GRIFANTINI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 5.940
EU - Europa 1.989
AS - Asia 775
Continente sconosciuto - Info sul continente non disponibili 26
SA - Sud America 7
OC - Oceania 3
AF - Africa 1
Totale 8.741
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Nazione #
US - Stati Uniti d'America 5.702
CN - Cina 687
IT - Italia 400
DE - Germania 359
SE - Svezia 277
UA - Ucraina 247
CA - Canada 236
GB - Regno Unito 207
FR - Francia 146
PL - Polonia 139
FI - Finlandia 114
IE - Irlanda 55
EU - Europa 26
IR - Iran 23
BE - Belgio 18
IN - India 18
VN - Vietnam 16
TR - Turchia 11
RS - Serbia 9
JP - Giappone 5
RO - Romania 5
CL - Cile 4
CZ - Repubblica Ceca 4
KR - Corea 4
KH - Cambogia 3
NZ - Nuova Zelanda 3
AR - Argentina 2
CH - Svizzera 2
HK - Hong Kong 2
PK - Pakistan 2
RU - Federazione Russa 2
BR - Brasile 1
BS - Bahamas 1
ES - Italia 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
IL - Israele 1
JO - Giordania 1
LB - Libano 1
MA - Marocco 1
NL - Olanda 1
NO - Norvegia 1
SG - Singapore 1
Totale 8.741
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Città #
Jacksonville 636
Fairfield 593
Woodbridge 581
Chandler 437
Ann Arbor 421
Houston 395
Ashburn 371
Wilmington 260
Seattle 259
Nanjing 216
Cambridge 210
Toronto 159
Kraków 136
San Mateo 117
Düsseldorf 103
Lawrence 80
Princeton 80
Columbus 77
Boardman 74
Dearborn 71
Lachine 70
Nanchang 67
Ogden 63
Dublin 53
Beijing 48
New York 44
Shenyang 44
Tianjin 41
Kunming 40
Hebei 38
Helsinki 37
London 33
Camerino 32
Leawood 31
Venezia 30
Washington 30
Milan 29
Jinan 28
Redwood City 25
San Diego 24
Brussels 18
Changsha 18
Jiaxing 18
Hangzhou 17
Ardabil 15
Augusta 15
Dong Ket 15
Zhengzhou 15
Falls Church 14
Hefei 14
Shanghai 14
Acquaviva 13
Auburn Hills 13
Los Angeles 12
Philadelphia 12
Venice 11
Verona 11
Changchun 10
Ningbo 9
Norwalk 9
Lanzhou 8
Monmouth Junction 8
Mumbai 8
Nürnberg 8
Bremen 7
Kocaeli 7
Macerata 7
Taizhou 7
Belgrade 6
Fuzhou 6
Guangzhou 6
Orange 6
Perugia 6
Casette 5
Edinburgh 5
Strasbourg 5
Zanjan 5
Andover 4
Ardea 4
Council Bluffs 4
Gunzenhausen 4
Iesi 4
Indiana 4
Prague 4
San Francisco 4
Simi Valley 4
Tampa 4
Timisoara 4
Auckland 3
Berlin 3
Bologna 3
Buffalo 3
Chengdu 3
Chicago 3
Fossombrone 3
Hiroshima 3
Hounslow 3
Indianapolis 3
Lambeth 3
Nanning 3
Totale 6.546
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Nome #
Development of C-Methyl Branched Purine Ribonucleoside Analogs: Chemistry, Biological Activity and Therapeutic Potential 178
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors 168
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(Phosphono-methoxy)propyl]guanines. 167
8-Aza analogues of deaza purine nucleosides. Synthesis and biological evaluation of 8-aza-1-deazaadenosine and 2'-deoxy-8-aza-1-deazaadenosine 165
Targeting Nucleotide Dimers Containing Antiviral Nucleosides 154
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. 152
Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents 152
8-Azaxanthine derivatives as antagonists of adenosine receptors. 149
Purine and pyrimidine nucleoside analogs of 3'-C-methyladenosine as antitumor agents 146
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir 145
Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate dehydrogenase (Type I and II) Inhibitors 141
8-Aza-1-deaza purine nucleosides as antiviral agents. 140
Synthesis and evaluation of anti-HIV-1 and antitumor activity of 2',3'-didehydro-2',3'-dideoxy-3-deazaadenosine, 2',3'-dideoxy-3-deazaadenosine and some 2',3'-dideoxy-3-deazaadenosine 5'-dialkyl phosphates 138
Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine 137
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746. 136
A new facile synthesis and antiviral activity of oxazofurin 135
Acyclic nucleotides related to clitocine: synthesis and anti-HIV activity 134
Synthesis and antitumor activity of a heterodinucleotide of BVDU and Gemcitabine 133
Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin 133
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity 133
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 133
Synthesis, antitumor activity and crystallographic studies of analogues of tiazofurin 132
Preparation of purine and 8-azapurine derivatives for treatment of acquired immune deficiency syndrome. 131
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation 129
Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase 128
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3’-C-methyladenosine in leukaemia cells 128
Synthesis and anti-HIV activity of isonucleosides and acyclic nucleotides related to clitocine 128
Structure-activity relationships of tiazofurin analogs: synthesis and computational studies of 4'-thio derivatives of thiophenfurin and furanfurin 125
Ribose-modified mizoribine analogues: synthesis and biological evaluation 124
A new tiazofurin pronucleotide: synthesis and biological evaluation of CycloSaligenyl-tiazofurin monophosphate 122
5’-Carbamoyl Derivatives of 2'-C-Methyl-purine Nucleosides as Selective A1 Adenosine Receptor Agonists: Affinity, Efficacy and Selectivity for A1 Receptor from Different Species. 122
2’-C-Methyl derivatives of tecadenoson and 2-chloro-tecadenoson with increased selectivity for human A1 adenosine receptor 121
Synthesis and antiviral evaluation of 1-deaza-8-aza- and 3-deaza-8-aza-purine nucleosides 121
Synthesis, structure, and antiproliferative activity of selenophenfurin, an IMP dehydrogenase inhibitor analogue of selenazofurin. 117
A new acyclic heterodinucleotide active against Human Immunodeficiency Virus and Herpes Simplex Virus 116
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir 116
Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues 112
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus 112
5'-CHLORO-5'-DEOXY-N6-(±)-endo-NORBORNYLADENOSINE, A POTENT AND HIGHLY SELECTIVE HUMAN A1 ADENOSINE RECEPTOR AGONIST, PREVENTS HYPERALGESIA/ALLODYNIA AND EARLY OVER-EXPRESSION OF PRO-APOPTOTIC AND PRO-INFLAMMATORY GENES IN A MICE MODEL OF NEUROPATHIC PAIN 111
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of IsoddA and their phosphates as prodrugs. 111
C-Glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. 109
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics 109
Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogues. Synthesis, Structure, Antitumor Activity and Interactions with IMP Dehydrogenase 107
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands 107
SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF NOVEL HYDRAZONE DERIVATIVES 105
8-Aza derivatives of 3-deazapurine nucleosides. Synthesis and in vitro evaluation of antiviral and antitumor activity 104
Tiazofurin analogs as selective agonists of A1 adenosine receptors 103
Synthesis of 3-deazaclitocine [2-amino-3-nitro-4-(beta-D-ribofuranosylamino)pyridine] as cytotoxic agent 103
Antitumor effects of novel co-drugs linking histone deacetylase and ribonucleotide reductase inhibitors in hematological tumors 101
8-Aza-analogues of PMEA and PMEG: synthesis and in vitro anti-HIV activity. 98
ATP-mimetics derived from 2 '(3 ')-C-methyladenosine as human P2Y2 agonists 97
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin 96
Novel hydrazone derivatives having potent antitumor activity toward multi-drug resistant tumor cells 95
Adenosine receptors as promising targets for the management of ocular diseases 95
C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Deydrogenase Inhibitors 94
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: towards a rational approach of intracellular delivery of nucleoside 5'-monophosphates 94
Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA 94
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY 92
Inhibition of human immunodeficency virus replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine. 92
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N-6-substituted 3'-C-methyladenosine derivatives 89
2'-C-Methyl-2-chloro-N6-cyclopentyladenosine, a potent and highly selective A1 adenosine receptor agonist, has antinociceptive activity and modulates RVM on-and-off cell activities 86
Structure-affinity relathionships of 5'-carbamoyl- and 5'-thionocarbamoyl derivatives of the A1 selective adenosine receptor agonist 2'-MeCCPA as partial A1 agonists 86
2'-C-Methyl analogs of selective adenosine receptors agonists: synthesis and binding studies 85
HISTONE DEACETYLASE (HDAC) INHIBITION MODULATES INTRACELLULAR DEOXYNUCLEOTIDES (DNTP) POOLS AND POTENTIATES THE ANTITUMOR EFFECTS OF THE RIBONUCLEOTIDE REDUCTASE (RR) INHIBITOR 3’- METHYL-ADENOSINE (3’-ME-ADO) IN PROMYELOCITIC LEUKAEMIA CELL LINES. 85
5'-Chloro-5'-deoxy-N6-(±)-endo-norbornyladenosine, a potent and highly selective human A1 adenosine receptor agonist modulates neuropathic pain in mice. 83
Affinity and selectivity of tecadenoson, 2-chloro-tecadenoson and 2’-C-methyl analogues at bovine and pig A1 adenosine receptor 82
C-Nucleoside Analogues of Furanfurin as Ligands to A(1) Adenosine Receptors 82
Selective targeting to macrophages of a new homodinucleotide active aginst human immunodeficiency virus and herpes simplex virus 79
EFFECTS OF METAL(III) COORDINATION ON BIOLOGICAL ACTIVITY OF 2,2'-BIPYRIDYL-6-CARBOTHIOAMIDE (BPYTA), A POTENT R2 RIBONUCLEOTIDE REDUCTASE INHIBITOR 79
A new C-Nucleoside Analogue of Tiazofurin: Synthesis and Biological Evaluation of 2-beta-D-Ribofuranosylimidazole-4-carboxamide (Imidazofurin) 77
IMP Dehydrogenase as a target of antitumor and antiviral chemotherapy 77
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands 76
C-Nucleosides analogues of oxazofurin as selective agonists for adenosine A1 receptors 74
3’-C-Methyl-ribosyl nucleosides as cytotoxic compounds 74
Effects of the selective adenosine A1 receptor agonist 5 '-chloro-5 '-deoxy-N6-(2-endo-norbornyl) adenosine on nociception in mice 70
Effects of 5'-chloro-5'-deoxy-N6-(±)-endo-norbornyl-adenosine, a potent and highly selective A1 adenosine receptor agonist, on neuropathic pain-induced behavioural and morphological changes in spinal microglia 68
New N6-substituted adenosine and 3’-C-methyl-adenosine derivatives as antitumor agents 67
Synthesis and in vivo antiviral activity of 8-aza-analogues of potent antiviral agents 9-[2-phosphonomethoxy)ethyl]adenine (PMEA) and 9-[2-phosphonomethoxy)ethyl]guanine (PMEG) 66
Dual-target dimeric molecules with antitumor properties. Synthesis and biological activity of 3’-C-methyladenosine-valproates 62
Tiazofurine ICN Pharmaceuticals 60
Totale 8.877
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Categoria #
all - tutte 30.746
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.746
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019428 0 0 0 0 0 0 0 0 0 0 184 244
2019/20201.892 255 70 203 382 96 174 152 183 123 109 34 111
2020/20211.285 33 106 56 102 75 74 148 21 116 32 352 170
2021/2022911 69 221 13 65 50 52 22 61 67 88 98 105
2022/20231.172 134 32 66 157 122 164 2 98 222 58 79 38
2023/2024601 122 45 66 18 49 124 25 27 85 40 0 0
Totale 8.877