QUAGLIA, Wilma
 Distribuzione geografica
Continente #
NA - Nord America 17.660
EU - Europa 7.862
AS - Asia 7.025
SA - Sud America 814
Continente sconosciuto - Info sul continente non disponibili 495
AF - Africa 269
OC - Oceania 54
Totale 34.179
Nazione #
US - Stati Uniti d'America 17.068
CN - Cina 2.853
SG - Singapore 2.081
RU - Federazione Russa 1.807
IT - Italia 1.544
DE - Germania 1.353
BR - Brasile 670
VN - Vietnam 574
HK - Hong Kong 545
GB - Regno Unito 478
UA - Ucraina 473
CA - Canada 472
SE - Svezia 463
FR - Francia 412
FI - Finlandia 401
PL - Polonia 388
TR - Turchia 199
ZA - Sudafrica 185
KR - Corea 177
IN - India 148
IE - Irlanda 131
BD - Bangladesh 95
CZ - Repubblica Ceca 85
JP - Giappone 82
NL - Olanda 74
MX - Messico 73
BE - Belgio 60
AU - Australia 51
AR - Argentina 50
ES - Italia 45
EU - Europa 45
PK - Pakistan 40
IQ - Iraq 36
IR - Iran 36
EG - Egitto 30
EC - Ecuador 26
LT - Lituania 20
RO - Romania 18
AT - Austria 17
CO - Colombia 16
AE - Emirati Arabi Uniti 15
HR - Croazia 15
MY - Malesia 15
ID - Indonesia 14
SA - Arabia Saudita 14
MA - Marocco 13
PE - Perù 13
UY - Uruguay 12
VE - Venezuela 12
CH - Svizzera 11
PH - Filippine 11
DZ - Algeria 10
PT - Portogallo 10
GR - Grecia 9
JM - Giamaica 9
KE - Kenya 9
NP - Nepal 9
TW - Taiwan 9
CL - Cile 8
RS - Serbia 8
UZ - Uzbekistan 8
AL - Albania 7
JO - Giordania 7
AZ - Azerbaigian 6
DO - Repubblica Dominicana 6
HN - Honduras 6
IL - Israele 6
KH - Cambogia 6
PA - Panama 6
PY - Paraguay 6
TH - Thailandia 6
BG - Bulgaria 5
BY - Bielorussia 5
KG - Kirghizistan 5
NI - Nicaragua 5
PS - Palestinian Territory 5
TN - Tunisia 5
CR - Costa Rica 4
HU - Ungheria 4
LV - Lettonia 4
SN - Senegal 4
TT - Trinidad e Tobago 4
GA - Gabon 3
GT - Guatemala 3
IS - Islanda 3
KZ - Kazakistan 3
LB - Libano 3
OM - Oman 3
QA - Qatar 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
DK - Danimarca 2
GE - Georgia 2
GH - Ghana 2
LA - Repubblica Popolare Democratica del Laos 2
MK - Macedonia 2
MT - Malta 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
AD - Andorra 1
Totale 33.709
Città #
Dallas 1.346
Ashburn 1.331
Woodbridge 1.178
Jacksonville 1.139
Singapore 1.120
Fairfield 1.048
Chandler 879
San Jose 777
Ann Arbor 683
Houston 666
Council Bluffs 621
Wilmington 605
Hong Kong 533
Beijing 489
Boardman 487
Seattle 443
Nanjing 380
Cambridge 321
Los Angeles 307
Toronto 290
Camerino 273
Dearborn 242
Warsaw 238
New York 237
The Dalles 231
Ho Chi Minh City 202
Helsinki 192
Düsseldorf 186
San Mateo 178
Seoul 171
Johannesburg 169
Tongling 165
Lawrence 157
Princeton 157
Lauterbourg 150
Columbus 141
Istanbul 141
Nanchang 141
Kraków 138
Moscow 134
Munich 134
Dublin 130
Santa Clara 129
Hanoi 128
Buffalo 120
Ogden 119
Orem 114
London 106
Shanghai 102
Kunming 98
Lachine 92
Milan 91
Shenyang 87
São Paulo 74
Guangzhou 69
Jiaxing 66
Tokyo 64
Brno 63
Tianjin 63
Turku 61
Chicago 59
Brussels 57
Chennai 55
Jinan 55
Hebei 54
Rome 54
Frankfurt am Main 52
Venezia 51
San Diego 50
Changsha 48
Hangzhou 48
Philadelphia 43
Brooklyn 42
Manchester 42
Montreal 41
Trieste 41
Poplar 40
Stockholm 39
Phoenix 38
Redwood City 37
St Louis 37
Zhengzhou 37
Denver 36
Mexico City 34
Wuhan 34
Washington 33
Ascoli Piceno 31
Nürnberg 31
Boston 30
Da Nang 30
Atlanta 29
Bremen 29
Amsterdam 28
Venice 28
Falls Church 27
Hefei 26
Leawood 26
Ningbo 26
Mumbai 24
Nuremberg 24
Totale 21.742
Nome #
1,4-Dioxane nucleus as a suitable scaffold in the building of ligands interacting with NMDA and σ1 receptors 655
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 632
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 629
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 564
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 558
Roles of Wnt/β-catenin signalling pathway in the bony repair of injured growth plate cartilage in young rats 467
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 344
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 336
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor 331
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 330
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring 310
Hyperphagic effect of novel compounds with high affinity for imidazoline I2 binding sites 307
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 303
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 294
Nano-medicine improving the bioavailability of small molecules for the prevention of neurodegenerative diseases 278
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 273
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 271
Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity 268
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 266
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane 262
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 254
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 252
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 246
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 244
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 240
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 239
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 234
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites 230
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 230
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 228
Discovery of Highly Selective Imidazoline Receptor Ligands 227
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 225
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 223
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 222
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 221
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 221
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 220
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 218
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 217
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 215
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 214
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 213
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 213
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 212
Dopamine D-5 receptors: A challenge to medicinal chemists 212
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 211
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 208
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 208
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 207
Structure-activity relationships among benextramine-related tetraamine disulfides at peripheral alpha-adrenoreceptors 207
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 207
Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells 207
Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders 205
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 205
Search for selective antagonists at alpha1-adrenoreceptors: neutral or negative antagonism? 205
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 204
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 203
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 202
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 201
4WD to Travel Inside the 5-HT1A Receptor World 201
Antimuscarinic activity in a series of 2-substituted 1,3-dioxolanes 200
Synthesis and cytotoxic activity evaluation of new Cu(I) complexes of bis(pyrazol-1-yl) acetate ligands functionalized with an NMDA receptor antagonist 200
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 196
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 195
Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1‑[3- (4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77- LH-28-1) 195
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 194
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 194
Chain-lengthened and imidazoline analogues of nicotine 192
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 192
Muscarinic Thioligands with Cyclopentane Nucleus 192
Rational design and biological evaluation of novel conjugated heteroscorpionate ligands and related Copper(I/II) complexes 192
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 191
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 189
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 189
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca2+-activated K+ permeability of erythrocytes 188
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 186
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 185
Synthesis and Structure-Activity Relationship Studies in a Series of 2-Substituted 1,3-Dioxolanes Modified at the Cationic Head. 185
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 185
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 184
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 184
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 183
Structure-activity relationships in prazosin-related compounds. Effect of replacing a piperazine ring with an alkanediamine moiety on alpha1- adrenoreceptorblocking activity. 183
Novel highly potent and selective sigma1 receptor antagonists effectively block the binge eating episode in female rats 182
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 181
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 180
Assessing the role of ghrelin and the enzyme ghrelin O-acyltransferase (GOAT) system in food reward, food motivation, and binge eating behavior 179
Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor 179
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 178
Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors 177
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 176
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 176
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 176
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 175
Structure-activity relationships among benextramine-related tetraamine disulfides. Chain length effect on alpha-adrenoreceptor blocking activity1 174
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 174
Rational design of novel I1-imidazoline receptor agonists 173
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 172
Advances in drug design and therapeutic potential of selective or multitarget 5‐HT1A receptor ligands 170
GluN2B-Selective N-Methyl-d-aspartate (NMDA) Receptor Antagonists Derived from 3-Benzazepines: Synthesis and Pharmacological Evaluation of Benzo[7]annulen-7-amines 170
Totale 23.795
Categoria #
all - tutte 131.750
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 131.750


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.594 0 408 28 117 134 88 47 119 134 198 119 202
2022/20232.361 284 70 117 328 268 315 17 137 429 130 170 96
2023/20241.698 221 100 128 57 70 151 74 48 183 68 42 556
2024/20255.664 259 125 462 263 174 323 653 1.338 439 363 380 885
2025/20269.860 547 612 1.678 1.299 972 675 1.344 634 570 639 539 351
2026/2027957 740 217 0 0 0 0 0 0 0 0 0 0
Totale 34.179