Consideration on the lipid profile of a sample of the population of the Marche region and on the relationship (Tot. Col. + Triglyc. Col. HDL)/Col. HDL as atherogenic risk indices

The authors studied the lipid profile of 1.635 patients of both sexes by means of the dosage ofplasma lipids, their distribution according to age and sex, and the calculation of known ratios which are considered risk indices for atherosclerosis. A new risk index has been proposed which includes, apart from the previously used parameters, also triglyceridemiae. Correlation tests have been carried out. In the sample studied about 38% have a lipid parameter above the norm and the risk factor indices identify different situations, from the mildest which concem the increase of a single parameter to more substantial changes involving variations of several parameters. The incidence of the triglyceride blood level (which was above overage in 27% of the cases) was emphasized when assessing atherogenic risk and also its connection with the inverse correlation with cholesterol - HDL. The sample tested showed, in about 25% of the cases, an above overage risk and at the same time cholesterol- HDL below the norm in both sexes. Whilst reiterating that elettrophoresis of plasma lipids does not always give rise to a clear and reliable interpretation, the authors suggest that comprehensive haemato-chemical data (total cholesterol, LDL and HDL fractions, triglycerides) and the indices which are derived from them can be an effective method in assessing atherogenic risk.