The beta-anomers of N-ribofuranosylnicotine-3-carboxamide (beta-NAR) and its nicotinic acid analog (beta-NaR) were obtained by stereoselective synthesis via glycosylation of the presilylated bases under Vorbruggen's protocol. A NAR analog, methylated in position 3 of the ribosylic moiety, is also reported.
Stereoselective synthesis of nicotinamide β-riboside and nucleoside analogs
FRANCHETTI, Palmarisa;PETRELLI, Riccardo;RICCIUTELLI, Massimo;VITA, PATRIZIA;CAPPELLACCI, Loredana
2004-01-01
Abstract
The beta-anomers of N-ribofuranosylnicotine-3-carboxamide (beta-NAR) and its nicotinic acid analog (beta-NaR) were obtained by stereoselective synthesis via glycosylation of the presilylated bases under Vorbruggen's protocol. A NAR analog, methylated in position 3 of the ribosylic moiety, is also reported.File in questo prodotto:
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