GRIFANTINI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 7.902
EU - Europa 3.154
AS - Asia 2.930
SA - Sud America 352
AF - Africa 55
Continente sconosciuto - Info sul continente non disponibili 26
OC - Oceania 5
Totale 14.424
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Nazione #
US - Stati Uniti d'America 7.594
CN - Cina 1.289
SG - Singapore 843
RU - Federazione Russa 791
IT - Italia 439
DE - Germania 408
BR - Brasile 297
SE - Svezia 293
CA - Canada 272
UA - Ucraina 253
FR - Francia 246
GB - Regno Unito 236
HK - Hong Kong 222
VN - Vietnam 194
PL - Polonia 164
FI - Finlandia 146
TR - Turchia 96
KR - Corea 86
IE - Irlanda 59
IN - India 44
CZ - Repubblica Ceca 35
ZA - Sudafrica 35
JP - Giappone 28
MX - Messico 27
EU - Europa 26
IR - Iran 23
BD - Bangladesh 22
BE - Belgio 19
IQ - Iraq 17
AR - Argentina 16
ES - Italia 11
RS - Serbia 10
UZ - Uzbekistan 10
EC - Ecuador 9
NL - Olanda 9
CO - Colombia 8
LT - Lituania 8
VE - Venezuela 8
IL - Israele 7
EG - Egitto 6
PK - Pakistan 6
RO - Romania 6
ID - Indonesia 5
JO - Giordania 5
AE - Emirati Arabi Uniti 4
AT - Austria 4
CL - Cile 4
KE - Kenya 4
NZ - Nuova Zelanda 4
SA - Arabia Saudita 4
TW - Taiwan 4
UY - Uruguay 4
DZ - Algeria 3
KH - Cambogia 3
LB - Libano 3
MA - Marocco 3
NP - Nepal 3
TN - Tunisia 3
BG - Bulgaria 2
BO - Bolivia 2
CH - Svizzera 2
HU - Ungheria 2
JM - Giamaica 2
PH - Filippine 2
PT - Portogallo 2
PY - Paraguay 2
TT - Trinidad e Tobago 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BH - Bahrain 1
BS - Bahamas 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
MN - Mongolia 1
MT - Malta 1
MY - Malesia 1
NI - Nicaragua 1
NO - Norvegia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
Totale 14.424
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Città #
Jacksonville 636
Ashburn 607
Fairfield 593
Woodbridge 581
Singapore 448
Chandler 437
Ann Arbor 421
Houston 403
Dallas 386
San Jose 348
Wilmington 262
Seattle 260
Boardman 248
Nanjing 221
Hong Kong 211
Cambridge 210
Beijing 185
Toronto 167
Kraków 136
The Dalles 130
San Mateo 117
Düsseldorf 111
Los Angeles 99
New York 91
Seoul 82
Columbus 81
Lawrence 80
Princeton 80
Tongling 80
Istanbul 79
Ho Chi Minh City 74
Lauterbourg 73
Dearborn 71
Lachine 70
Nanchang 67
Ogden 63
Helsinki 61
Dublin 57
Buffalo 55
Shenyang 44
Tianjin 43
London 41
Moscow 41
Kunming 40
Hebei 38
Chicago 36
Shanghai 36
Camerino 35
Milan 34
Hanoi 33
Jiaxing 31
Jinan 31
Leawood 31
Washington 31
Guangzhou 30
Johannesburg 30
Venezia 30
São Paulo 28
Redwood City 25
San Diego 24
Warsaw 24
Orem 23
Changsha 22
Tokyo 22
Brno 19
Brussels 19
Santa Clara 19
Hangzhou 18
Chennai 17
Stockholm 17
Augusta 16
Montreal 16
Ardabil 15
Dong Ket 15
Wuhan 15
Zhengzhou 15
Council Bluffs 14
Falls Church 14
Frankfurt am Main 14
Hefei 14
Munich 14
Acquaviva 13
Auburn Hills 13
Mexico City 12
Ningbo 12
Philadelphia 12
Manchester 11
Olomouc 11
Rio de Janeiro 11
San Francisco 11
Venice 11
Verona 11
Atlanta 10
Brooklyn 10
Changchun 10
Mumbai 10
Phoenix 10
Da Nang 9
Jinhua 9
Macerata 9
Totale 9.660
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Nome #
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 264
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 253
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 248
8-Azaxanthine derivatives as antagonists of adenosine receptors. 242
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 238
8-Aza-1-deaza purine nucleosides as antiviral agents. 234
A new facile synthesis and antiviral activity of oxazofurin 230
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 230
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 228
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 225
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 223
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 222
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 219
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 215
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 213
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 211
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 210
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 209
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 208
Adenosine receptors as promising targets for the management of ocular diseases 207
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 202
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 201
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 200
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 199
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 197
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 197
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 196
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 195
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 194
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 193
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 192
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 191
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 190
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 190
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 190
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 189
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 187
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 187
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 185
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 184
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 184
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 182
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 181
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 181
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 179
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 178
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 177
Ribose-modified mizoribine analogues: synthesis and biological evaluation 174
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 174
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 171
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 171
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 168
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 167
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 164
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 163
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 163
Tiazofurin analogs as selective agonists of A1 adenosine receptors 162
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 160
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 159
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 159
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 158
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 157
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 157
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 157
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 157
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 147
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 144
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 143
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 141
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 141
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 138
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 136
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 129
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 126
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 126
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 125
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 122
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 121
Tiazofurine ICN Pharmaceuticals 121
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 109
Totale 14.560
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Categoria #
all - tutte 55.840
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.840
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021554 0 0 0 0 0 0 0 0 0 32 352 170
2021/2022911 69 221 13 65 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024861 122 45 66 18 49 124 25 27 85 40 11 249
2024/20252.386 105 58 224 96 66 109 323 583 201 155 108 358
2025/20263.037 199 325 397 436 351 282 527 173 108 239 0 0
Totale 14.560