GIANNELLA, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 7.530
EU - Europa 3.063
AS - Asia 1.154
Continente sconosciuto - Info sul continente non disponibili 36
SA - Sud America 10
OC - Oceania 8
AF - Africa 2
Totale 11.803
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Nazione #
US - Stati Uniti d'America 7.264
CN - Cina 1.056
DE - Germania 762
IT - Italia 684
UA - Ucraina 332
SE - Svezia 302
CA - Canada 264
PL - Polonia 247
GB - Regno Unito 227
FI - Finlandia 198
FR - Francia 141
IE - Irlanda 77
EU - Europa 35
BE - Belgio 31
IN - India 18
VN - Vietnam 17
IR - Iran 16
TR - Turchia 15
NL - Olanda 14
RO - Romania 11
RU - Federazione Russa 11
AU - Australia 8
JP - Giappone 7
RS - Serbia 5
BR - Brasile 4
HK - Hong Kong 4
KR - Corea 4
CL - Cile 3
GR - Grecia 3
KH - Cambogia 3
LT - Lituania 3
SG - Singapore 3
AE - Emirati Arabi Uniti 2
BG - Bulgaria 2
BY - Bielorussia 2
CH - Svizzera 2
ES - Italia 2
HU - Ungheria 2
IL - Israele 2
TH - Thailandia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
AT - Austria 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
GE - Georgia 1
IQ - Iraq 1
MN - Mongolia 1
MX - Messico 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
SA - Arabia Saudita 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 11.803
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Città #
Jacksonville 836
Woodbridge 820
Chandler 671
Fairfield 652
Ann Arbor 534
Wilmington 431
Houston 402
Ashburn 374
Nanjing 280
Seattle 261
Toronto 196
Cambridge 195
Dearborn 191
Düsseldorf 134
San Mateo 133
Warsaw 126
Kraków 121
Beijing 106
Lawrence 106
Princeton 106
Helsinki 99
Boardman 97
Nanchang 97
Columbus 95
Camerino 89
Dublin 77
Ogden 77
Kunming 68
Lachine 67
Shenyang 62
London 53
Tianjin 49
Hebei 44
Venezia 44
Changsha 37
New York 37
Jiaxing 33
Jinan 33
Brussels 31
San Diego 30
Milan 29
Redwood City 29
Hangzhou 27
Los Angeles 27
Philadelphia 26
Falls Church 24
Venice 24
Washington 23
Zhengzhou 23
Hefei 20
Guangzhou 19
Leawood 19
Shanghai 19
Taizhou 18
Ningbo 17
Nürnberg 17
Orange 17
Monmouth Junction 16
Old Bridge 14
Verona 14
Auburn Hills 13
Centro 13
Changchun 13
Fuzhou 13
Bremen 12
Dong Ket 12
Kocaeli 12
Perugia 12
Lanzhou 10
Augusta 9
Pesaro 9
Ardabil 8
Baotou 8
Enterprise 8
Hanover 8
Mountain View 8
Tappahannock 8
Tulsa 8
Berlin 7
Buffalo 7
Horia 7
Indiana 7
New Delhi 7
Norwalk 7
Buti 6
Detroit 6
Dronten 6
Nuremberg 6
Rome 6
Strasbourg 6
West Jordan 6
Chengdu 5
Hounslow 5
Portland 5
Porto Sant'elpidio 5
Scafati 5
Xian 5
Andover 4
Ascoli Piceno 4
Campbell 4
Totale 8.626
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Nome #
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 242
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 239
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 231
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 208
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 196
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 196
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 185
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 178
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 178
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 177
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 168
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 165
Discovery of Highly Selective Imidazoline Receptor Ligands 164
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 159
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 155
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 150
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 150
Biological profile and bioavailability of imidazoline compounds on morphine tolerance modulation 150
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 147
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 144
The Camerino symposium series (1978-2013): a privileged observatory of receptorology development 143
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 141
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 140
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 139
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 138
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 138
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 137
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 137
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 135
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 134
Muscarinic Thioligands with Cyclopentane Nucleus 133
Chain-lengthened and imidazoline analogues of nicotine 131
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 131
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 130
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 130
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 127
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 127
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 125
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 124
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 122
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 120
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 119
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 119
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 118
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 118
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 117
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 112
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 109
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 107
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 105
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 104
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 101
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 100
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 100
Synthesis and muscarinic activity of some muscarone analogs 100
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 100
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 4. Effect of aryl and alkyl Substituents at Position 3 on α-adrenoreceptor blocking activity 99
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 99
I recettori adrenergici 97
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 97
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 96
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 96
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 95
Molecular determinants in the binding of novel 1,4-benzodioxan-related α1D-adrenergic receptor antagonists: a computational study 94
BIOLOGICAL PROFILE AND BIOAVAILABILITY OF IMIDAZOLINE COMPOUNDS AFFECT THEIR MODULATORY ACTIVITY ON MORPHINE TOLERANCE 94
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 93
Rational design of novel I1-imidazoline receptor agonists 92
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 92
Age-related Changes in the Density of Muscarinic Cholinergic M1 and M2 Receptor Subtypes in Pyramidal Neurons or the rat Hippocampus 92
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 90
Imidazoline nucleus as a biologically versatile scaffold 89
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 88
Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel alpha1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and alpha1d computational study 88
Design and synthesis of novel imidazoline derivatives potentially targeting dopamine receptors 87
Agonists and antagonists targeting the different alpha(2)-adrenoceptor subtypes 87
Structure-Activity Relationships in 1,4-Benzodioxan-Related Compounds. 6. Role of the Dioxane Unit on Selectivity for Alpha1-Adrenoreceptor Subtypes 87
Byciclic dioxolanes as potential antimuscarinic agents 87
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 87
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 86
Copresence of 1,4-dioxane and quinuclidine nuclei in the design of novel muscarinic antagonists 85
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 85
Hybrid molecules from xanomeline and 77-LH-28-1 as potential novel M1 muscarinic agonists 84
Rational design of new alpha(2)-adrenoreceptor agonists 84
Might the observed alpha2A-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? 82
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 82
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 82
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 81
Aminopyrimidines as inhibitors of the Wnt signalling pathway 81
NOVEL IMIDAZOLINE MOLECULES INSPIRED BY THE PHARMACOLOGICAL PROFILE OF AGMATINE AS POTENTIAL TOOLS IN MANAGING OPIOID ADDICTION 80
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 5. Effects of Modification of the side chain on alpha-adrenoreceptor blocking Activity 79
Enantiomers of 6,6-diphenyl-1,4-dioxane derivatives to highlight stereochemical requirements for selective alpha1D-AR and 5- HT1A receptor recognition 79
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 78
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 78
Binding of Tracizolines to the Imidazoline Receptor. Role of Lipophilicity in Quantitative Structure-Activity Relationship Models. 76
Coupling of I-1 Imidazoline Receptors to the cAMP Pathway: Studies with a Highly Selective Ligand, Benazoline 74
4WD to Travel Inside the 5-HT1A Receptor World 74
Alpha2C-adrenoceptor modulators: a patent review 73
Synergic stimulation of serotonin 5-HT1A receptor and α2-adrenoceptors for neuropathic pain relief: Preclinical effects of 2-substituted imidazoline derivatives 71
Novel α1-adrenoreceptor antagonists related to openphendioxan: biological evaluation and α1d computational study 70
Novel muscarinic antagonists designed on the 1,4-dioxane scaffold 67
Totale 11.750
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Categoria #
all - tutte 40.647
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.647
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019533 0 0 0 0 0 0 0 0 0 0 214 319
2019/20202.566 338 79 263 422 139 302 261 253 135 151 55 168
2020/20211.829 96 159 96 189 120 118 207 32 165 86 367 194
2021/20221.135 94 281 14 78 83 61 29 77 86 125 76 131
2022/20231.704 200 67 71 269 183 227 10 105 313 97 108 54
2023/2024701 167 63 74 33 46 97 45 17 113 40 6 0
Totale 12.047