Due to the lack of highly selective dopamine D1 or D5 receptor ligands, only few data about activation or blocking of these receptor subtypes are available. The present review collects the available information about molecules with notable affinity for D5 receptor subtype with the purpose to help the researchers to design novel D5 selective ligands, whose discovery may enrich the knowledge about the physiological function of such a receptor, provide information about its topography, as well as lead to novel potential therapeutic tools

Dopamine D-5 receptors: A challenge to medicinal chemists

GIORGIONI, Gianfabio;PIERGENTILI, Alessandro;RUGGIERI, Sabrina;QUAGLIA, Wilma
2008-01-01

Abstract

Due to the lack of highly selective dopamine D1 or D5 receptor ligands, only few data about activation or blocking of these receptor subtypes are available. The present review collects the available information about molecules with notable affinity for D5 receptor subtype with the purpose to help the researchers to design novel D5 selective ligands, whose discovery may enrich the knowledge about the physiological function of such a receptor, provide information about its topography, as well as lead to novel potential therapeutic tools
2008
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/112538
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