QUAGLIA, Wilma
 Distribuzione geografica
Continente #
NA - Nord America 16.150
EU - Europa 7.775
AS - Asia 6.708
SA - Sud America 800
AF - Africa 268
OC - Oceania 54
Continente sconosciuto - Info sul continente non disponibili 47
Totale 31.802
Nazione #
US - Stati Uniti d'America 15.610
CN - Cina 2.716
SG - Singapore 1.980
RU - Federazione Russa 1.820
IT - Italia 1.462
DE - Germania 1.353
BR - Brasile 666
VN - Vietnam 572
HK - Hong Kong 540
GB - Regno Unito 478
UA - Ucraina 473
SE - Svezia 462
CA - Canada 446
FR - Francia 410
FI - Finlandia 402
PL - Polonia 387
TR - Turchia 199
ZA - Sudafrica 186
KR - Corea 174
IN - India 147
IE - Irlanda 130
CZ - Repubblica Ceca 85
JP - Giappone 77
NL - Olanda 70
MX - Messico 61
BE - Belgio 60
AU - Australia 51
AR - Argentina 50
BD - Bangladesh 50
EU - Europa 45
ES - Italia 42
PK - Pakistan 39
IQ - Iraq 36
IR - Iran 36
EG - Egitto 30
EC - Ecuador 24
LT - Lituania 21
AT - Austria 17
RO - Romania 17
HR - Croazia 15
AE - Emirati Arabi Uniti 14
SA - Arabia Saudita 14
MA - Marocco 13
PE - Perù 13
CO - Colombia 12
ID - Indonesia 12
PH - Filippine 11
UY - Uruguay 11
VE - Venezuela 11
DZ - Algeria 10
GR - Grecia 9
PT - Portogallo 9
TW - Taiwan 9
CH - Svizzera 8
CL - Cile 8
KE - Kenya 8
MY - Malesia 8
RS - Serbia 8
UZ - Uzbekistan 8
AL - Albania 7
JO - Giordania 7
AZ - Azerbaigian 6
IL - Israele 6
JM - Giamaica 6
KH - Cambogia 6
PA - Panama 6
BY - Bielorussia 5
DO - Repubblica Dominicana 5
KG - Kirghizistan 5
NP - Nepal 5
PS - Palestinian Territory 5
TH - Thailandia 5
HU - Ungheria 4
LV - Lettonia 4
PY - Paraguay 4
SN - Senegal 4
TN - Tunisia 4
BG - Bulgaria 3
GA - Gabon 3
HN - Honduras 3
IS - Islanda 3
KZ - Kazakistan 3
LB - Libano 3
NI - Nicaragua 3
OM - Oman 3
QA - Qatar 3
TT - Trinidad e Tobago 3
A2 - ???statistics.table.value.countryCode.A2??? 2
CR - Costa Rica 2
DK - Danimarca 2
GE - Georgia 2
GH - Ghana 2
GT - Guatemala 2
MT - Malta 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
AD - Andorra 1
AM - Armenia 1
AO - Angola 1
BH - Bahrain 1
Totale 31.781
Città #
Dallas 1.332
Ashburn 1.269
Woodbridge 1.178
Jacksonville 1.137
Singapore 1.093
Fairfield 1.048
Chandler 879
San Jose 707
Ann Arbor 682
Houston 661
Wilmington 604
Hong Kong 528
Boardman 488
Beijing 463
Seattle 441
Nanjing 380
Cambridge 321
Los Angeles 289
Toronto 288
Camerino 271
Dearborn 242
Warsaw 238
The Dalles 219
New York 211
Ho Chi Minh City 203
Helsinki 193
Düsseldorf 186
San Mateo 178
Johannesburg 170
Seoul 170
Tongling 166
Lawrence 157
Princeton 157
Lauterbourg 150
Columbus 141
Istanbul 141
Nanchang 140
Kraków 138
Moscow 134
Munich 134
Dublin 130
Hanoi 127
Ogden 119
Buffalo 114
Orem 109
London 106
Shanghai 99
Kunming 98
Lachine 92
Santa Clara 91
Milan 90
Shenyang 87
São Paulo 74
Guangzhou 69
Jiaxing 66
Brno 63
Tianjin 63
Tokyo 62
Turku 61
Brussels 57
Chicago 57
Chennai 55
Jinan 55
Hebei 54
Council Bluffs 52
Frankfurt am Main 52
Rome 51
Venezia 51
San Diego 49
Changsha 48
Hangzhou 43
Manchester 42
Trieste 42
Poplar 41
Philadelphia 40
Stockholm 39
Brooklyn 37
Redwood City 37
Zhengzhou 36
Montreal 35
Wuhan 33
Denver 32
Nürnberg 31
Da Nang 30
Washington 30
Boston 29
Bremen 29
Amsterdam 28
Venice 28
Ascoli Piceno 27
Falls Church 27
Hefei 26
Leawood 26
Ningbo 26
Atlanta 25
Mumbai 24
Nuremberg 24
Taizhou 24
Haiphong 23
Mexico City 23
Totale 20.765
Nome #
1,4-Dioxane nucleus as a suitable scaffold in the building of ligands interacting with NMDA and σ1 receptors 627
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 615
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 615
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 551
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 548
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 330
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 327
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor 326
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring 303
Hyperphagic effect of novel compounds with high affinity for imidazoline I2 binding sites 302
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 294
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 290
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 267
Nano-medicine improving the bioavailability of small molecules for the prevention of neurodegenerative diseases 267
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 264
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 264
Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity 262
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 255
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane 253
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 246
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 240
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 238
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 238
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 234
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 234
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 226
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites 225
Discovery of Highly Selective Imidazoline Receptor Ligands 221
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 218
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 218
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 216
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 216
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 216
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 213
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 209
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 209
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 208
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 208
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 207
Dopamine D-5 receptors: A challenge to medicinal chemists 207
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 206
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 206
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 205
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 204
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 203
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 202
Structure-activity relationships among benextramine-related tetraamine disulfides at peripheral alpha-adrenoreceptors 202
Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells 202
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 200
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 199
Search for selective antagonists at alpha1-adrenoreceptors: neutral or negative antagonism? 198
Roles of Wnt/β-catenin signalling pathway in the bony repair of injured growth plate cartilage in young rats 197
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 196
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 195
Synthesis and cytotoxic activity evaluation of new Cu(I) complexes of bis(pyrazol-1-yl) acetate ligands functionalized with an NMDA receptor antagonist 195
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 194
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 194
4WD to Travel Inside the 5-HT1A Receptor World 193
Antimuscarinic activity in a series of 2-substituted 1,3-dioxolanes 192
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 192
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 191
Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1‑[3- (4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77- LH-28-1) 190
Rational design and biological evaluation of novel conjugated heteroscorpionate ligands and related Copper(I/II) complexes 189
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 188
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 187
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 186
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 186
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 185
Muscarinic Thioligands with Cyclopentane Nucleus 185
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca2+-activated K+ permeability of erythrocytes 183
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 183
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 183
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 179
Chain-lengthened and imidazoline analogues of nicotine 179
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 179
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 178
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 178
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 178
Structure-activity relationships in prazosin-related compounds. Effect of replacing a piperazine ring with an alkanediamine moiety on alpha1- adrenoreceptorblocking activity. 177
Synthesis and Structure-Activity Relationship Studies in a Series of 2-Substituted 1,3-Dioxolanes Modified at the Cationic Head. 177
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 177
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 176
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 175
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 173
Structure-activity relationships among benextramine-related tetraamine disulfides. Chain length effect on alpha-adrenoreceptor blocking activity1 172
Novel highly potent and selective sigma1 receptor antagonists effectively block the binge eating episode in female rats 172
Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors 171
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 170
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 169
Rational design of novel I1-imidazoline receptor agonists 168
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 168
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 167
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 165
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 164
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 163
null 162
Assessing the role of ghrelin and the enzyme ghrelin O-acyltransferase (GOAT) system in food reward, food motivation, and binge eating behavior 162
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 161
I recettori adrenergici 161
Adrenoceptors as targets in drug discovery: Medicinal chemistry and therapeutical potential 160
Totale 22.599
Categoria #
all - tutte 120.020
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 120.020


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021908 0 0 0 0 0 0 0 0 0 128 515 265
2021/20221.729 135 408 28 117 134 88 47 119 134 198 119 202
2022/20232.361 284 70 117 328 268 315 17 137 429 130 170 96
2023/20241.698 221 100 128 57 70 151 74 48 183 68 42 556
2024/20255.708 259 127 465 263 176 324 657 1.348 443 364 382 900
2025/20268.837 549 613 1.680 1.310 974 678 1.352 637 574 470 0 0
Totale 32.243