Half sandwich organometal complexes of Ru(II), Os(II), Rh(III) and Ir(III) with -diketone-like ligands have been extensively explored in the last years as potential prodrugs in anticancer therapy. Herein a mini review of this class of compounds is provided. A discussion of the basic structural features of the metal complexes is given together with their in vitro anticancer activity.
Half sandwich metal complexes with β-diketone-like ligands and their anticancer activity
Pettinari, Riccardo;Marchetti, Fabio;Di Nicola, Corrado;Pettinari, Claudio
2018-01-01
Abstract
Half sandwich organometal complexes of Ru(II), Os(II), Rh(III) and Ir(III) with -diketone-like ligands have been extensively explored in the last years as potential prodrugs in anticancer therapy. Herein a mini review of this class of compounds is provided. A discussion of the basic structural features of the metal complexes is given together with their in vitro anticancer activity.File in questo prodotto:
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