GIANNELLA, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 7.889
EU - Europa 3.225
AS - Asia 1.765
Continente sconosciuto - Info sul continente non disponibili 36
SA - Sud America 12
OC - Oceania 9
AF - Africa 3
Totale 12.939
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Nazione #
US - Stati Uniti d'America 7.620
CN - Cina 1.379
DE - Germania 791
IT - Italia 719
UA - Ucraina 332
SE - Svezia 302
CA - Canada 266
PL - Polonia 247
GB - Regno Unito 227
FI - Finlandia 223
SG - Singapore 196
FR - Francia 142
TR - Turchia 98
IE - Irlanda 77
CZ - Repubblica Ceca 62
BE - Belgio 36
EU - Europa 35
IN - India 18
VN - Vietnam 18
IR - Iran 16
NL - Olanda 15
RU - Federazione Russa 14
RO - Romania 11
AU - Australia 9
JP - Giappone 8
BR - Brasile 5
RS - Serbia 5
GR - Grecia 4
HK - Hong Kong 4
ID - Indonesia 4
KR - Corea 4
CL - Cile 3
KH - Cambogia 3
LT - Lituania 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BY - Bielorussia 2
CH - Svizzera 2
ES - Italia 2
GE - Georgia 2
HU - Ungheria 2
IL - Israele 2
TH - Thailandia 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
AT - Austria 1
BO - Bolivia 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
IQ - Iraq 1
JM - Giamaica 1
KG - Kirghizistan 1
LV - Lettonia 1
MA - Marocco 1
MN - Mongolia 1
MX - Messico 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
SA - Arabia Saudita 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 12.939
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Città #
Jacksonville 836
Woodbridge 820
Chandler 671
Fairfield 652
Ann Arbor 534
Wilmington 431
Ashburn 409
Houston 402
Boardman 326
Nanjing 281
Seattle 261
Toronto 196
Cambridge 195
Dearborn 191
Beijing 138
Düsseldorf 134
San Mateo 133
Singapore 132
Warsaw 126
Kraków 121
Helsinki 115
Lawrence 106
Princeton 106
Nanchang 97
Columbus 95
Camerino 92
Istanbul 83
Dublin 77
Ogden 77
Kunming 68
Lachine 67
Shanghai 64
Shenyang 64
London 53
Tianjin 49
Los Angeles 48
Brno 47
Jiaxing 45
Guangzhou 44
Hebei 44
Venezia 44
Changsha 37
New York 37
Brussels 36
Jinan 34
Milan 31
San Diego 30
Hangzhou 29
Munich 29
Redwood City 29
Philadelphia 26
Wuhan 25
Falls Church 24
Venice 24
Washington 23
Zhengzhou 23
Hefei 20
Taizhou 20
Leawood 19
Ningbo 17
Nürnberg 17
Orange 17
Monmouth Junction 16
Chicago 15
Fuzhou 15
Old Bridge 14
Olomouc 14
Verona 14
Auburn Hills 13
Centro 13
Changchun 13
Bremen 12
Dong Ket 12
Kocaeli 12
Perugia 12
Buffalo 10
Lanzhou 10
Yiwu 10
Augusta 9
Espoo 9
Pesaro 9
Ardabil 8
Baotou 8
Enterprise 8
Hanover 8
Mountain View 8
Tappahannock 8
Tulsa 8
Berlin 7
Heze 7
Horia 7
Indiana 7
Jinhua 7
Nantong 7
New Delhi 7
Norwalk 7
Buti 6
Detroit 6
Dronten 6
Nuremberg 6
Totale 9.389
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Nome #
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 267
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 265
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 248
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 233
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 208
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 208
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 198
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 193
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 192
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 187
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 185
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 173
Discovery of Highly Selective Imidazoline Receptor Ligands 169
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 168
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 164
Biological profile and bioavailability of imidazoline compounds on morphine tolerance modulation 164
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 164
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 160
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 160
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 156
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 155
The Camerino symposium series (1978-2013): a privileged observatory of receptorology development 151
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 149
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 148
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 147
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 145
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 144
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 144
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 144
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 144
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 141
Muscarinic Thioligands with Cyclopentane Nucleus 141
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 140
Chain-lengthened and imidazoline analogues of nicotine 140
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 139
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 139
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 137
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 135
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 135
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 133
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 133
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 129
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 128
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 127
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 127
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 125
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 121
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 119
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 117
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 117
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 115
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 114
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 113
Synthesis and muscarinic activity of some muscarone analogs 110
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 110
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 110
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 109
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 109
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 108
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 107
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 107
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 107
I recettori adrenergici 106
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 106
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 4. Effect of aryl and alkyl Substituents at Position 3 on α-adrenoreceptor blocking activity 106
BIOLOGICAL PROFILE AND BIOAVAILABILITY OF IMIDAZOLINE COMPOUNDS AFFECT THEIR MODULATORY ACTIVITY ON MORPHINE TOLERANCE 105
Age-related Changes in the Density of Muscarinic Cholinergic M1 and M2 Receptor Subtypes in Pyramidal Neurons or the rat Hippocampus 104
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 103
Rational design of novel I1-imidazoline receptor agonists 102
Molecular determinants in the binding of novel 1,4-benzodioxan-related α1D-adrenergic receptor antagonists: a computational study 102
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 102
Imidazoline nucleus as a biologically versatile scaffold 99
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 99
Agonists and antagonists targeting the different alpha(2)-adrenoceptor subtypes 98
Structure-Activity Relationships in 1,4-Benzodioxan-Related Compounds. 6. Role of the Dioxane Unit on Selectivity for Alpha1-Adrenoreceptor Subtypes 96
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 96
Design and synthesis of novel imidazoline derivatives potentially targeting dopamine receptors 95
Byciclic dioxolanes as potential antimuscarinic agents 95
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 95
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 95
Hybrid molecules from xanomeline and 77-LH-28-1 as potential novel M1 muscarinic agonists 94
Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel alpha1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and alpha1d computational study 94
Copresence of 1,4-dioxane and quinuclidine nuclei in the design of novel muscarinic antagonists 93
Rational design of new alpha(2)-adrenoreceptor agonists 93
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 93
Aminopyrimidines as inhibitors of the Wnt signalling pathway 91
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 90
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 90
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 89
Enantiomers of 6,6-diphenyl-1,4-dioxane derivatives to highlight stereochemical requirements for selective alpha1D-AR and 5- HT1A receptor recognition 89
NOVEL IMIDAZOLINE MOLECULES INSPIRED BY THE PHARMACOLOGICAL PROFILE OF AGMATINE AS POTENTIAL TOOLS IN MANAGING OPIOID ADDICTION 88
4WD to Travel Inside the 5-HT1A Receptor World 88
Might the observed alpha2A-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? 87
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 5. Effects of Modification of the side chain on alpha-adrenoreceptor blocking Activity 86
Binding of Tracizolines to the Imidazoline Receptor. Role of Lipophilicity in Quantitative Structure-Activity Relationship Models. 86
Coupling of I-1 Imidazoline Receptors to the cAMP Pathway: Studies with a Highly Selective Ligand, Benazoline 82
Alpha2C-adrenoceptor modulators: a patent review 80
Novel α1-adrenoreceptor antagonists related to openphendioxan: biological evaluation and α1d computational study 79
Synergic stimulation of serotonin 5-HT1A receptor and α2-adrenoceptors for neuropathic pain relief: Preclinical effects of 2-substituted imidazoline derivatives 77
Novel muscarinic antagonists designed on the 1,4-dioxane scaffold 76
Totale 12.824
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Categoria #
all - tutte 51.142
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.142
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.464 0 0 0 0 139 302 261 253 135 151 55 168
2020/20211.829 96 159 96 189 120 118 207 32 165 86 367 194
2021/20221.135 94 281 14 78 83 61 29 77 86 125 76 131
2022/20231.704 200 67 71 269 183 227 10 105 313 97 108 54
2023/20241.105 167 63 74 33 46 97 45 17 113 40 25 385
2024/2025734 142 80 283 168 61 0 0 0 0 0 0 0
Totale 13.185