QUAGLIA, Wilma
 Distribuzione geografica
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Continente #
NA - Nord America 10.768
EU - Europa 4.479
AS - Asia 2.075
Continente sconosciuto - Info sul continente non disponibili 47
SA - Sud America 26
AF - Africa 14
OC - Oceania 10
Totale 17.419
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Nazione #
US - Stati Uniti d'America 10.402
CN - Cina 1.861
DE - Germania 1.146
IT - Italia 1.048
UA - Ucraina 459
SE - Svezia 425
CA - Canada 364
PL - Polonia 318
GB - Regno Unito 304
FI - Finlandia 260
FR - Francia 177
IE - Irlanda 115
CZ - Repubblica Ceca 76
SG - Singapore 69
BE - Belgio 51
EU - Europa 45
IR - Iran 26
NL - Olanda 26
IN - India 25
TR - Turchia 23
VN - Vietnam 23
RU - Federazione Russa 21
RO - Romania 15
EG - Egitto 11
AU - Australia 10
JP - Giappone 8
KR - Corea 8
PE - Perù 8
PK - Pakistan 7
BR - Brasile 6
RS - Serbia 6
GR - Grecia 5
HK - Hong Kong 5
PT - Portogallo 5
CL - Cile 4
KH - Cambogia 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
ES - Italia 3
IL - Israele 3
LT - Lituania 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BG - Bulgaria 2
BY - Bielorussia 2
CO - Colombia 2
DK - Danimarca 2
DZ - Algeria 2
HU - Ungheria 2
IS - Islanda 2
MY - Malesia 2
PS - Palestinian Territory 2
TH - Thailandia 2
VE - Venezuela 2
AR - Argentina 1
AT - Austria 1
EE - Estonia 1
IQ - Iraq 1
MN - Mongolia 1
MX - Messico 1
NO - Norvegia 1
PA - Panama 1
QA - Qatar 1
SA - Arabia Saudita 1
ZA - Sudafrica 1
Totale 17.419
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Città #
Woodbridge 1.178
Jacksonville 1.136
Fairfield 1.048
Chandler 879
Ann Arbor 682
Houston 643
Ashburn 613
Wilmington 603
Seattle 432
Nanjing 380
Cambridge 320
Toronto 270
Dearborn 242
Camerino 215
San Mateo 178
Düsseldorf 177
Warsaw 176
Beijing 171
Lawrence 157
Princeton 157
Boardman 140
Nanchang 140
Kraków 138
Helsinki 129
Columbus 126
Ogden 119
Dublin 115
Kunming 98
Lachine 92
Shanghai 91
Shenyang 85
London 81
Jiaxing 64
Guangzhou 61
Tianjin 61
Brno 58
Hebei 54
Jinan 54
New York 54
Venezia 51
Brussels 49
San Diego 48
Changsha 46
Milan 41
Hangzhou 39
Los Angeles 39
Philadelphia 39
Singapore 39
Redwood City 37
Nürnberg 31
Wuhan 31
Zhengzhou 31
Bremen 29
Falls Church 27
Washington 27
Leawood 26
Ningbo 26
Hefei 25
Venice 25
Taizhou 24
Orange 21
Verona 21
Monmouth Junction 19
Old Bridge 19
Centro 18
Dong Ket 17
Kocaeli 17
Olomouc 17
Perugia 17
Fuzhou 16
Munich 15
Dronten 14
Lanzhou 14
Strasbourg 14
Ardabil 13
Augusta 13
Yiwu 13
Auburn Hills 12
Buffalo 12
Tulsa 12
Buti 11
Changchun 11
Hanover 11
Horia 11
Indiana 11
Pesaro 11
Tappahannock 11
Jinhua 10
Baotou 9
Norwalk 9
Berlin 8
Lima 8
Mountain View 8
Rome 8
Shenzhen 8
West Jordan 8
Wuxi 8
Ascoli Piceno 7
Heze 7
Jesi 7
Totale 12.643
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Nome #
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 251
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 248
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 242
Hyperphagic effect of novel compounds with high affinity for imidazoline I2 binding sites 232
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor 228
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring 225
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 213
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 202
Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity 201
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 201
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 190
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 186
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 183
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 181
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 176
Nano-medicine improving the bioavailability of small molecules for the prevention of neurodegenerative diseases 172
1,4-Dioxane nucleus as a suitable scaffold in the building of ligands interacting with NMDA and σ1 receptors 170
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 169
Discovery of Highly Selective Imidazoline Receptor Ligands 165
null 162
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 160
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 159
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 157
Structure-activity relationships among benextramine-related tetraamine disulfides at peripheral alpha-adrenoreceptors 155
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 153
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 152
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane 152
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 151
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites 150
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 148
Roles of Wnt/β-catenin signalling pathway in the bony repair of injured growth plate cartilage in young rats 147
Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1‑[3- (4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77- LH-28-1) 144
Dopamine D-5 receptors: A challenge to medicinal chemists 144
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 143
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 143
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 141
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 141
Synthesis and cytotoxic activity evaluation of new Cu(I) complexes of bis(pyrazol-1-yl) acetate ligands functionalized with an NMDA receptor antagonist 141
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 140
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 139
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 138
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 138
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 137
Muscarinic Thioligands with Cyclopentane Nucleus 137
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca2+-activated K+ permeability of erythrocytes 136
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 135
Chain-lengthened and imidazoline analogues of nicotine 135
Structure-activity relationships in prazosin-related compounds. Effect of replacing a piperazine ring with an alkanediamine moiety on alpha1- adrenoreceptorblocking activity. 135
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 135
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 134
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 131
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 131
Structure-activity relationships among benextramine-related tetraamine disulfides. Chain length effect on alpha-adrenoreceptor blocking activity1 130
Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells 129
null 129
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 128
Synthesis and Structure-Activity Relationship Studies in a Series of 2-Substituted 1,3-Dioxolanes Modified at the Cationic Head. 128
Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors 128
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 127
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 124
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 123
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 122
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 122
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 122
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 120
I1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells. 119
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 117
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 115
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 112
Rational design and biological evaluation of novel conjugated heteroscorpionate ligands and related Copper(I/II) complexes 111
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 111
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 108
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 106
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 105
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 105
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 104
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 103
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 103
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 103
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 102
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 4. Effect of aryl and alkyl Substituents at Position 3 on α-adrenoreceptor blocking activity 102
I recettori adrenergici 101
Synthesis and Muscarinic Receptors Affinity of a series of Antagonist Bivalent Ligands 101
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 101
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 100
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 100
GluN2B-Selective N-Methyl-d-aspartate (NMDA) Receptor Antagonists Derived from 3-Benzazepines: Synthesis and Pharmacological Evaluation of Benzo[7]annulen-7-amines 100
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 99
Antimuscarinic activity in a series of 2-substituted 1,3-dioxolanes 98
Rational design of novel I1-imidazoline receptor agonists 97
Molecular determinants in the binding of novel 1,4-benzodioxan-related α1D-adrenergic receptor antagonists: a computational study 97
Fluoronorepinephrines: further pharmacological evaluation in vitro and inpithed rats 95
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 93
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 93
Imidazoline nucleus as a biologically versatile scaffold 92
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 92
Byciclic dioxolanes as potential antimuscarinic agents 91
Design and synthesis of novel imidazoline derivatives potentially targeting dopamine receptors 90
Structure-Activity Relationships in 1,4-Benzodioxan-Related Compounds. 6. Role of the Dioxane Unit on Selectivity for Alpha1-Adrenoreceptor Subtypes 90
Structure-activity relationships among methoctramine-related polymethylene tetraamines. Chain-length and substituent effects on M2-muscarinic receptor blocking activity. 90
Totale 13.757
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Categoria #
all - tutte 67.193
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.193
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20203.612 459 123 362 620 192 407 358 350 211 216 87 227
2020/20212.850 149 265 221 279 185 163 367 80 233 128 515 265
2021/20221.729 135 408 28 117 134 88 47 119 134 198 119 202
2022/20232.361 284 70 117 328 268 315 17 137 429 130 170 96
2023/20241.698 221 100 128 57 70 151 74 48 183 68 42 556
2024/2025120 120 0 0 0 0 0 0 0 0 0 0 0
Totale 17.818