GIANNELLA, Mario
 Distribuzione geografica
Continente #
NA - Nord America 10.201
EU - Europa 4.775
AS - Asia 3.507
SA - Sud America 421
AF - Africa 50
Continente sconosciuto - Info sul continente non disponibili 36
OC - Oceania 33
Totale 19.023
Nazione #
US - Stati Uniti d'America 9.852
CN - Cina 1.797
RU - Federazione Russa 1.159
SG - Singapore 902
DE - Germania 883
IT - Italia 769
BR - Brasile 364
UA - Ucraina 338
SE - Svezia 318
CA - Canada 305
GB - Regno Unito 285
FI - Finlandia 273
PL - Polonia 273
HK - Hong Kong 260
FR - Francia 169
TR - Turchia 135
KR - Corea 114
VN - Vietnam 89
IE - Irlanda 79
CZ - Repubblica Ceca 63
IN - India 60
BE - Belgio 41
EU - Europa 35
JP - Giappone 35
AU - Australia 31
MX - Messico 31
NL - Olanda 25
ZA - Sudafrica 25
AR - Argentina 21
ES - Italia 21
IR - Iran 20
BD - Bangladesh 19
LT - Lituania 15
EC - Ecuador 14
HR - Croazia 12
IQ - Iraq 12
RO - Romania 12
EG - Egitto 11
ID - Indonesia 9
AE - Emirati Arabi Uniti 7
AT - Austria 7
MA - Marocco 6
RS - Serbia 6
PE - Perù 5
SA - Arabia Saudita 5
AL - Albania 4
AZ - Azerbaigian 4
CH - Svizzera 4
CO - Colombia 4
GR - Grecia 4
JO - Giordania 4
VE - Venezuela 4
BY - Bielorussia 3
CL - Cile 3
DZ - Algeria 3
HU - Ungheria 3
IL - Israele 3
KE - Kenya 3
KG - Kirghizistan 3
KH - Cambogia 3
NP - Nepal 3
PA - Panama 3
PH - Filippine 3
PY - Paraguay 3
TH - Thailandia 3
BG - Bulgaria 2
BO - Bolivia 2
GE - Georgia 2
HN - Honduras 2
JM - Giamaica 2
LV - Lettonia 2
NZ - Nuova Zelanda 2
PK - Pakistan 2
QA - Qatar 2
TW - Taiwan 2
UZ - Uzbekistan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AD - Andorra 1
BZ - Belize 1
CR - Costa Rica 1
CY - Cipro 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GH - Ghana 1
GT - Guatemala 1
IS - Islanda 1
KZ - Kazakistan 1
LB - Libano 1
LC - Santa Lucia 1
LK - Sri Lanka 1
MN - Mongolia 1
MU - Mauritius 1
MY - Malesia 1
PS - Palestinian Territory 1
PT - Portogallo 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 19.023
Città #
Dallas 982
Jacksonville 836
Woodbridge 820
Ashburn 673
Chandler 671
Fairfield 652
Ann Arbor 534
Wilmington 432
Houston 410
Singapore 403
Boardman 326
Beijing 293
Nanjing 281
Seattle 266
Hong Kong 256
Toronto 204
Cambridge 196
Dearborn 191
Los Angeles 168
Warsaw 149
Düsseldorf 140
San Mateo 133
New York 127
The Dalles 124
Kraków 121
Helsinki 119
Seoul 109
Columbus 107
Lawrence 107
Tongling 107
Princeton 106
Camerino 100
Istanbul 99
Nanchang 97
Munich 89
Buffalo 79
Dublin 79
Moscow 77
Ogden 77
Kunming 68
Shanghai 68
Lachine 67
Shenyang 66
London 63
Tianjin 50
Brno 47
Guangzhou 46
Jiaxing 46
Turku 45
Hebei 44
Venezia 44
Milan 42
Brussels 41
São Paulo 41
Changsha 39
Chicago 37
Jinan 34
Santa Clara 34
Hangzhou 31
San Diego 31
Redwood City 29
Denver 27
Ho Chi Minh City 27
Philadelphia 27
Washington 26
Zhengzhou 26
Tokyo 25
Wuhan 25
Falls Church 24
Venice 24
Poplar 22
Hefei 21
Hanoi 20
Taizhou 20
Boston 19
Leawood 19
Brooklyn 18
Chennai 18
Montreal 18
Stockholm 18
Ningbo 17
Nürnberg 17
Orange 17
Monmouth Junction 16
Phoenix 16
Redondo Beach 16
Ankara 15
Council Bluffs 15
Frankfurt am Main 15
Fuzhou 15
Johannesburg 15
Olomouc 15
Orem 15
Old Bridge 14
Verona 14
Auburn Hills 13
Augusta 13
Centro 13
Changchun 13
Melbourne 13
Totale 12.474
Nome #
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 587
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 582
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 518
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 517
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 308
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 304
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 274
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 262
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 244
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 240
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 240
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 232
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 228
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 224
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 220
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 219
Biological profile and bioavailability of imidazoline compounds on morphine tolerance modulation 218
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 217
Discovery of Highly Selective Imidazoline Receptor Ligands 211
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 208
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 206
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 206
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 200
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 193
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 192
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 191
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 190
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 190
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 189
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 189
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 187
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 186
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 183
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 183
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 183
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 182
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 182
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 182
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 181
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 179
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 177
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 176
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 176
The Camerino symposium series (1978-2013): a privileged observatory of receptorology development 176
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 174
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 171
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 170
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 170
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 170
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 170
4WD to Travel Inside the 5-HT1A Receptor World 169
Muscarinic Thioligands with Cyclopentane Nucleus 168
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 167
BIOLOGICAL PROFILE AND BIOAVAILABILITY OF IMIDAZOLINE COMPOUNDS AFFECT THEIR MODULATORY ACTIVITY ON MORPHINE TOLERANCE 167
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 166
Chain-lengthened and imidazoline analogues of nicotine 165
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 165
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 164
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 164
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 160
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 158
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 158
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 157
Age-related Changes in the Density of Muscarinic Cholinergic M1 and M2 Receptor Subtypes in Pyramidal Neurons or the rat Hippocampus 156
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 155
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 155
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 154
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 153
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 153
Agonists and antagonists targeting the different alpha(2)-adrenoceptor subtypes 152
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 152
Rational design of novel I1-imidazoline receptor agonists 150
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 150
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 148
I recettori adrenergici 148
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 146
Byciclic dioxolanes as potential antimuscarinic agents 143
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 142
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 4. Effect of aryl and alkyl Substituents at Position 3 on α-adrenoreceptor blocking activity 141
Rational design of new alpha(2)-adrenoreceptor agonists 140
Imidazoline nucleus as a biologically versatile scaffold 139
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 136
Synthesis and muscarinic activity of some muscarone analogs 135
Hybrid molecules from xanomeline and 77-LH-28-1 as potential novel M1 muscarinic agonists 134
Binding of Tracizolines to the Imidazoline Receptor. Role of Lipophilicity in Quantitative Structure-Activity Relationship Models. 134
NOVEL IMIDAZOLINE MOLECULES INSPIRED BY THE PHARMACOLOGICAL PROFILE OF AGMATINE AS POTENTIAL TOOLS IN MANAGING OPIOID ADDICTION 133
Design and synthesis of novel imidazoline derivatives potentially targeting dopamine receptors 128
Structure-Activity Relationships in 1,4-Benzodioxan-Related Compounds. 6. Role of the Dioxane Unit on Selectivity for Alpha1-Adrenoreceptor Subtypes 128
Molecular determinants in the binding of novel 1,4-benzodioxan-related α1D-adrenergic receptor antagonists: a computational study 127
Advances in drug design and therapeutic potential of selective or multitarget 5‐HT1A receptor ligands 124
Aminopyrimidines as inhibitors of the Wnt signalling pathway 123
Copresence of 1,4-dioxane and quinuclidine nuclei in the design of novel muscarinic antagonists 121
Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel alpha1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and alpha1d computational study 119
Enantiomers of 6,6-diphenyl-1,4-dioxane derivatives to highlight stereochemical requirements for selective alpha1D-AR and 5- HT1A receptor recognition 118
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 5. Effects of Modification of the side chain on alpha-adrenoreceptor blocking Activity 116
Might the observed alpha2A-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? 115
Novel α1-adrenoreceptor antagonists related to openphendioxan: biological evaluation and α1d computational study 106
Novel muscarinic antagonists designed on the 1,4-dioxane scaffold 104
Coupling of I-1 Imidazoline Receptors to the cAMP Pathway: Studies with a Highly Selective Ligand, Benazoline 102
Alpha2C-adrenoceptor modulators: a patent review 102
Totale 18.667
Categoria #
all - tutte 72.077
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.077


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.169 0 0 0 0 0 118 207 32 165 86 367 194
2021/20221.135 94 281 14 78 83 61 29 77 86 125 76 131
2022/20231.704 200 67 71 269 183 227 10 105 313 97 108 54
2023/20241.105 167 63 74 33 46 97 45 17 113 40 25 385
2024/20253.507 142 80 283 168 88 193 427 825 296 225 245 535
2025/20263.311 323 396 1.144 748 605 95 0 0 0 0 0 0
Totale 19.269