GRIFANTINI, Mario
 Distribuzione geografica
Continente #
NA - Nord America 9.283
EU - Europa 3.273
AS - Asia 3.020
SA - Sud America 373
Continente sconosciuto - Info sul continente non disponibili 166
AF - Africa 66
OC - Oceania 5
Totale 16.186
Nazione #
US - Stati Uniti d'America 8.890
CN - Cina 1.318
SG - Singapore 858
RU - Federazione Russa 809
IT - Italia 504
DE - Germania 415
BR - Brasile 315
CA - Canada 299
SE - Svezia 293
UA - Ucraina 257
GB - Regno Unito 249
FR - Francia 248
HK - Hong Kong 225
VN - Vietnam 197
PL - Polonia 166
FI - Finlandia 146
TR - Turchia 97
KR - Corea 86
IE - Irlanda 59
IN - India 45
CZ - Repubblica Ceca 35
ZA - Sudafrica 35
BD - Bangladesh 30
JP - Giappone 30
MX - Messico 29
EU - Europa 26
IL - Israele 25
IR - Iran 23
BE - Belgio 19
AR - Argentina 17
IQ - Iraq 17
CR - Costa Rica 14
ES - Italia 13
NL - Olanda 12
SC - Seychelles 11
RS - Serbia 10
UZ - Uzbekistan 10
EC - Ecuador 9
VE - Venezuela 9
CO - Colombia 8
LT - Lituania 8
PR - Porto Rico 8
HN - Honduras 7
PK - Pakistan 7
SV - El Salvador 7
TT - Trinidad e Tobago 7
EG - Egitto 6
JM - Giamaica 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
GT - Guatemala 5
ID - Indonesia 5
JO - Giordania 5
NI - Nicaragua 5
NP - Nepal 5
AT - Austria 4
CL - Cile 4
CW - ???statistics.table.value.countryCode.CW??? 4
KE - Kenya 4
MY - Malesia 4
NZ - Nuova Zelanda 4
SA - Arabia Saudita 4
TW - Taiwan 4
UY - Uruguay 4
DZ - Algeria 3
KH - Cambogia 3
LB - Libano 3
MA - Marocco 3
PY - Paraguay 3
TN - Tunisia 3
AM - Armenia 2
BG - Bulgaria 2
BO - Bolivia 2
CH - Svizzera 2
EE - Estonia 2
HU - Ungheria 2
PH - Filippine 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AU - Australia 1
AZ - Azerbaigian 1
BB - Barbados 1
BH - Bahrain 1
BS - Bahamas 1
DK - Danimarca 1
DM - Dominica 1
ET - Etiopia 1
GP - Guadalupe 1
GY - Guiana 1
HR - Croazia 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
MN - Mongolia 1
MQ - Martinica 1
MT - Malta 1
Totale 16.044
Città #
Ashburn 855
Jacksonville 636
Fairfield 594
Woodbridge 581
Singapore 459
San Jose 448
Chandler 437
Ann Arbor 421
Houston 409
Dallas 395
Council Bluffs 273
Wilmington 265
Seattle 263
Boardman 249
Nanjing 221
Hong Kong 214
Cambridge 210
Beijing 193
Toronto 173
Kraków 136
New York 133
The Dalles 130
San Mateo 117
Los Angeles 113
Düsseldorf 111
Princeton 107
Columbus 82
Seoul 82
Lawrence 80
Tongling 80
Istanbul 79
Ho Chi Minh City 75
Lauterbourg 73
Dearborn 71
Lachine 70
Nanchang 67
Chicago 66
Buffalo 64
Washington 64
Ogden 63
Helsinki 61
Dublin 57
Shenyang 44
Tianjin 44
London 42
Milan 41
Moscow 41
Kunming 40
Hebei 38
Shanghai 37
São Paulo 37
Santa Clara 36
Camerino 35
Hanoi 33
Jiaxing 31
Jinan 31
Leawood 31
Guangzhou 30
Johannesburg 30
Venezia 30
Orem 25
Phoenix 25
Redwood City 25
San Diego 24
Tokyo 24
Warsaw 24
Changsha 22
Montreal 20
Brno 19
Brussels 19
Hangzhou 18
Chennai 17
Stockholm 17
Augusta 16
San Francisco 16
Ardabil 15
Atlanta 15
Brooklyn 15
Denver 15
Dong Ket 15
Philadelphia 15
Rome 15
Wuhan 15
Zhengzhou 15
Falls Church 14
Frankfurt am Main 14
Hefei 14
Munich 14
Acquaviva 13
Auburn Hills 13
Mexico City 13
Manchester 12
Ningbo 12
Venice 12
Verona 12
Charlotte 11
Indianapolis 11
Olomouc 11
Rio de Janeiro 11
San José 11
Totale 10.572
Nome #
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 284
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 277
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 270
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 265
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 256
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 254
8-Azaxanthine derivatives as antagonists of adenosine receptors. 254
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 253
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 249
8-Aza-1-deaza purine nucleosides as antiviral agents. 249
A new facile synthesis and antiviral activity of oxazofurin 243
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 241
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 239
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 239
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 234
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 231
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 230
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 230
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 230
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 229
Adenosine receptors as promising targets for the management of ocular diseases 228
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 225
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 221
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 221
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 220
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 219
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 217
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 217
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 216
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 212
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 211
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 211
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 211
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 207
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 206
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 205
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 205
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 204
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 204
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 203
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 202
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 201
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 200
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 200
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 197
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 196
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 195
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 193
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 192
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 192
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 190
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 190
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 189
Ribose-modified mizoribine analogues: synthesis and biological evaluation 188
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 182
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 182
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 182
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 182
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 181
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 179
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 177
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 177
Tiazofurin analogs as selective agonists of A1 adenosine receptors 173
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 171
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 171
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 166
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 166
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 165
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 159
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 159
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 159
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 154
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 153
Tiazofurine ICN Pharmaceuticals 153
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 152
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 151
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 150
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 139
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 137
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 121
Totale 16.186
Categoria #
all - tutte 63.933
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 63.933


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022543 0 0 0 0 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024861 122 45 66 18 49 124 25 27 85 40 11 249
2024/20252.386 105 58 224 96 66 109 323 583 201 155 108 358
2025/20263.235 199 325 397 436 351 282 527 173 108 239 126 72
2026/20271.428 216 83 310 667 152 0 0 0 0 0 0 0
Totale 16.186