GRIFANTINI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 7.370
EU - Europa 2.999
AS - Asia 2.571
SA - Sud America 338
AF - Africa 28
Continente sconosciuto - Info sul continente non disponibili 26
OC - Oceania 5
Totale 13.337
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Nazione #
US - Stati Uniti d'America 7.075
CN - Cina 1.242
RU - Federazione Russa 790
SG - Singapore 696
IT - Italia 417
DE - Germania 401
SE - Svezia 293
BR - Brasile 288
CA - Canada 266
UA - Ucraina 249
GB - Regno Unito 229
HK - Hong Kong 206
FR - Francia 165
PL - Polonia 162
FI - Finlandia 127
TR - Turchia 94
KR - Corea 86
VN - Vietnam 77
IE - Irlanda 56
CZ - Repubblica Ceca 35
IN - India 35
EU - Europa 26
IR - Iran 23
JP - Giappone 23
MX - Messico 22
BE - Belgio 19
BD - Bangladesh 18
AR - Argentina 14
IQ - Iraq 14
ZA - Sudafrica 11
ES - Italia 10
RS - Serbia 10
EC - Ecuador 9
NL - Olanda 9
CO - Colombia 8
IL - Israele 7
UZ - Uzbekistan 7
VE - Venezuela 7
LT - Lituania 6
JO - Giordania 5
PK - Pakistan 5
RO - Romania 5
AE - Emirati Arabi Uniti 4
AT - Austria 4
CL - Cile 4
EG - Egitto 4
ID - Indonesia 4
KE - Kenya 4
NZ - Nuova Zelanda 4
SA - Arabia Saudita 4
TW - Taiwan 4
DZ - Algeria 3
KH - Cambogia 3
LB - Libano 3
NP - Nepal 3
TN - Tunisia 3
UY - Uruguay 3
BO - Bolivia 2
CH - Svizzera 2
MA - Marocco 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AU - Australia 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LV - Lettonia 1
MN - Mongolia 1
MT - Malta 1
MY - Malesia 1
NI - Nicaragua 1
NO - Norvegia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
PT - Portogallo 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
TT - Trinidad e Tobago 1
Totale 13.337
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Città #
Jacksonville 636
Fairfield 593
Woodbridge 581
Ashburn 547
Chandler 437
Ann Arbor 421
Houston 403
Dallas 386
Singapore 304
Wilmington 262
Seattle 260
Boardman 248
Nanjing 221
Cambridge 210
Hong Kong 197
Beijing 178
Toronto 167
Kraków 136
San Mateo 117
Düsseldorf 111
The Dalles 104
Los Angeles 96
New York 85
Seoul 82
Columbus 81
Lawrence 80
Princeton 80
Tongling 80
Istanbul 77
Dearborn 71
Lachine 70
Nanchang 67
Ogden 63
Dublin 54
Buffalo 51
Shenyang 44
Tianjin 43
Helsinki 42
Kunming 40
London 40
Moscow 40
Hebei 38
Camerino 35
Chicago 35
Shanghai 34
Jiaxing 31
Jinan 31
Leawood 31
Milan 31
Washington 31
Guangzhou 30
Venezia 30
Ho Chi Minh City 26
São Paulo 26
Redwood City 25
San Diego 24
Changsha 22
Warsaw 22
Brno 19
Brussels 19
Hangzhou 18
Tokyo 18
Stockholm 17
Augusta 16
Ardabil 15
Dong Ket 15
Montreal 15
Wuhan 15
Zhengzhou 15
Falls Church 14
Hefei 14
Munich 14
Acquaviva 13
Auburn Hills 13
Ningbo 12
Philadelphia 12
Council Bluffs 11
Olomouc 11
Orem 11
Venice 11
Verona 11
Brooklyn 10
Changchun 10
Frankfurt am Main 10
Hanoi 10
Phoenix 10
Rio de Janeiro 10
San Francisco 10
Atlanta 9
Chennai 9
Jinhua 9
Mexico City 9
Mumbai 9
Norwalk 9
Ankara 8
Denver 8
Lanzhou 8
Monmouth Junction 8
Nürnberg 8
Shenzhen 8
Totale 8.808
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Nome #
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 250
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 236
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 231
8-Azaxanthine derivatives as antagonists of adenosine receptors. 225
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 222
8-Aza-1-deaza purine nucleosides as antiviral agents. 220
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 219
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 215
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 214
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 213
A new facile synthesis and antiviral activity of oxazofurin 213
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 203
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 203
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 200
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 199
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 199
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 191
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 191
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 191
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 189
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 188
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 187
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 184
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 182
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 182
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 180
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 179
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 179
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 178
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 178
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 178
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 178
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 177
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 176
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 175
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 175
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 175
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 175
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 173
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 172
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 171
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 171
Ribose-modified mizoribine analogues: synthesis and biological evaluation 171
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 171
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 171
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 169
Adenosine receptors as promising targets for the management of ocular diseases 169
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 159
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 159
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 159
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 157
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 156
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 154
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 153
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 151
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 149
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 148
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 147
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 147
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 145
Tiazofurin analogs as selective agonists of A1 adenosine receptors 144
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 144
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 144
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 142
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 137
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 133
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 132
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 132
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 129
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 129
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 122
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 121
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 119
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 117
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 116
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 113
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 112
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 108
Tiazofurine ICN Pharmaceuticals 107
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 100
Totale 13.473
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Categoria #
all - tutte 53.612
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.612
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021913 0 0 0 0 0 74 148 21 116 32 352 170
2021/2022911 69 221 13 65 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024861 122 45 66 18 49 124 25 27 85 40 11 249
2024/20252.386 105 58 224 96 66 109 323 583 201 155 108 358
2025/20261.950 199 325 397 436 351 242 0 0 0 0 0 0
Totale 13.473