Nitrocyclopropane formation has been successfully carried out by reaction of bromonitromethane with electrophilic alkenes bearing two electron-withdrawing groups in the α- and β-positions, and in the presence of potassium carbonate as base. The method allows good yields and moderate to satisfactory diastereoselectivity with linear alkenes, while shows the complete formation of the exo-product with N-alkylmaleimides.

A General Procedure for the One-pot Preparation of Polyfunctionalized Nitrocyclopropanes

BALLINI, Roberto;FIORINI, Dennis;PALMIERI, Alessandro
2003-01-01

Abstract

Nitrocyclopropane formation has been successfully carried out by reaction of bromonitromethane with electrophilic alkenes bearing two electron-withdrawing groups in the α- and β-positions, and in the presence of potassium carbonate as base. The method allows good yields and moderate to satisfactory diastereoselectivity with linear alkenes, while shows the complete formation of the exo-product with N-alkylmaleimides.
2003
262
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/242131
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