PIERGENTILI, Alessandro
 Distribuzione geografica
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Continente #
NA - Nord America 14.526
EU - Europa 6.510
AS - Asia 5.705
SA - Sud America 630
AF - Africa 222
OC - Oceania 50
Continente sconosciuto - Info sul continente non disponibili 39
Totale 27.682
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Nazione #
US - Stati Uniti d'America 14.060
CN - Cina 2.346
SG - Singapore 1.647
RU - Federazione Russa 1.485
IT - Italia 1.195
DE - Germania 1.053
BR - Brasile 528
VN - Vietnam 470
PL - Polonia 456
HK - Hong Kong 438
GB - Regno Unito 394
UA - Ucraina 394
SE - Svezia 391
CA - Canada 384
FI - Finlandia 354
FR - Francia 335
ZA - Sudafrica 165
TR - Turchia 161
KR - Corea 143
IN - India 120
IE - Irlanda 104
CZ - Repubblica Ceca 86
JP - Giappone 77
BD - Bangladesh 76
NL - Olanda 59
BE - Belgio 55
MX - Messico 54
AU - Australia 47
AR - Argentina 40
EU - Europa 37
ES - Italia 35
IQ - Iraq 34
IR - Iran 31
PK - Pakistan 28
EC - Ecuador 19
EG - Egitto 19
ID - Indonesia 16
LT - Lituania 16
HR - Croazia 14
AT - Austria 13
RO - Romania 13
AE - Emirati Arabi Uniti 12
PH - Filippine 12
SA - Arabia Saudita 12
CO - Colombia 10
UZ - Uzbekistan 10
MY - Malesia 9
VE - Venezuela 9
CH - Svizzera 8
MA - Marocco 8
RS - Serbia 8
AL - Albania 7
DZ - Algeria 7
JO - Giordania 7
KE - Kenya 7
PE - Perù 7
TW - Taiwan 7
CL - Cile 6
PT - Portogallo 6
AZ - Azerbaigian 5
BY - Bielorussia 5
GR - Grecia 5
HN - Honduras 5
IL - Israele 5
JM - Giamaica 5
PA - Panama 5
SN - Senegal 5
UY - Uruguay 5
HU - Ungheria 4
KG - Kirghizistan 4
KH - Cambogia 4
NP - Nepal 4
PY - Paraguay 4
TH - Thailandia 4
BG - Bulgaria 3
GE - Georgia 3
IS - Islanda 3
KZ - Kazakistan 3
QA - Qatar 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
A2 - ???statistics.table.value.countryCode.A2??? 2
CR - Costa Rica 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GT - Guatemala 2
LB - Libano 2
LV - Lettonia 2
NZ - Nuova Zelanda 2
OM - Oman 2
PS - Palestinian Territory 2
AD - Andorra 1
AO - Angola 1
BH - Bahrain 1
BO - Bolivia 1
BS - Bahamas 1
BZ - Belize 1
CG - Congo 1
CY - Cipro 1
Totale 27.664
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Città #
Dallas 1.324
Ashburn 1.110
Woodbridge 1.039
Jacksonville 956
Fairfield 955
Singapore 905
Chandler 756
San Jose 610
Ann Arbor 600
Houston 575
Wilmington 535
Hong Kong 425
Boardman 404
Beijing 402
Seattle 392
Nanjing 333
Warsaw 315
Cambridge 308
Los Angeles 249
Toronto 239
Dearborn 233
Camerino 208
New York 197
Helsinki 174
Council Bluffs 173
Ho Chi Minh City 169
The Dalles 168
Düsseldorf 153
San Mateo 152
Johannesburg 149
Seoul 138
Tongling 134
Kraków 129
Lawrence 128
Princeton 128
Lauterbourg 121
Columbus 120
Istanbul 119
Nanchang 116
Munich 107
Dublin 104
Hanoi 103
Orem 102
Moscow 100
Buffalo 97
Ogden 97
Kunming 86
London 86
Santa Clara 83
Lachine 80
Shanghai 76
Milan 75
Shenyang 74
Brno 66
Guangzhou 57
Jiaxing 57
Tokyo 56
Turku 54
São Paulo 53
Tianjin 53
Brussels 52
Chicago 50
Jinan 50
Venezia 45
Hebei 44
Chennai 42
Frankfurt am Main 42
Changsha 39
Hangzhou 38
San Diego 36
Philadelphia 35
Denver 34
Redwood City 34
Manchester 33
Poplar 33
Zhengzhou 33
Montreal 32
Stockholm 32
Brooklyn 31
Washington 30
Wuhan 30
Phoenix 28
Falls Church 27
Hefei 27
Rome 27
Boston 26
St Louis 26
Leawood 25
Da Nang 24
Nuremberg 24
Trieste 24
Venice 24
Amsterdam 22
Ascoli Piceno 22
Mexico City 22
Taizhou 22
Centro 21
Ningbo 21
Sydney 21
Mumbai 20
Totale 18.255
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Nome #
1,4-Dioxane nucleus as a suitable scaffold in the building of ligands interacting with NMDA and σ1 receptors 645
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 623
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 622
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 560
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 555
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 339
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 332
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor 327
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 323
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring 304
TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation 302
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 299
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 290
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 268
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 268
Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity 263
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 262
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 259
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane 254
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 250
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 247
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 241
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 241
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 237
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 236
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 227
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites 226
Discovery of Highly Selective Imidazoline Receptor Ligands 224
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 219
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 218
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 218
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 218
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 218
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 217
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 216
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 212
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 211
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 209
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 209
Dopamine D-5 receptors: A challenge to medicinal chemists 209
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 208
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 207
Roles of Wnt/β-catenin signalling pathway in the bony repair of injured growth plate cartilage in young rats 207
Design, Synthesis and Biological Evaluation of Novel Chemical Entities as Potential Anticancer Drugs and for the Control of the Metastatic Process 206
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 206
Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells 205
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 204
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 202
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 201
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 200
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 198
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 197
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 197
4WD to Travel Inside the 5-HT1A Receptor World 197
Inhibition of WNT-β-catenin signalling promotes cartilage repair at injured growth plate in young rats 196
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 195
Topical antiinflammatory activity of complexes of escin and sterols with phospholipids. Part I. 195
Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1‑[3- (4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77- LH-28-1) 193
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 193
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 192
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 191
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 190
Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders 189
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 189
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 188
Chain-lengthened and imidazoline analogues of nicotine 187
Muscarinic Thioligands with Cyclopentane Nucleus 187
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 186
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 186
Synthesis and dopamine receptor affinities of 2-(4-fluoro-3-hydroxyphenyl)ethylamine and N-substituted derivatives 184
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 184
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 183
Synthesis and Structure-Activity Relationship Studies in a Series of 2-Substituted 1,3-Dioxolanes Modified at the Cationic Head. 181
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 181
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 180
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 180
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 179
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 178
Structurally diverse MDM2–p53 antagonists act as modulators of MDR-1 function in neuroblastoma 178
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 178
Novel highly potent and selective sigma1 receptor antagonists effectively block the binge eating episode in female rats 177
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 176
Agonists and antagonists targeting the different alpha(2)-adrenoceptor subtypes 175
Evaluation of an Agonist Index: Affinity Ratio for Compounds Active on Muscarinic Cholinergic M2 Receptors 175
Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: Potent, non-peptidic blockers of the apamin-sensitive Ca2+-activated K+ channel 175
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SKCa) 174
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 173
Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor 173
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 172
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 171
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 171
Rational design of novel I1-imidazoline receptor agonists 170
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 169
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 169
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 168
Assessing the role of ghrelin and the enzyme ghrelin O-acyltransferase (GOAT) system in food reward, food motivation, and binge eating behavior 167
Advances in drug design and therapeutic potential of selective or multitarget 5‐HT1A receptor ligands 166
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 164
Imidazoline nucleus as a biologically versatile scaffold 162
Byciclic dioxolanes as potential antimuscarinic agents 161
Totale 22.884
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Categoria #
all - tutte 104.672
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 104.672
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021229 0 0 0 0 0 0 0 0 0 0 0 229
2021/20221.426 127 330 20 89 109 80 42 98 109 169 87 166
2022/20232.041 240 68 96 297 214 257 14 132 376 121 146 80
2023/20241.438 190 86 95 43 54 132 61 46 146 56 41 488
2024/20254.611 197 100 378 207 127 240 559 1.094 369 292 313 735
2025/20268.017 436 523 1.587 1.048 773 567 1.054 479 445 533 431 141
Totale 28.049