The participation of POMC-derived peptides in the control of reproductive function is not clear; however, evidence indicate that in mammals the opioid peptide beta-endorphin (beta-EP), has a physiological role in regulating pituitary hormone secretion, including gonadotropins. To investigate this aspect, we assessed whether beta-EP binding sites would be present in pars distalis, and the wild population of anuran Rana esculenta was considered a good model; therefore, beta-EP specific binding sites were visualized by confocal laser scanning microscopy in primary cell culture.

beta-endorphin binding sites in pars distalis of the frog, Rana esculenta

SABBIETI, Maria Giovanna;MARCHETTI, Luigi;
1996

Abstract

The participation of POMC-derived peptides in the control of reproductive function is not clear; however, evidence indicate that in mammals the opioid peptide beta-endorphin (beta-EP), has a physiological role in regulating pituitary hormone secretion, including gonadotropins. To investigate this aspect, we assessed whether beta-EP binding sites would be present in pars distalis, and the wild population of anuran Rana esculenta was considered a good model; therefore, beta-EP specific binding sites were visualized by confocal laser scanning microscopy in primary cell culture.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11581/242125
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