PIERGENTILI, Alessandro
 Distribuzione geografica
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Continente #
NA - Nord America 12.863
EU - Europa 6.093
AS - Asia 4.479
SA - Sud America 578
AF - Africa 76
Continente sconosciuto - Info sul continente non disponibili 39
OC - Oceania 36
Totale 24.164
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Nazione #
US - Stati Uniti d'America 12.456
CN - Cina 2.161
RU - Federazione Russa 1.491
SG - Singapore 1.185
IT - Italia 1.093
DE - Germania 1.031
BR - Brasile 495
PL - Polonia 443
UA - Ucraina 390
SE - Svezia 386
HK - Hong Kong 382
CA - Canada 350
GB - Regno Unito 338
FI - Finlandia 320
FR - Francia 198
TR - Turchia 159
KR - Corea 140
VN - Vietnam 138
IE - Irlanda 99
CZ - Repubblica Ceca 86
IN - India 80
JP - Giappone 56
BE - Belgio 53
MX - Messico 42
ZA - Sudafrica 42
NL - Olanda 39
EU - Europa 37
AR - Argentina 33
AU - Australia 33
IR - Iran 26
ES - Italia 25
BD - Bangladesh 23
IQ - Iraq 21
EC - Ecuador 17
LT - Lituania 17
PK - Pakistan 14
ID - Indonesia 13
RO - Romania 13
AT - Austria 12
HR - Croazia 12
AE - Emirati Arabi Uniti 11
EG - Egitto 11
CO - Colombia 8
UZ - Uzbekistan 8
PE - Perù 7
MA - Marocco 6
PT - Portogallo 6
RS - Serbia 6
SA - Arabia Saudita 6
AZ - Azerbaigian 5
BY - Bielorussia 5
CH - Svizzera 5
GR - Grecia 5
JO - Giordania 5
PH - Filippine 5
UY - Uruguay 5
VE - Venezuela 5
AL - Albania 4
CL - Cile 4
IL - Israele 4
KE - Kenya 4
KG - Kirghizistan 4
MY - Malesia 4
PA - Panama 4
TH - Thailandia 4
BG - Bulgaria 3
DZ - Algeria 3
HU - Ungheria 3
IS - Islanda 3
KH - Cambogia 3
KZ - Kazakistan 3
NP - Nepal 3
PY - Paraguay 3
QA - Qatar 3
SN - Senegal 3
TW - Taiwan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
DK - Danimarca 2
GE - Georgia 2
HN - Honduras 2
JM - Giamaica 2
LV - Lettonia 2
NZ - Nuova Zelanda 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
AD - Andorra 1
AO - Angola 1
BO - Bolivia 1
BZ - Belize 1
CR - Costa Rica 1
CY - Cipro 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GA - Gabon 1
GH - Ghana 1
GT - Guatemala 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LC - Santa Lucia 1
Totale 24.156
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Città #
Dallas 1.307
Woodbridge 1.039
Fairfield 955
Jacksonville 955
Ashburn 910
Chandler 756
Ann Arbor 599
Houston 572
Wilmington 535
Singapore 534
Boardman 404
Seattle 389
Hong Kong 371
Beijing 354
Nanjing 333
Cambridge 308
Warsaw 303
Dearborn 233
Toronto 232
Los Angeles 219
Camerino 208
New York 162
Düsseldorf 153
San Mateo 152
Helsinki 141
Seoul 137
Tongling 135
The Dalles 132
Kraków 129
Lawrence 128
Princeton 128
Columbus 119
Istanbul 119
Nanchang 116
Munich 107
Dublin 99
Moscow 99
Ogden 97
Buffalo 93
Kunming 86
London 82
Lachine 80
Shanghai 75
Shenyang 74
Milan 72
Brno 66
Guangzhou 57
Jiaxing 57
Turku 54
Tianjin 53
Brussels 51
Jinan 50
Chicago 47
São Paulo 47
Ho Chi Minh City 45
Venezia 45
Hebei 44
Tokyo 41
Changsha 39
Santa Clara 39
San Diego 36
Hangzhou 35
Philadelphia 34
Redwood City 34
Hanoi 31
Zhengzhou 31
Denver 29
Johannesburg 28
Washington 28
Wuhan 28
Falls Church 27
Frankfurt am Main 27
Hefei 27
Stockholm 27
Brooklyn 26
Poplar 26
Leawood 25
Phoenix 24
Venice 24
Taizhou 22
Boston 21
Centro 21
Chennai 21
Montreal 21
Ningbo 21
Nuremberg 21
Council Bluffs 20
Orem 19
Bremen 18
Nürnberg 18
Rome 18
Ankara 17
Monmouth Junction 17
Olomouc 17
Redondo Beach 17
Dong Ket 16
Fuzhou 16
Orange 16
Perugia 16
Verona 16
Totale 15.902
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Nome #
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 587
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 582
1,4-Dioxane nucleus as a suitable scaffold in the building of ligands interacting with NMDA and σ1 receptors 524
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 518
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 517
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 308
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor 305
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 304
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring 284
TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation 283
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 274
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 262
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 244
Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity 240
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 240
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 240
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 238
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 232
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane 230
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 228
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 224
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 220
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 219
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 217
Discovery of Highly Selective Imidazoline Receptor Ligands 211
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites 209
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 208
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 206
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 206
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 193
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 192
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 191
Dopamine D-5 receptors: A challenge to medicinal chemists 191
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 190
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 190
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 189
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 187
Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells 187
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 186
Design, Synthesis and Biological Evaluation of Novel Chemical Entities as Potential Anticancer Drugs and for the Control of the Metastatic Process 185
Topical antiinflammatory activity of complexes of escin and sterols with phospholipids. Part I. 183
Roles of Wnt/β-catenin signalling pathway in the bony repair of injured growth plate cartilage in young rats 183
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 183
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 183
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 183
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 182
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 182
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 182
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 181
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 179
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 177
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 176
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 176
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 174
Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1‑[3- (4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77- LH-28-1) 172
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 171
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 170
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 170
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 170
Synthesis and Structure-Activity Relationship Studies in a Series of 2-Substituted 1,3-Dioxolanes Modified at the Cationic Head. 170
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 170
4WD to Travel Inside the 5-HT1A Receptor World 169
Muscarinic Thioligands with Cyclopentane Nucleus 168
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 167
Synthesis and dopamine receptor affinities of 2-(4-fluoro-3-hydroxyphenyl)ethylamine and N-substituted derivatives 167
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 166
Chain-lengthened and imidazoline analogues of nicotine 165
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 165
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 164
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 164
Structurally diverse MDM2–p53 antagonists act as modulators of MDR-1 function in neuroblastoma 164
Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: Potent, non-peptidic blockers of the apamin-sensitive Ca2+-activated K+ channel 162
Evaluation of an Agonist Index: Affinity Ratio for Compounds Active on Muscarinic Cholinergic M2 Receptors 160
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 160
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SKCa) 159
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 158
Novel highly potent and selective sigma1 receptor antagonists effectively block the binge eating episode in female rats 158
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 158
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 157
Inhibition of WNT-β-catenin signalling promotes cartilage repair at injured growth plate in young rats 156
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 156
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 155
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 155
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 154
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 153
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 153
Agonists and antagonists targeting the different alpha(2)-adrenoceptor subtypes 152
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 152
Rational design of novel I1-imidazoline receptor agonists 150
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 150
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 148
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 146
Byciclic dioxolanes as potential antimuscarinic agents 143
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 142
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 4. Effect of aryl and alkyl Substituents at Position 3 on α-adrenoreceptor blocking activity 141
Synthesis and Muscarinic Receptors Affinity of a series of Antagonist Bivalent Ligands 140
Rational design of new alpha(2)-adrenoreceptor agonists 140
Imidazoline nucleus as a biologically versatile scaffold 139
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 136
Synthesis and muscarinic activity of some muscarone analogs 135
Totale 20.385
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Categoria #
all - tutte 93.863
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 93.863
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.525 0 0 0 0 0 150 302 68 205 123 448 229
2021/20221.426 127 330 20 89 109 80 42 98 109 169 87 166
2022/20232.041 240 68 96 297 214 257 14 132 376 121 146 80
2023/20241.432 190 86 95 43 54 132 61 46 144 56 40 485
2024/20254.631 196 100 379 207 127 241 561 1.098 370 292 313 747
2025/20264.477 436 523 1.574 1.056 769 119 0 0 0 0 0 0
Totale 24.523