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EnglishMaedi Visna is a chronic contagious infectious disease of small ruminants caused by Maedi Visna Virus (MVV), and characterised by lymphoproliferative inflammation in lung and udder. T regulatory cells (TReg), including CD4+CD25+ cells, have been recently demonstrated to be involved in immunomodulation of chronic disease. In order to contribute to the present knowledgements, a preliminary immunohistochemical study was performed to detect the CD25 antigen in pulmonary and mammary sections of sheep experimentally infected with MVV and necropsied after three years. The number of CD4CD25+ cells could be correlated with the type of the lymphoproliferative lesions.
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| Titolo: | CD4+CD25+ T cells in Maedi Visna infection: preliminary immunohistochemical study in experimentally infected sheep. | |
| Autori: | ||
| Data di pubblicazione: | 2007 | |
| Rivista: | ||
| Abstract: | Maedi Visna is a chronic contagious infectious disease of small ruminants caused by Maedi Visna Virus (MVV), and characterised by lymphoproliferative inflammation in lung and udder. T regulatory cells (TReg), including CD4+CD25+ cells, have been recently demonstrated to be involved in immunomodulation of chronic disease. In order to contribute to the present knowledgements, a preliminary immunohistochemical study was performed to detect the CD25 antigen in pulmonary and mammary sections of sheep experimentally infected with MVV and necropsied after three years. The number of CD4CD25+ cells could be correlated with the type of the lymphoproliferative lesions. | |
| Handle: | http://hdl.handle.net/11581/114381 | |
| Appare nelle tipologie: | Articolo |
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