GRIFANTINI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 5.989
EU - Europa 2.028
AS - Asia 1.109
Continente sconosciuto - Info sul continente non disponibili 26
SA - Sud America 7
OC - Oceania 3
AF - Africa 1
Totale 9.163
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Nazione #
US - Stati Uniti d'America 5.751
CN - Cina 928
IT - Italia 404
DE - Germania 364
SE - Svezia 277
UA - Ucraina 247
CA - Canada 236
GB - Regno Unito 207
FR - Francia 146
PL - Polonia 139
FI - Finlandia 115
SG - Singapore 91
IE - Irlanda 55
CZ - Repubblica Ceca 33
EU - Europa 26
IR - Iran 23
BE - Belgio 18
IN - India 18
VN - Vietnam 16
TR - Turchia 11
RS - Serbia 9
JP - Giappone 5
KR - Corea 5
RO - Romania 5
CL - Cile 4
HK - Hong Kong 3
KH - Cambogia 3
NZ - Nuova Zelanda 3
AR - Argentina 2
CH - Svizzera 2
PK - Pakistan 2
RU - Federazione Russa 2
BR - Brasile 1
BS - Bahamas 1
ES - Italia 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
IL - Israele 1
JO - Giordania 1
LB - Libano 1
MA - Marocco 1
NL - Olanda 1
NO - Norvegia 1
TW - Taiwan 1
Totale 9.163
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Città #
Jacksonville 636
Fairfield 593
Woodbridge 581
Chandler 437
Ann Arbor 421
Houston 395
Ashburn 381
Wilmington 260
Seattle 259
Nanjing 221
Cambridge 210
Toronto 159
Kraków 136
San Mateo 117
Düsseldorf 103
Boardman 88
Lawrence 80
Princeton 80
Columbus 77
Dearborn 71
Lachine 70
Nanchang 67
Beijing 63
Ogden 63
Singapore 55
Dublin 53
New York 44
Shenyang 44
Tianjin 41
Kunming 40
Hebei 38
Helsinki 38
Camerino 34
London 33
Jiaxing 31
Leawood 31
Shanghai 31
Jinan 30
Venezia 30
Washington 30
Milan 29
Guangzhou 27
Redwood City 25
San Diego 24
Brno 19
Los Angeles 19
Brussels 18
Changsha 18
Hangzhou 18
Ardabil 15
Augusta 15
Chicago 15
Dong Ket 15
Zhengzhou 15
Falls Church 14
Hefei 14
Wuhan 14
Acquaviva 13
Auburn Hills 13
Philadelphia 12
Venice 11
Verona 11
Changchun 10
Ningbo 10
Olomouc 10
Jinhua 9
Norwalk 9
Lanzhou 8
Monmouth Junction 8
Mumbai 8
Nürnberg 8
Taizhou 8
Yiwu 8
Bremen 7
Kocaeli 7
Macerata 7
Belgrade 6
Fuzhou 6
Munich 6
Orange 6
Perugia 6
Shenzhen 6
Casette 5
Edinburgh 5
Strasbourg 5
Zanjan 5
Andover 4
Ardea 4
Council Bluffs 4
Gunzenhausen 4
Iesi 4
Indiana 4
Prague 4
San Francisco 4
Simi Valley 4
Tampa 4
Timisoara 4
Auckland 3
Berlin 3
Bologna 3
Totale 6.771
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Nome #
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 182
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 175
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 174
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 170
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 160
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 159
8-Azaxanthine derivatives as antagonists of adenosine receptors. 157
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 155
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 152
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 151
8-Aza-1-deaza purine nucleosides as antiviral agents. 148
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 145
A new facile synthesis and antiviral activity of oxazofurin 142
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 142
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 141
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 141
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 138
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 138
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 138
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 137
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 137
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 136
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 136
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 135
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 132
Ribose-modified mizoribine analogues: synthesis and biological evaluation 131
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 130
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 130
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 129
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 128
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 127
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 127
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 126
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 122
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 121
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 120
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 120
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 116
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 116
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 116
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 115
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 115
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 115
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 111
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 111
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 109
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 109
Tiazofurin analogs as selective agonists of A1 adenosine receptors 108
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 106
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 105
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 104
Adenosine receptors as promising targets for the management of ocular diseases 104
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 102
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 101
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 100
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 99
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 98
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 97
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 97
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 94
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 92
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 91
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 91
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 89
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 88
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 87
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 86
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 84
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 84
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 84
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 82
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 81
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 80
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 78
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 74
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 73
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 71
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 71
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 67
Tiazofurine ICN Pharmaceuticals 66
Totale 9.299
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Categoria #
all - tutte 34.958
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.958
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.637 0 70 203 382 96 174 152 183 123 109 34 111
2020/20211.285 33 106 56 102 75 74 148 21 116 32 352 170
2021/2022911 69 221 13 65 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024861 122 45 66 18 49 124 25 27 85 40 11 249
2024/2025162 105 57 0 0 0 0 0 0 0 0 0 0
Totale 9.299