Dimethyl maleate was found to be a very reactive and selective acceptor for the aza-Michael addition in comparison to other commonly used electron-deficient alkenes. It reacts efficiently with a variety of aliphatic amines in complete absence of any catalyst and solvent at room temperature. Under these environmentally-friendly conditions, high yields of selectively mono-adducts were obtained within short reaction times.
Uncatalyzed, green aza-Michael addition of amines to dimethyl maleate
BOSICA, Giovanna;
2014-01-01
Abstract
Dimethyl maleate was found to be a very reactive and selective acceptor for the aza-Michael addition in comparison to other commonly used electron-deficient alkenes. It reacts efficiently with a variety of aliphatic amines in complete absence of any catalyst and solvent at room temperature. Under these environmentally-friendly conditions, high yields of selectively mono-adducts were obtained within short reaction times.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
