GRIFANTINI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 6.197
EU - Europa 2.049
AS - Asia 1.245
Continente sconosciuto - Info sul continente non disponibili 26
SA - Sud America 9
OC - Oceania 4
AF - Africa 2
Totale 9.532
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Nazione #
US - Stati Uniti d'America 5.955
CN - Cina 934
IT - Italia 410
DE - Germania 365
SE - Svezia 278
UA - Ucraina 247
CA - Canada 240
GB - Regno Unito 207
FR - Francia 146
PL - Polonia 139
SG - Singapore 139
FI - Finlandia 117
TR - Turchia 85
IE - Irlanda 55
CZ - Repubblica Ceca 34
EU - Europa 26
IR - Iran 23
BE - Belgio 19
IN - India 18
VN - Vietnam 16
RS - Serbia 9
JP - Giappone 6
HK - Hong Kong 5
KR - Corea 5
RO - Romania 5
CL - Cile 4
NL - Olanda 4
KH - Cambogia 3
NZ - Nuova Zelanda 3
RU - Federazione Russa 3
AR - Argentina 2
BR - Brasile 2
CH - Svizzera 2
ES - Italia 2
IL - Israele 2
PK - Pakistan 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AU - Australia 1
AZ - Azerbaigian 1
BS - Bahamas 1
EC - Ecuador 1
EE - Estonia 1
EG - Egitto 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
JO - Giordania 1
LB - Libano 1
LK - Sri Lanka 1
LT - Lituania 1
MA - Marocco 1
NO - Norvegia 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 9.532
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Città #
Jacksonville 636
Fairfield 593
Woodbridge 581
Chandler 437
Ann Arbor 421
Ashburn 401
Houston 395
Wilmington 260
Seattle 259
Boardman 248
Nanjing 221
Cambridge 210
Toronto 162
Kraków 136
San Mateo 117
Düsseldorf 103
Singapore 90
Lawrence 80
Princeton 80
Columbus 77
Istanbul 75
Dearborn 71
Lachine 70
Nanchang 67
Beijing 64
Ogden 63
Dublin 53
New York 45
Shenyang 44
Tianjin 41
Kunming 40
Hebei 38
Helsinki 38
Camerino 35
London 33
Shanghai 32
Jiaxing 31
Leawood 31
Jinan 30
Milan 30
Venezia 30
Washington 30
Guangzhou 27
Redwood City 25
Los Angeles 24
San Diego 24
Brno 19
Brussels 19
Changsha 18
Hangzhou 18
Ardabil 15
Augusta 15
Chicago 15
Dong Ket 15
Zhengzhou 15
Falls Church 14
Hefei 14
Wuhan 14
Acquaviva 13
Auburn Hills 13
Philadelphia 12
Venice 11
Verona 11
Changchun 10
Ningbo 10
Olomouc 10
Jinhua 9
Norwalk 9
Lanzhou 8
Monmouth Junction 8
Mumbai 8
Nürnberg 8
Taizhou 8
Yiwu 8
Bremen 7
Kocaeli 7
Macerata 7
Shenzhen 7
Belgrade 6
Fuzhou 6
Munich 6
Orange 6
Perugia 6
Casette 5
Edinburgh 5
Prague 5
Strasbourg 5
Zanjan 5
Andover 4
Ardea 4
Council Bluffs 4
Gunzenhausen 4
Iesi 4
Indiana 4
San Francisco 4
Simi Valley 4
Tampa 4
Timisoara 4
Auckland 3
Berlin 3
Totale 7.074
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Nome #
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 185
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 180
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 179
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 173
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 165
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 165
8-Azaxanthine derivatives as antagonists of adenosine receptors. 162
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 159
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 159
8-Aza-1-deaza purine nucleosides as antiviral agents. 154
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 154
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 148
A new facile synthesis and antiviral activity of oxazofurin 146
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 145
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 145
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 143
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 143
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 142
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 141
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 141
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 140
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 139
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 139
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 138
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 136
Ribose-modified mizoribine analogues: synthesis and biological evaluation 135
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 135
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 134
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 134
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 132
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 131
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 131
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 129
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 126
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 126
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 125
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 124
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 124
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 124
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 120
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 120
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 119
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 118
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 118
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 115
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 114
Adenosine receptors as promising targets for the management of ocular diseases 113
Tiazofurin analogs as selective agonists of A1 adenosine receptors 112
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 112
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 112
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 112
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 110
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 108
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 106
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 105
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 104
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 102
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 101
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 100
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 100
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 97
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 96
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 96
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 95
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 94
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 92
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 89
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 89
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 88
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 87
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 87
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 85
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 84
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 83
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 78
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 78
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 78
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 75
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 74
Tiazofurine ICN Pharmaceuticals 71
Totale 9.668
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Categoria #
all - tutte 38.718
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.718
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020982 0 0 0 0 96 174 152 183 123 109 34 111
2020/20211.285 33 106 56 102 75 74 148 21 116 32 352 170
2021/2022911 69 221 13 65 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024861 122 45 66 18 49 124 25 27 85 40 11 249
2024/2025531 105 58 224 96 48 0 0 0 0 0 0 0
Totale 9.668