A GRID-based multilayer architecture for bioinformatics

The volume and complexity of biological data and informations available today need a significant computational data and processes analysis. A huge amount of bioinformatics databases and tools is available. Some of them allow bioinformaticians to intuitively compose their in-silico experiments in the form of workflows. Other applications aim at the analysis, modeling and simulation of biological systems and processes. In this context, the quest for resources becomes a very demanding and time-consuming activity, so that a dynamic semantic indexing system of bioinformatics resources becomes essential. As a consequence, the availability of a virtual desk fulfilling bioinformaticians needs, undoubtedly constitutes an important requirement in modern and future biology. For this purpose, we propose a GRID-based multilayer architecture, intended to support in-silico experiments, resource discovery and biological systems simulation.