My doctoral work developed along three directions with different objectives relating to three different research areas: (1) the first part of this doctoral thesis is related to the work carried out in collaboration with the HP Composites company of Ascoli Piceno, Marche, Italy, and concerns studies aimed at developing a method to customize the alkaline treatment of flax and hemp fibers for use in the production of composite epoxy resins for automotive applications. (2) the second part of the doctoral thesis concerns the design, synthesis and characterization of new ruthenium(II) organometallic complexes with pyrazolone and acylpyrazolone ligands containing a pyridine ring and the study of their cytotoxicity against human ovarian cancer (A2780 and Cisplatin - A2780cis resistant) and non-tumor human embryonic kidney cell lines (HEK293T). (3) finally, the third part of the thesis reports the synthesis and characterization of some silver(I) coordination polymers with ditopic bipyrazole ligands and the study of their potential use as chemosensors for the detection of volatile organic compounds (VOCs) released by fruits climacteric after harvest.

Investigation of different materials with applications as Reinforces of Composites, as VOCs Sensors, and as Antitumor Agents

PIETRACCI, LORENZO
2024-04-12

Abstract

My doctoral work developed along three directions with different objectives relating to three different research areas: (1) the first part of this doctoral thesis is related to the work carried out in collaboration with the HP Composites company of Ascoli Piceno, Marche, Italy, and concerns studies aimed at developing a method to customize the alkaline treatment of flax and hemp fibers for use in the production of composite epoxy resins for automotive applications. (2) the second part of the doctoral thesis concerns the design, synthesis and characterization of new ruthenium(II) organometallic complexes with pyrazolone and acylpyrazolone ligands containing a pyridine ring and the study of their cytotoxicity against human ovarian cancer (A2780 and Cisplatin - A2780cis resistant) and non-tumor human embryonic kidney cell lines (HEK293T). (3) finally, the third part of the thesis reports the synthesis and characterization of some silver(I) coordination polymers with ditopic bipyrazole ligands and the study of their potential use as chemosensors for the detection of volatile organic compounds (VOCs) released by fruits climacteric after harvest.
12-apr-2024
Chemical and Pharmaceutical Sciences and Biotechnology
Settore CHIM/03 - Chimica Generale e Inorganica
Settore CHEM-03/A - Chimica generale e inorganica
MARCHETTI, Fabio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/487327
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