GRIFANTINI, Mario
 Distribuzione geografica
Continente #
NA - Nord America 8.242
EU - Europa 3.162
AS - Asia 2.961
SA - Sud America 355
AF - Africa 55
Continente sconosciuto - Info sul continente non disponibili 26
OC - Oceania 5
Totale 14.806
Nazione #
US - Stati Uniti d'America 7.927
CN - Cina 1.304
SG - Singapore 852
RU - Federazione Russa 791
IT - Italia 442
DE - Germania 408
BR - Brasile 299
SE - Svezia 293
CA - Canada 277
UA - Ucraina 253
FR - Francia 246
GB - Regno Unito 237
HK - Hong Kong 224
VN - Vietnam 195
PL - Polonia 165
FI - Finlandia 146
TR - Turchia 96
KR - Corea 86
IE - Irlanda 59
IN - India 44
CZ - Repubblica Ceca 35
ZA - Sudafrica 35
MX - Messico 29
JP - Giappone 28
EU - Europa 26
BD - Bangladesh 23
IR - Iran 23
BE - Belgio 19
IQ - Iraq 17
AR - Argentina 16
ES - Italia 12
RS - Serbia 10
UZ - Uzbekistan 10
EC - Ecuador 9
NL - Olanda 9
CO - Colombia 8
LT - Lituania 8
VE - Venezuela 8
IL - Israele 7
EG - Egitto 6
PK - Pakistan 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
ID - Indonesia 5
JO - Giordania 5
AT - Austria 4
CL - Cile 4
KE - Kenya 4
NP - Nepal 4
NZ - Nuova Zelanda 4
SA - Arabia Saudita 4
TW - Taiwan 4
UY - Uruguay 4
DZ - Algeria 3
KH - Cambogia 3
LB - Libano 3
MA - Marocco 3
PY - Paraguay 3
TN - Tunisia 3
BG - Bulgaria 2
BO - Bolivia 2
CH - Svizzera 2
HU - Ungheria 2
JM - Giamaica 2
MY - Malesia 2
PH - Filippine 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
TT - Trinidad e Tobago 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BH - Bahrain 1
BS - Bahamas 1
DK - Danimarca 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
MN - Mongolia 1
MT - Malta 1
NI - Nicaragua 1
NO - Norvegia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
SI - Slovenia 1
TH - Thailandia 1
Totale 14.806
Città #
Jacksonville 636
Ashburn 616
Fairfield 593
Woodbridge 581
Singapore 453
Chandler 437
Ann Arbor 421
Houston 404
Dallas 388
San Jose 358
Council Bluffs 272
Wilmington 263
Seattle 261
Boardman 248
Nanjing 221
Hong Kong 213
Cambridge 210
Beijing 186
Toronto 169
Kraków 136
The Dalles 130
San Mateo 117
Düsseldorf 111
Los Angeles 102
New York 94
Seoul 82
Columbus 81
Lawrence 80
Princeton 80
Tongling 80
Istanbul 79
Ho Chi Minh City 74
Lauterbourg 73
Dearborn 71
Lachine 70
Nanchang 67
Ogden 63
Helsinki 61
Buffalo 57
Dublin 57
Shenyang 44
Tianjin 44
London 41
Moscow 41
Kunming 40
Hebei 38
Chicago 36
Shanghai 36
Camerino 35
Milan 34
Hanoi 33
Jiaxing 31
Jinan 31
Leawood 31
Washington 31
Guangzhou 30
Johannesburg 30
Venezia 30
São Paulo 28
Orem 25
Redwood City 25
San Diego 24
Santa Clara 24
Warsaw 24
Changsha 22
Tokyo 22
Brno 19
Brussels 19
Hangzhou 18
Chennai 17
Montreal 17
Stockholm 17
Augusta 16
Ardabil 15
Dong Ket 15
Wuhan 15
Zhengzhou 15
Falls Church 14
Frankfurt am Main 14
Hefei 14
Munich 14
Acquaviva 13
Auburn Hills 13
Mexico City 13
San Francisco 13
Brooklyn 12
Ningbo 12
Philadelphia 12
Atlanta 11
Manchester 11
Olomouc 11
Phoenix 11
Rio de Janeiro 11
Venice 11
Verona 11
Changchun 10
Mumbai 10
Da Nang 9
Denver 9
Jinhua 9
Totale 9.976
Nome #
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 272
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 255
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 253
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 244
8-Azaxanthine derivatives as antagonists of adenosine receptors. 244
8-Aza-1-deaza purine nucleosides as antiviral agents. 238
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 235
A new facile synthesis and antiviral activity of oxazofurin 234
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 234
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 229
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 228
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 225
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 225
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 224
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 222
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 220
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 215
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 214
Adenosine receptors as promising targets for the management of ocular diseases 214
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 212
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 206
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 206
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 206
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 205
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 204
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 202
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 202
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 201
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 197
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 197
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 197
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 195
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 194
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 193
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 193
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 192
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 191
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 191
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 191
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 191
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 190
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 188
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 187
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 186
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 182
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 181
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 181
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 180
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 178
Ribose-modified mizoribine analogues: synthesis and biological evaluation 177
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 174
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 173
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 173
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 171
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 167
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 167
Tiazofurin analogs as selective agonists of A1 adenosine receptors 165
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 163
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 163
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 163
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 162
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 161
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 161
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 160
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 160
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 154
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 149
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 148
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 146
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 145
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 142
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 139
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 134
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 132
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 130
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 129
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 127
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 126
Tiazofurine ICN Pharmaceuticals 125
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 112
Totale 14.942
Categoria #
all - tutte 58.653
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.653


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022911 69 221 13 65 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024861 122 45 66 18 49 124 25 27 85 40 11 249
2024/20252.386 105 58 224 96 66 109 323 583 201 155 108 358
2025/20263.235 199 325 397 436 351 282 527 173 108 239 126 72
2026/2027184 184 0 0 0 0 0 0 0 0 0 0 0
Totale 14.942