Flow chemical synthesis has been fruitfully used for synthesizing cannabidiol (CBD) and its analogues cannabidivarin (CBDV) and cannabidibutol (CBDB) in 55 %, 56 %, and 59 % yields respectively. This approach permitted both to synthesize products in very short reaction time (residence time 7 minutes) and minimized the formation of psychoactive and illegal cannabinoids such a tetrahydrocannabinol (THC).
A Novel and Practical Continuous Flow Chemical Synthesis of Cannabidiol (CBD) and its CBDV and CBDB Analogues
Elena ChiurchiùPrimo
;Roberto BalliniPenultimo
;Alessandro Palmieri
Ultimo
2021-01-01
Abstract
Flow chemical synthesis has been fruitfully used for synthesizing cannabidiol (CBD) and its analogues cannabidivarin (CBDV) and cannabidibutol (CBDB) in 55 %, 56 %, and 59 % yields respectively. This approach permitted both to synthesize products in very short reaction time (residence time 7 minutes) and minimized the formation of psychoactive and illegal cannabinoids such a tetrahydrocannabinol (THC).File in questo prodotto:
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Eur. J. Org. Chem. 2021, 1286-1289.pdf
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Descrizione: Eur. J. Org. Chem. 2021, 1286-1289
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