QUAGLIA, Wilma
 Distribuzione geografica
Continente #
NA - Nord America 11.288
EU - Europa 4.674
AS - Asia 2.542
SA - Sud America 50
Continente sconosciuto - Info sul continente non disponibili 47
AF - Africa 15
OC - Oceania 15
Totale 18.631
Nazione #
US - Stati Uniti d'America 10.915
CN - Cina 1.892
DE - Germania 1.178
IT - Italia 1.122
UA - Ucraina 459
SE - Svezia 426
CA - Canada 367
SG - Singapore 344
PL - Polonia 321
GB - Regno Unito 308
FI - Finlandia 295
FR - Francia 180
TR - Turchia 143
IE - Irlanda 122
CZ - Repubblica Ceca 82
BE - Belgio 53
EU - Europa 45
IN - India 30
NL - Olanda 29
IR - Iran 26
RU - Federazione Russa 26
VN - Vietnam 24
BR - Brasile 23
AU - Australia 15
PK - Pakistan 15
RO - Romania 15
JP - Giappone 13
EG - Egitto 11
HR - Croazia 10
KR - Corea 8
PE - Perù 8
GR - Grecia 7
PT - Portogallo 7
UY - Uruguay 7
RS - Serbia 6
CL - Cile 5
HK - Hong Kong 5
LT - Lituania 5
AE - Emirati Arabi Uniti 4
ID - Indonesia 4
IQ - Iraq 4
KH - Cambogia 4
MY - Malesia 4
AZ - Azerbaigian 3
BG - Bulgaria 3
CH - Svizzera 3
CO - Colombia 3
ES - Italia 3
IL - Israele 3
KG - Kirghizistan 3
MX - Messico 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AR - Argentina 2
BY - Bielorussia 2
DK - Danimarca 2
DZ - Algeria 2
HU - Ungheria 2
IS - Islanda 2
LV - Lettonia 2
NO - Norvegia 2
PA - Panama 2
PH - Filippine 2
PS - Palestinian Territory 2
TH - Thailandia 2
VE - Venezuela 2
AM - Armenia 1
AT - Austria 1
EE - Estonia 1
GE - Georgia 1
JM - Giamaica 1
MA - Marocco 1
MN - Mongolia 1
QA - Qatar 1
SA - Arabia Saudita 1
TW - Taiwan 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 18.631
Città #
Woodbridge 1.178
Jacksonville 1.136
Fairfield 1.048
Chandler 879
Ann Arbor 682
Ashburn 649
Houston 643
Wilmington 603
Boardman 488
Seattle 432
Nanjing 380
Cambridge 320
Toronto 271
Dearborn 242
Singapore 241
Camerino 232
Warsaw 179
San Mateo 178
Düsseldorf 177
Beijing 171
Lawrence 157
Princeton 157
Helsinki 151
Nanchang 140
Kraków 138
Columbus 126
Dublin 122
Istanbul 120
Ogden 119
Kunming 98
Shanghai 94
Lachine 92
Shenyang 85
London 84
Los Angeles 69
Jiaxing 65
Brno 63
Guangzhou 62
Tianjin 61
Hebei 54
Jinan 54
New York 54
Brussels 51
Venezia 51
San Diego 48
Changsha 46
Milan 44
Munich 43
Hangzhou 39
Philadelphia 39
Redwood City 37
Wuhan 32
Nürnberg 31
Zhengzhou 31
Bremen 29
Falls Church 27
Washington 27
Leawood 26
Ningbo 26
Hefei 25
Venice 25
Taizhou 24
Chicago 22
Orange 21
Verona 21
Monmouth Junction 19
Old Bridge 19
Centro 18
Dong Ket 17
Kocaeli 17
Olomouc 17
Perugia 17
Fuzhou 16
Dronten 14
Lanzhou 14
Strasbourg 14
Ardabil 13
Augusta 13
Buffalo 13
Espoo 13
Yiwu 13
Auburn Hills 12
Jinhua 12
Nantong 12
Tulsa 12
Buti 11
Changchun 11
Hanover 11
Horia 11
Indiana 11
Lahore 11
Pesaro 11
Tappahannock 11
Baotou 9
Frankfurt am Main 9
Norwalk 9
Berlin 8
Council Bluffs 8
Lima 8
Mountain View 8
Totale 13.501
Nome #
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 267
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 265
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 249
Hyperphagic effect of novel compounds with high affinity for imidazoline I2 binding sites 240
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 240
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor 234
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring 230
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 208
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 208
Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity 205
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 198
1,4-Dioxane nucleus as a suitable scaffold in the building of ligands interacting with NMDA and σ1 receptors 196
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 193
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 193
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 188
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 185
Nano-medicine improving the bioavailability of small molecules for the prevention of neurodegenerative diseases 179
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 173
Discovery of Highly Selective Imidazoline Receptor Ligands 169
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 169
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 165
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 164
null 162
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 161
Structure-activity relationships among benextramine-related tetraamine disulfides at peripheral alpha-adrenoreceptors 160
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 160
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 157
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 156
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane 156
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites 154
Roles of Wnt/β-catenin signalling pathway in the bony repair of injured growth plate cartilage in young rats 153
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 149
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 148
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 148
Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1‑[3- (4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77- LH-28-1) 148
Dopamine D-5 receptors: A challenge to medicinal chemists 147
Synthesis and cytotoxic activity evaluation of new Cu(I) complexes of bis(pyrazol-1-yl) acetate ligands functionalized with an NMDA receptor antagonist 147
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 145
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 145
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 144
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 144
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 144
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 141
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 141
Muscarinic Thioligands with Cyclopentane Nucleus 141
Chain-lengthened and imidazoline analogues of nicotine 140
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca2+-activated K+ permeability of erythrocytes 140
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 140
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 140
Structure-activity relationships in prazosin-related compounds. Effect of replacing a piperazine ring with an alkanediamine moiety on alpha1- adrenoreceptorblocking activity. 139
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 138
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 135
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 135
Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells 135
Structure-activity relationships among benextramine-related tetraamine disulfides. Chain length effect on alpha-adrenoreceptor blocking activity1 134
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 134
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 133
Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors 132
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 130
Synthesis and Structure-Activity Relationship Studies in a Series of 2-Substituted 1,3-Dioxolanes Modified at the Cationic Head. 130
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 129
null 129
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 128
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 127
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 125
I1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells. 123
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 122
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 119
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 118
Rational design and biological evaluation of novel conjugated heteroscorpionate ligands and related Copper(I/II) complexes 118
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 117
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 115
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 115
Search for selective antagonists at alpha1-adrenoreceptors: neutral or negative antagonism? 115
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 114
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 111
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 110
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 110
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 109
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 109
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 109
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 107
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 107
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 107
I recettori adrenergici 106
Synthesis and Muscarinic Receptors Affinity of a series of Antagonist Bivalent Ligands 106
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 106
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 4. Effect of aryl and alkyl Substituents at Position 3 on α-adrenoreceptor blocking activity 106
Antimuscarinic activity in a series of 2-substituted 1,3-dioxolanes 105
Rational design of novel I1-imidazoline receptor agonists 103
GluN2B-Selective N-Methyl-d-aspartate (NMDA) Receptor Antagonists Derived from 3-Benzazepines: Synthesis and Pharmacological Evaluation of Benzo[7]annulen-7-amines 103
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 103
Molecular determinants in the binding of novel 1,4-benzodioxan-related α1D-adrenergic receptor antagonists: a computational study 102
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 102
Imidazoline nucleus as a biologically versatile scaffold 100
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 100
Fluoronorepinephrines: further pharmacological evaluation in vitro and inpithed rats 99
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 97
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 97
Structure-Activity Relationships in 1,4-Benzodioxan-Related Compounds. 6. Role of the Dioxane Unit on Selectivity for Alpha1-Adrenoreceptor Subtypes 96
Totale 14.428
Categoria #
all - tutte 79.984
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.984


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.856 0 0 0 0 0 407 358 350 211 216 87 227
2020/20212.850 149 265 221 279 185 163 367 80 233 128 515 265
2021/20221.729 135 408 28 117 134 88 47 119 134 198 119 202
2022/20232.361 284 70 117 328 268 315 17 137 429 130 170 96
2023/20241.698 221 100 128 57 70 151 74 48 183 68 42 556
2024/20251.337 259 127 465 263 176 47 0 0 0 0 0 0
Totale 19.035