Solid dispersions of fenofibrate in PEG 4000 were prepared by the solvent and fusion methods. The binary systems are successively studied and characterized using differential scanning calorimetry. X-ray diffractometry and Fourie transform infrared spectroscopy. Dissolution studies of the solid dispersed powders were performed to verify the water solubility improvement of the fenofibrate present in the formulations.
Characterization and dissolution studies of PEG 4000/fenofibrate solid dispersions
PALMIERI, Giovanni Filippo;
1996-01-01
Abstract
Solid dispersions of fenofibrate in PEG 4000 were prepared by the solvent and fusion methods. The binary systems are successively studied and characterized using differential scanning calorimetry. X-ray diffractometry and Fourie transform infrared spectroscopy. Dissolution studies of the solid dispersed powders were performed to verify the water solubility improvement of the fenofibrate present in the formulations.File in questo prodotto:
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