Cerebellar cortical degeneration in ‘Cirneco dell'Etna’ dog: First case report

A 4-month-old, intact male, Cirneco dell’Etna dog was presented with clinical signs of cerebellar ataxia, hindlimb hypometry and short steps with rapid progression. No findings were obtained from blood examinations, magnetic resonance imaging and LCR examinations and the dog was euthanased when it was not able to walk. Histological examination and immunohistochemical staining of the cerebellum showed multifocal depletion of Purkinje cells, marked increase in cellularity (astrogliosis) and a moderate reduction of the cells of the granule layer and thinning of the molecular layer. This case report describes the first case of cerebellar cortical degeneration in a purebreed Cirneco dell’Etna dog