A new one-pot preparation of 3,6-disubstituted pyridazines starting from β-nitro-β,γ-unsaturated ketones and hydrazine monohydrate is presented. The protocol entails two sequential steps, leading to the isolation of the title targets in satisfactory overall yields tolerating a good variety of additional functionalities.

A New One-Pot Synthesis of 3,6-Disubstituted Pyridazines Starting from β-Nitro-β,γ-Unsaturated Ketones

Marino Petrini 
Penultimo
;
Alessandro Palmieri
Ultimo
2023-01-01

Abstract

A new one-pot preparation of 3,6-disubstituted pyridazines starting from β-nitro-β,γ-unsaturated ketones and hydrazine monohydrate is presented. The protocol entails two sequential steps, leading to the isolation of the title targets in satisfactory overall yields tolerating a good variety of additional functionalities.
2023
262
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/478563
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