GRIFANTINI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 8.415
EU - Europa 3.175
AS - Asia 2.985
SA - Sud America 356
Continente sconosciuto - Info sul continente non disponibili 162
AF - Africa 55
OC - Oceania 5
Totale 15.153
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Nazione #
US - Stati Uniti d'America 8.084
CN - Cina 1.315
SG - Singapore 857
RU - Federazione Russa 791
IT - Italia 454
DE - Germania 408
BR - Brasile 299
SE - Svezia 293
CA - Canada 284
UA - Ucraina 253
FR - Francia 247
GB - Regno Unito 237
HK - Hong Kong 225
VN - Vietnam 196
PL - Polonia 165
FI - Finlandia 146
TR - Turchia 96
KR - Corea 86
IE - Irlanda 59
IN - India 44
CZ - Repubblica Ceca 35
ZA - Sudafrica 35
MX - Messico 29
BD - Bangladesh 28
JP - Giappone 28
EU - Europa 26
IR - Iran 23
BE - Belgio 19
IQ - Iraq 17
AR - Argentina 16
ES - Italia 12
RS - Serbia 10
UZ - Uzbekistan 10
EC - Ecuador 9
NL - Olanda 9
VE - Venezuela 9
CO - Colombia 8
LT - Lituania 8
IL - Israele 7
EG - Egitto 6
PK - Pakistan 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
ID - Indonesia 5
JO - Giordania 5
AT - Austria 4
CL - Cile 4
CR - Costa Rica 4
KE - Kenya 4
NP - Nepal 4
NZ - Nuova Zelanda 4
SA - Arabia Saudita 4
TW - Taiwan 4
UY - Uruguay 4
DZ - Algeria 3
JM - Giamaica 3
KH - Cambogia 3
LB - Libano 3
MA - Marocco 3
MY - Malesia 3
PY - Paraguay 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
BG - Bulgaria 2
BO - Bolivia 2
CH - Svizzera 2
HU - Ungheria 2
PH - Filippine 2
PR - Porto Rico 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BB - Barbados 1
BH - Bahrain 1
BS - Bahamas 1
DK - Danimarca 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
MN - Mongolia 1
MT - Malta 1
NI - Nicaragua 1
NO - Norvegia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
SI - Slovenia 1
TH - Thailandia 1
Totale 15.017
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Città #
Jacksonville 636
Ashburn 627
Fairfield 593
Woodbridge 581
Singapore 458
Chandler 437
Ann Arbor 421
Houston 405
San Jose 397
Dallas 390
Council Bluffs 272
Wilmington 265
Seattle 262
Boardman 248
Nanjing 221
Hong Kong 214
Cambridge 210
Beijing 193
Toronto 170
Kraków 136
The Dalles 130
San Mateo 117
Düsseldorf 111
Los Angeles 108
New York 95
Seoul 82
Columbus 81
Princeton 81
Lawrence 80
Tongling 80
Istanbul 79
Ho Chi Minh City 74
Lauterbourg 73
Dearborn 71
Lachine 70
Nanchang 67
Ogden 63
Helsinki 61
Buffalo 59
Dublin 57
Shenyang 44
Tianjin 44
London 41
Moscow 41
Kunming 40
Hebei 38
Chicago 37
Shanghai 37
Camerino 35
Milan 35
Hanoi 33
Washington 32
Jiaxing 31
Jinan 31
Leawood 31
Guangzhou 30
Johannesburg 30
Venezia 30
São Paulo 28
Santa Clara 27
Orem 25
Redwood City 25
San Diego 24
Warsaw 24
Changsha 22
Tokyo 22
Brno 19
Brussels 19
Montreal 19
Hangzhou 18
Chennai 17
Phoenix 17
Stockholm 17
Augusta 16
Ardabil 15
Dong Ket 15
Wuhan 15
Zhengzhou 15
Falls Church 14
Frankfurt am Main 14
Hefei 14
Munich 14
San Francisco 14
Acquaviva 13
Auburn Hills 13
Mexico City 13
Philadelphia 13
Brooklyn 12
Ningbo 12
Atlanta 11
Denver 11
Manchester 11
Olomouc 11
Rio de Janeiro 11
Rome 11
Venice 11
Verona 11
Changchun 10
Mumbai 10
Da Nang 9
Totale 10.077
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Nome #
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 272
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 259
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 256
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 246
8-Azaxanthine derivatives as antagonists of adenosine receptors. 245
8-Aza-1-deaza purine nucleosides as antiviral agents. 240
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 239
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 238
A new facile synthesis and antiviral activity of oxazofurin 234
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 230
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 230
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 229
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 228
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 226
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 224
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 221
Adenosine receptors as promising targets for the management of ocular diseases 217
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 216
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 216
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 215
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 210
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 209
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 207
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 207
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 207
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 207
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 206
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 206
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 205
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 201
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 200
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 199
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 198
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 196
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 195
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 194
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 193
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 193
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 193
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 192
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 190
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 190
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 189
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 187
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 185
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 184
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 181
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 181
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 180
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 179
Ribose-modified mizoribine analogues: synthesis and biological evaluation 178
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 177
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 176
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 172
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 171
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 171
Tiazofurin analogs as selective agonists of A1 adenosine receptors 167
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 167
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 166
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 166
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 165
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 164
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 164
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 164
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 161
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 155
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 152
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 152
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 148
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 148
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 145
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 142
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 137
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 135
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 134
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 130
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 130
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 130
Tiazofurine ICN Pharmaceuticals 128
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 113
Totale 15.153
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Categoria #
all - tutte 60.570
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.570
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022621 0 0 13 65 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024861 122 45 66 18 49 124 25 27 85 40 11 249
2024/20252.386 105 58 224 96 66 109 323 583 201 155 108 358
2025/20263.235 199 325 397 436 351 282 527 173 108 239 126 72
2026/2027395 216 83 96 0 0 0 0 0 0 0 0 0
Totale 15.153