Canine fiber responsive diarrhea is a form of chronic colitis that improves clinically after adding fiber to the diet. In the present study, we investigated the effect of a combination of a high fiber, highly digestible, hypoallergenic diet with a probiotic mixture in 30 dogs with chronic colitis that was unresponsive to various dietary and/or pharmacological interventions. Fecal scores, CCECAI scores, dysbiosis index (DI), and histologic images of colonic biopsies were evaluated. At baseline (day 0; T0) and after 30 days of treatment (T1). All variables evaluated in our patients (i.e., fecal and CCECAI scores and histopathology) improved significantly at T1, with the exception of DI. However, there was a numerical shift from a state of dysbiosis to one of normobiosis. The combination of diet and probiotic used in the present study induced resolution of clinical signs in a mean of 8.5 days (maximum 15 days), and did not necessitate any other treatments or further addition of alimentary fiber

Rapid Resolution of Large Bowel Diarrhea After the Administration of a Combination of a High-Fiber Diet and a Probiotic Mixture in 30 Dogs

Rossi, Giacomo;Cerquetella, Matteo;Gavazza, Alessandra;Galosi, Livio;Berardi, Sara;Mangiaterra, Sara;Mari, Subeide;
2020-01-01

Abstract

Canine fiber responsive diarrhea is a form of chronic colitis that improves clinically after adding fiber to the diet. In the present study, we investigated the effect of a combination of a high fiber, highly digestible, hypoallergenic diet with a probiotic mixture in 30 dogs with chronic colitis that was unresponsive to various dietary and/or pharmacological interventions. Fecal scores, CCECAI scores, dysbiosis index (DI), and histologic images of colonic biopsies were evaluated. At baseline (day 0; T0) and after 30 days of treatment (T1). All variables evaluated in our patients (i.e., fecal and CCECAI scores and histopathology) improved significantly at T1, with the exception of DI. However, there was a numerical shift from a state of dysbiosis to one of normobiosis. The combination of diet and probiotic used in the present study induced resolution of clinical signs in a mean of 8.5 days (maximum 15 days), and did not necessitate any other treatments or further addition of alimentary fiber
2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/432674
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