QUAGLIA, Wilma
 Distribuzione geografica
Continente #
NA - Nord America 19.319
EU - Europa 7.966
AS - Asia 7.062
SA - Sud America 855
Continente sconosciuto - Info sul continente non disponibili 495
AF - Africa 272
OC - Oceania 56
Totale 36.025
Nazione #
US - Stati Uniti d'America 18.651
CN - Cina 2.861
SG - Singapore 2.085
RU - Federazione Russa 1.809
IT - Italia 1.607
DE - Germania 1.355
BR - Brasile 703
VN - Vietnam 574
HK - Hong Kong 546
CA - Canada 521
GB - Regno Unito 494
UA - Ucraina 473
SE - Svezia 463
FR - Francia 420
FI - Finlandia 401
PL - Polonia 388
TR - Turchia 199
ZA - Sudafrica 185
KR - Corea 178
IN - India 149
IE - Irlanda 133
BD - Bangladesh 102
CZ - Repubblica Ceca 85
JP - Giappone 83
MX - Messico 75
NL - Olanda 74
BE - Belgio 60
AU - Australia 53
AR - Argentina 50
ES - Italia 45
EU - Europa 45
PK - Pakistan 40
IQ - Iraq 36
IR - Iran 36
EC - Ecuador 30
EG - Egitto 30
ID - Indonesia 22
LT - Lituania 21
CO - Colombia 18
RO - Romania 18
AT - Austria 17
AE - Emirati Arabi Uniti 16
JM - Giamaica 16
MY - Malesia 16
HR - Croazia 15
SA - Arabia Saudita 14
VE - Venezuela 14
CH - Svizzera 13
MA - Marocco 13
PE - Perù 13
UY - Uruguay 12
PH - Filippine 11
CR - Costa Rica 10
DZ - Algeria 10
IL - Israele 10
PT - Portogallo 10
RS - Serbia 10
GR - Grecia 9
KE - Kenya 9
NI - Nicaragua 9
NP - Nepal 9
TW - Taiwan 9
CL - Cile 8
HN - Honduras 8
UZ - Uzbekistan 8
AL - Albania 7
JO - Giordania 7
AZ - Azerbaigian 6
DO - Repubblica Dominicana 6
EE - Estonia 6
KH - Cambogia 6
PA - Panama 6
PY - Paraguay 6
TH - Thailandia 6
BG - Bulgaria 5
BY - Bielorussia 5
GT - Guatemala 5
KG - Kirghizistan 5
PS - Palestinian Territory 5
TN - Tunisia 5
TT - Trinidad e Tobago 5
HU - Ungheria 4
LV - Lettonia 4
SN - Senegal 4
GA - Gabon 3
IS - Islanda 3
KZ - Kazakistan 3
LB - Libano 3
NG - Nigeria 3
OM - Oman 3
QA - Qatar 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AD - Andorra 2
AM - Armenia 2
BS - Bahamas 2
DK - Danimarca 2
GE - Georgia 2
GH - Ghana 2
LA - Repubblica Popolare Democratica del Laos 2
MK - Macedonia 2
Totale 35.549
Città #
Ashburn 1.707
Dallas 1.368
Woodbridge 1.178
Jacksonville 1.141
Singapore 1.123
Fairfield 1.048
San Jose 993
Chandler 879
Ann Arbor 683
Houston 667
Council Bluffs 624
Wilmington 610
Hong Kong 534
Beijing 495
Boardman 487
Seattle 446
Nanjing 380
Los Angeles 328
Cambridge 321
Toronto 304
New York 297
Camerino 273
Dearborn 242
Warsaw 238
The Dalles 231
Ho Chi Minh City 202
Helsinki 192
Düsseldorf 186
San Mateo 178
Seoul 171
Johannesburg 169
Tongling 165
Princeton 164
Santa Clara 159
Lawrence 157
Lauterbourg 150
Columbus 147
Istanbul 141
Nanchang 141
Kraków 138
Moscow 134
Munich 134
Buffalo 132
Dublin 131
Hanoi 128
Ogden 119
Orem 114
London 108
Shanghai 102
Milan 99
Kunming 98
São Paulo 95
Lachine 92
Shenyang 87
Phoenix 86
Chicago 73
Guangzhou 69
Jiaxing 66
Tokyo 65
Brno 63
Tianjin 63
Rome 61
Turku 61
Washington 59
Brussels 57
Chennai 55
Jinan 55
Hebei 54
Frankfurt am Main 53
San Diego 52
Brooklyn 51
Venezia 51
Changsha 48
Hangzhou 48
Montreal 45
Philadelphia 45
Manchester 42
Trieste 41
Poplar 40
Stockholm 39
Atlanta 38
Denver 38
St Louis 38
Redwood City 37
Zhengzhou 37
Mexico City 35
Wuhan 34
Ascoli Piceno 32
Boston 32
Nürnberg 31
Da Nang 30
Bremen 29
Amsterdam 28
Falls Church 28
Venice 28
Hefei 26
Leawood 26
Ningbo 26
Nuremberg 25
Mumbai 24
Totale 22.694
Nome #
1,4-Dioxane nucleus as a suitable scaffold in the building of ligands interacting with NMDA and σ1 receptors 670
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 647
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 638
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 579
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 572
Roles of Wnt/β-catenin signalling pathway in the bony repair of injured growth plate cartilage in young rats 474
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 349
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 340
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor 340
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 337
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring 320
Hyperphagic effect of novel compounds with high affinity for imidazoline I2 binding sites 317
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 309
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 302
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 292
Nano-medicine improving the bioavailability of small molecules for the prevention of neurodegenerative diseases 288
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 280
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 280
Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity 275
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane 270
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 261
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 258
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 257
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 254
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 250
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 250
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 248
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 246
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 243
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 240
Antimuscarinic activity in a series of 2-substituted 1,3-dioxolanes 240
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 237
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites 236
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 234
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 233
Discovery of Highly Selective Imidazoline Receptor Ligands 232
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 230
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 229
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 226
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 226
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 226
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 225
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 225
Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders 223
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 220
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 220
Search for selective antagonists at alpha1-adrenoreceptors: neutral or negative antagonism? 220
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 218
Dopamine D-5 receptors: A challenge to medicinal chemists 218
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 217
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 217
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 216
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 216
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 216
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 215
Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells 212
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 211
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 211
Structure-activity relationships among benextramine-related tetraamine disulfides at peripheral alpha-adrenoreceptors 209
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 208
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 208
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 208
4WD to Travel Inside the 5-HT1A Receptor World 208
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 205
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 205
Synthesis and cytotoxic activity evaluation of new Cu(I) complexes of bis(pyrazol-1-yl) acetate ligands functionalized with an NMDA receptor antagonist 205
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 203
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 203
Chain-lengthened and imidazoline analogues of nicotine 202
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 202
Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1‑[3- (4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77- LH-28-1) 201
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 200
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca2+-activated K+ permeability of erythrocytes 199
Muscarinic Thioligands with Cyclopentane Nucleus 199
Rational design and biological evaluation of novel conjugated heteroscorpionate ligands and related Copper(I/II) complexes 199
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 197
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 196
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 196
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 196
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 196
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 196
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 195
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 195
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 194
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 193
Structure-activity relationships in prazosin-related compounds. Effect of replacing a piperazine ring with an alkanediamine moiety on alpha1- adrenoreceptorblocking activity. 192
Synthesis and Structure-Activity Relationship Studies in a Series of 2-Substituted 1,3-Dioxolanes Modified at the Cationic Head. 192
Assessing the role of ghrelin and the enzyme ghrelin O-acyltransferase (GOAT) system in food reward, food motivation, and binge eating behavior 191
Novel highly potent and selective sigma1 receptor antagonists effectively block the binge eating episode in female rats 190
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 189
Rational design of novel I1-imidazoline receptor agonists 188
GluN2B-Selective N-Methyl-d-aspartate (NMDA) Receptor Antagonists Derived from 3-Benzazepines: Synthesis and Pharmacological Evaluation of Benzo[7]annulen-7-amines 186
Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors 186
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 184
Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor 183
Rational design of new alpha(2)-adrenoreceptor agonists 182
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 181
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 181
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 181
Advances in drug design and therapeutic potential of selective or multitarget 5‐HT1A receptor ligands 180
Totale 24.839
Categoria #
all - tutte 138.215
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 138.215


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.158 0 0 0 117 134 88 47 119 134 198 119 202
2022/20232.361 284 70 117 328 268 315 17 137 429 130 170 96
2023/20241.698 221 100 128 57 70 151 74 48 183 68 42 556
2024/20255.664 259 125 462 263 174 323 653 1.338 439 363 380 885
2025/20269.860 547 612 1.678 1.299 972 675 1.344 634 570 639 539 351
2026/20272.803 740 289 783 991 0 0 0 0 0 0 0 0
Totale 36.025