexes 182
Dinuclear (h6-arene) ruthenium(II) acylpyrazolone complexes: Synthesis, characterization and cytotoxicity 170
Targeting proteasomes with natural occurring compounds in cancer treatment. 159
Bioactive Ru(II)-Arene Complexes with Natural Polyphenolic Ligands as Anticancer Metallodrugs 159
ATP independent proteasomal degradation of NQO1 in BL cell lines 159
Guanylin, uroguanylin and guanylate cyclase-C are expressed in the gastrointestinal tract of horses 156
The relationship between the 20S proteasomes and prion-mediated neurodegenerations: potential therapeutic opportunities. 155
Ligand Design for N,O- or N,N‐Pyrazolone-Based Hydrazones Ruthenium(II)-Arene Complexes and Investigation of Their Anticancer Activity 151
Mechanistic insights on petrosaspongiolide M inhibitory effects on immunoproteasome and autophagy 146
Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer’s disease: a pre-clinical study 146
A NEW FAMILIAL LEWY BODY DISEASE IN YELLOW-CROWNED AMAZON PARROTS (AMAZONA OCHROCEPHALA) 138
Binuclear 3,3′,5,5′-tetramethyl-1H,H-4,4′-bipyrazole Ruthenium(II) complexes: Synthesis, characterization and biological studies 128
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 126
Characterization of 20S proteasome expression and functionality in brain stem of scrapie sheeps 113
Probiotic modulation of the microbiota-gut-brain axis: some evidences at different evolutionary levels 113
Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease 113
Binding of aflatoxins to the 20S proteasomes: effects on the enzyme functionality 112
Novel osmium(ii)–cymene complexes containing curcumin and bisdemethoxycurcumin ligands 112
Structure/activity virtual screening and in vitro testing of small molecule inhibitors of 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from gut methanogenic bacteria 109
Effect of natural antioxidants on the proteasome functionality. 101
Assessment of serum amyloid A concentrations and biochemical profiles in lactating jennies and newborn Ragusano donkey foals around parturition and one month after foaling in Sicily 97
Flavan‐3‐ol Microbial Metabolites Modulate Proteolysis in Neuronal Cells Reducing Amyloid‐beta (1‐42) Levels 96
KLOX FLUORESCENCE BIOMODULATION SYSTEM (KFBS), AN ALTERNATIVE ADJUNCT THERAPY FOR THE MANAGEMENT OF CLINICAL MANIFESTATION OF CANINE PYODERMAS 95
Arene-ruthenium(II) complexes with tetracyclic oxime derivatives: synthesis, structure and antiproliferative activity against human breast cancer cells 94
Gut microbiota modulation in Alzheimer's disease: Focus on lipid metabolism 91
Clinical Relevance of Assessing Serum Amyloid and Main Biochemical Parameters in Newborn Ragusano Donkey Foals During the First Month of Life 87
Enhancing the Amyloid-β Anti-Aggregation Properties of Curcumin via Arene-Ruthenium(II) Derivatization 76
Modulation of intracellular proteolytic pathways in neoplastic and neurodegenerative diseases 72
Immortalized Alzheimer's Disease Astrocytes: Characterization of Their Proteolytic Systems 71
Role of Panax ginseng and ginsenosides in regulating cholesterol homeostasis 63
Targeting Proteolysis with Cyanogenic Glycoside Amygdalin Induces Apoptosis in Breast Cancer Cells 59
Probiotics Supplementation Attenuates Inflammation and Oxidative Stress Induced by Chronic Sleep Restriction 59
Modulation of Gut Microbiota and Neuroprotective Effect of a Yeast‐Enriched Beer 59
Role of Panax ginseng and ginsenosides in regulating cholesterol homeostasis 57
Gut Microbiome and Mycobiome Alterations in an In Vivo Model of Alzheimer’s Disease 57
Homozygous CADPS2 Mutations Cause Neurodegenerative Disease with Lewy Body-like Pathology in Parrots 55
Strategic modification of gut microbiota through oral bacteriotherapy influences hypoxia inducible factor-1α: Therapeutic implication in Alzheimer’s disease 53
Monitoring of biochemical profile and Serum Amyloid A in lactating jennies 52
Bacterial Lysate from the Multi-Strain Probiotic SLAB51 Triggers Adaptative Responses to Hypoxia in Human Caco-2 Intestinal Epithelial Cells under Normoxic Conditions and Attenuates LPS-Induced Inflammatory Response 50
Measuring Biochemical Variables and Serum Amyloid A (SAA) in Working Mules in Central Italy 45
Ginsenosides Rg1 and Rg2 Activate Autophagy and Attenuate Oxidative Stress in Neuroblastoma Cells Overexpressing Aβ(1-42) 40
Microglial polarization differentially affects neuronal vulnerability to the β-amyloid protein: Modulation by melatonin 34
Understanding the Gut-Brain Axis and Its Therapeutic Implications for Neurodegenerative Disorders 30
Electrospinning and Electrospraying: Emerging Techniques for Probiotic Stabilization and Application 17
Development of sugar- and fat-reduced pulse cookies with improved predicted glycemic behavior 6
Totale 11.895
Categoria #
all - tutte 46.384
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.384


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020543 0 0 0 0 0 0 0 0 183 150 88 122
2020/20211.707 114 130 127 149 146 162 189 51 158 92 260 129
2021/2022853 80 200 41 22 29 19 52 79 50 83 98 100
2022/2023995 124 58 48 161 106 105 16 59 143 79 60 36
2023/20241.061 114 52 90 43 57 166 27 64 94 27 27 300
2024/20251.989 91 57 219 121 85 124 366 718 208 0 0 0
Totale 11.895