Reaction of alpha-amido sulfones with nitro ketals promoted by KF on alumina provides the corresponding adducts which, upon treatment with p-toluenesulfonic acid, generate the corresponding N-alkoxycarbonyl-2,5-disubstituted pyrroles. The latter transformation involves a cascade process including ketal cleavage, ring closure and final aromatization by nitrous acid elimination.
Reaction of alpha-amido sulfones with functionalized nitrocompounds: a new two-step synthesis of Nalkoxycarbonyl-2,5-disubstituted pyrroles
BALLINI, Roberto;GABRIELLI, Serena;PALMIERI, Alessandro;PETRINI, Marino
2014-01-01
Abstract
Reaction of alpha-amido sulfones with nitro ketals promoted by KF on alumina provides the corresponding adducts which, upon treatment with p-toluenesulfonic acid, generate the corresponding N-alkoxycarbonyl-2,5-disubstituted pyrroles. The latter transformation involves a cascade process including ketal cleavage, ring closure and final aromatization by nitrous acid elimination.File in questo prodotto:
File | Dimensione | Formato | |
---|---|---|---|
RSCA14,43258.pdf
accesso aperto
Tipologia:
Versione Editoriale
Licenza:
PUBBLICO - Creative Commons
Dimensione
216.91 kB
Formato
Adobe PDF
|
216.91 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.