GIANNELLA, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 7.610
EU - Europa 3.167
AS - Asia 1.590
Continente sconosciuto - Info sul continente non disponibili 36
SA - Sud America 11
OC - Oceania 9
AF - Africa 2
Totale 12.425
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Nazione #
US - Stati Uniti d'America 7.343
CN - Cina 1.367
DE - Germania 780
IT - Italia 703
UA - Ucraina 332
SE - Svezia 302
CA - Canada 264
PL - Polonia 247
GB - Regno Unito 227
FI - Finlandia 199
FR - Francia 141
SG - Singapore 128
IE - Irlanda 77
CZ - Repubblica Ceca 62
BE - Belgio 35
EU - Europa 35
IN - India 18
VN - Vietnam 17
IR - Iran 16
TR - Turchia 15
NL - Olanda 14
RU - Federazione Russa 12
RO - Romania 11
AU - Australia 9
JP - Giappone 7
BR - Brasile 5
RS - Serbia 5
HK - Hong Kong 4
KR - Corea 4
CL - Cile 3
GR - Grecia 3
KH - Cambogia 3
LT - Lituania 3
AE - Emirati Arabi Uniti 2
BG - Bulgaria 2
BY - Bielorussia 2
CH - Svizzera 2
ES - Italia 2
HU - Ungheria 2
IL - Israele 2
TH - Thailandia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
AT - Austria 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
GE - Georgia 1
IQ - Iraq 1
JM - Giamaica 1
MN - Mongolia 1
MX - Messico 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
SA - Arabia Saudita 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 12.425
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Città #
Jacksonville 836
Woodbridge 820
Chandler 671
Fairfield 652
Ann Arbor 534
Wilmington 431
Houston 402
Ashburn 388
Nanjing 281
Seattle 261
Toronto 196
Cambridge 195
Dearborn 191
Beijing 138
Düsseldorf 134
San Mateo 133
Warsaw 126
Kraków 121
Boardman 112
Lawrence 106
Princeton 106
Helsinki 100
Nanchang 97
Columbus 95
Camerino 91
Singapore 79
Dublin 77
Ogden 77
Kunming 68
Lachine 67
Shenyang 64
Shanghai 63
London 53
Tianjin 49
Brno 47
Jiaxing 45
Guangzhou 44
Hebei 44
Venezia 44
Los Angeles 41
Changsha 37
New York 37
Brussels 35
Jinan 34
San Diego 30
Hangzhou 29
Milan 29
Redwood City 29
Philadelphia 26
Wuhan 25
Falls Church 24
Venice 24
Washington 23
Zhengzhou 23
Hefei 20
Taizhou 20
Leawood 19
Munich 18
Ningbo 17
Nürnberg 17
Orange 17
Monmouth Junction 16
Chicago 15
Fuzhou 15
Old Bridge 14
Olomouc 14
Verona 14
Auburn Hills 13
Centro 13
Changchun 13
Bremen 12
Dong Ket 12
Kocaeli 12
Perugia 12
Buffalo 10
Lanzhou 10
Yiwu 10
Augusta 9
Pesaro 9
Ardabil 8
Baotou 8
Enterprise 8
Hanover 8
Mountain View 8
Tappahannock 8
Tulsa 8
Berlin 7
Heze 7
Horia 7
Indiana 7
Jinhua 7
New Delhi 7
Norwalk 7
Buti 6
Detroit 6
Dronten 6
Nuremberg 6
Rome 6
Santa Clara 6
Shenzhen 6
Totale 8.982
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Nome #
1,4-Dioxane, a Suitable Scaffold for the Development of Novel M3 Muscarinic Receptor Antagonists 256
1,4-DIOXANE NUCLEUS AS A SUITABLE SCAFFOLD FOR NOVEL D2-LIKE RECEPTOR LIGANDS 255
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor 244
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation 214
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus 203
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction 203
1'-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective sigma1 lingand 191
Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease 190
Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions 183
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 181
1,4-Dioxane ring as a promising template of novel 5-HT1A full agonists 179
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway 170
Discovery of Highly Selective Imidazoline Receptor Ligands 166
Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on alpha1-adrenoreceptor blocking activity 161
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia 159
33rd camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 157
Biological profile and bioavailability of imidazoline compounds on morphine tolerance modulation 156
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 154
2-(2-Phenylcyclopropyl)imidazolines: Reversed Enantioselective Interaction at I1 and I2 Imidazoline Receptors 154
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 152
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement. 149
The Camerino symposium series (1978-2013): a privileged observatory of receptorology development 148
Structure−Activity Relationships in 1,4-Benzodioxan-Related Compounds. 11.1 Reversed Enantioselectivity of 1,4-Dioxane Derivatives in α1‑Adrenergic and 5‑HT1A Receptor Binding Sites Recognition 145
Novel Highly Potent and Selective σ1 Receptor Antagonists Related to Spipethiane 144
Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACh) receptor binding 142
Use of frozen sections for the pharmacological characterization of compounds active on neurotransmitter receptors 142
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation 142
Imidazoline binding sites (IBS) profile modulation: Key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues 142
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors 140
alpha(2)-Adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha2C-subtype 138
Dioxane and Oxathiane Nuclei: Suitable Substructures for Muscarinic Agonists 138
Muscarinic Thioligands with Cyclopentane Nucleus 138
Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine 136
Chain-lengthened and imidazoline analogues of nicotine 136
Potent muscarinic antagonists bearing 1,4-dioxane scaffold 136
Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells 135
Synthesis and muscarinic properties of (1S*,3R*,5R*)-trimethyl(1-methyl-6-oxabicyclo[3.1.0]hex-3-yl)methyl ammonium iodide 132
Deoxamuscaroneoxime Devatives as useful Muscarinic Aginist to Explore the Muscarinic Subsite: Demox, Amodulator of Orthosteric and Allosteric Site at Cardiac Muscarinic M2 Receptors. 131
Low doses of allyphenyline and cyclomethyline, effective against morphine dependence, elicit an antidepressant-like effect 131
3-Phenyl analogues of 2-[[[2-(2,6-Dimethoxyphenoxyethyllamino]methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha1-adrenoreceptor antagonists1 128
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity 125
Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes 124
14th Camerino-Noordwijkerhout Symposium - Ongoing Progress in Receptor Chemistry 124
The 2-substituted imidazoline ring linked to an aromatic moiety by a biatomic bridge: a bioversatile scaffold 124
Novel 1,4-dioxane derivatives as NMDA receptor channel blockers 123
Synthesis, Absolute Configuration, and Biological Profile of the Enantiomers of trans-[2-(2,6-Dimethoxypheoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (Mephendioxan), a Potent Competitive alpha 1A-Adrenoreceptor Antagonist 122
Might Adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? 118
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 115
Solution-phase synthesis of ICG-001, a beta-turn peptidomimetic molecule inhibitor of beta-catenin-Tcf-mediated transcription 113
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models 111
Alpha(2)-Adrenoreceptors Profile Modulation. 3. (R)-(+)-m-Nitrobiphenyline, a New Efficient and alpha(2C)-Subtype Selective Agonist. 110
Fruitful Adrenergic alpha(2C)-Agonism/alpha(2A)-Antagonism Combination to Prevent and Contrast Morphine Tolerance and Dependence 108
33rd Camerino-Cyprus Symposium - Receptor Chemistry: Reality and Vision 107
From benzodioxane to 1,4-dioxane scaffold in the design of 5-HT1A serotoninergic full agonists from α1-adrenergic antagonists 106
alpha(2)-adrenoreceptors profile modulation. 4. From antagonist, to agonist behavior 106
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4 chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation 106
Synthesis and muscarinic activity of some muscarone analogs 105
31st Camerino-Cyprus-Noordwijkerhout Symposium - Receptor Chemistry Skyline 105
TESTING D2-LIKE RECEPTOR AFFINITY AND SELECTIVITY WITH NOVEL IMIDAZOLINE DERIVATIVES 104
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 4. Effect of aryl and alkyl Substituents at Position 3 on α-adrenoreceptor blocking activity 103
Design, synthesis and muscarinic activity of deoxamuscarine-related derivatives 103
I recettori adrenergici 102
16th Camerino-Noordwijkerhout Symposium - An Overview of Receptor Chemistry 102
Alpha(2)-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole 101
28th Camerino-Cyprus-Noordwijkerhout Symposium - Trekking through Receptor Chemistry 101
Novel Potent 5-HT1a Agonists Selective over alpha1-Adrenoceptor Subtypes 100
Molecular determinants in the binding of novel 1,4-benzodioxan-related α1D-adrenergic receptor antagonists: a computational study 99
Age-related Changes in the Density of Muscarinic Cholinergic M1 and M2 Receptor Subtypes in Pyramidal Neurons or the rat Hippocampus 99
BIOLOGICAL PROFILE AND BIOAVAILABILITY OF IMIDAZOLINE COMPOUNDS AFFECT THEIR MODULATORY ACTIVITY ON MORPHINE TOLERANCE 99
Rational design of novel I1-imidazoline receptor agonists 97
Allyphenyline analogues potentially useful in the management of chronic pain and opioid addiction. 95
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands 94
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9.From 1,4-benzodioxan to 1,4-dioxane ring as a promising template of novel alpha(1D)-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents. 94
Agonists and antagonists targeting the different alpha(2)-adrenoceptor subtypes 93
Imidazoline nucleus as a biologically versatile scaffold 93
Design and synthesis of novel imidazoline derivatives potentially targeting dopamine receptors 92
Structure-Activity Relationships in 1,4-Benzodioxan-Related Compounds. 6. Role of the Dioxane Unit on Selectivity for Alpha1-Adrenoreceptor Subtypes 92
Byciclic dioxolanes as potential antimuscarinic agents 92
Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel alpha1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and alpha1d computational study 91
Copresence of 1,4-dioxane and quinuclidine nuclei in the design of novel muscarinic antagonists 89
Might adrenergic α2C-agonist/α2A-antagonist become a novel therapeutic multitarget tool for morphine chronic treatment of pain? 89
NOVEL BIVALENT LIGANDS OF XANOMELINE AND 77-LH-28-1 AS POTENTIAL M1 MUSCARINIC AGONISTS 89
Rational design of new alpha(2)-adrenoreceptor agonists 88
Hybrid molecules from xanomeline and 77-LH-28-1 as potential novel M1 muscarinic agonists 86
Aminopyrimidines as inhibitors of the Wnt signalling pathway 86
DOPAMINE D2, D3, AND D4 RECEPTOR AFFINITIES OF 77-LH-28-1 AND ITS ANALOGUES 86
Might the observed alpha2A-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? 85
Enantioselective interactions to improve adrenergic α2C-agonism/α2A-antagonism 85
Enantiomers of 6,6-diphenyl-1,4-dioxane derivatives to highlight stereochemical requirements for selective alpha1D-AR and 5- HT1A receptor recognition 85
NOVEL IMIDAZOLINE MOLECULES INSPIRED BY THE PHARMACOLOGICAL PROFILE OF AGMATINE AS POTENTIAL TOOLS IN MANAGING OPIOID ADDICTION 85
77-LH-28-1 as a model for the rational design of selective dopamine D4 receptor ligands 85
Binding of Tracizolines to the Imidazoline Receptor. Role of Lipophilicity in Quantitative Structure-Activity Relationship Models. 84
Structure- Activity Relationships in 1,4-Benzodioxan-related Compounds. 5. Effects of Modification of the side chain on alpha-adrenoreceptor blocking Activity 83
MORPHINE TOLERANCE MODULATION INDUCED BY alpha2-ADRENERGIC OR/AND I2 IMIDAZOLINE BINDING SITES LIGANDS 83
4WD to Travel Inside the 5-HT1A Receptor World 82
Coupling of I-1 Imidazoline Receptors to the cAMP Pathway: Studies with a Highly Selective Ligand, Benazoline 79
Alpha2C-adrenoceptor modulators: a patent review 77
Novel α1-adrenoreceptor antagonists related to openphendioxan: biological evaluation and α1d computational study 75
Synergic stimulation of serotonin 5-HT1A receptor and α2-adrenoceptors for neuropathic pain relief: Preclinical effects of 2-substituted imidazoline derivatives 74
Novel muscarinic antagonists designed on the 1,4-dioxane scaffold 70
Totale 12.344
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Categoria #
all - tutte 46.391
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.391
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.228 0 79 263 422 139 302 261 253 135 151 55 168
2020/20211.829 96 159 96 189 120 118 207 32 165 86 367 194
2021/20221.135 94 281 14 78 83 61 29 77 86 125 76 131
2022/20231.704 200 67 71 269 183 227 10 105 313 97 108 54
2023/20241.105 167 63 74 33 46 97 45 17 113 40 25 385
2024/2025220 142 78 0 0 0 0 0 0 0 0 0 0
Totale 12.671