New insights on resveratrol supported by magnesium dihydroxide (Revifast®)

Based on low solubility in water and high membrane permeability, resveratrol is collocated in the second class of the Biopharmaceutical Classification System, with limited absorption derived from a low dissolution rate. Solid microdis-persion of resveratrol supported by magnesium dihydroxide (Resv@MDH, trademark Revifast®) represents a physical mixture of resveratrol (30% w/w) and magnesium dihydroxide (70% w/w) obtained by traditional techniques, such as mixing and micronization under appropriate conditions. Establishing the wide use of Revifast® in food supplements, in the present work we deepen its physicochemical characterization by using diffractometric and infrared analy-sis. No novel species are found in the Resv@MDH mixture except magnesium dihydroxide and resveratrol extracted from Polygonum cuspidatum. The results herein reported strengthened the safety of Revifast® ingredients for resvera-trol-based food supplements