We report the ex vivo lysogenic transfer of erythromycin and tetracycline resistance genes among group A streptococci (GAS). Of 42 susceptible strains, 69% acquired erythromycin/tetracycline resistance when infected with purified supernatants from strain m46 culture containing the phage Φm46.1. A significant emm-type-dependent barrier to lysogenic transfer was not observed. The emm12 strains were the only strains susceptible to the lytic action of the bacteriophage preparation.

Lysogenic transfer of mef(A) and tet(O) genes carried by Phim46.1 among group A streptococci.

DI LUCA, MARIA CHIARA;PETRELLI, Dezemona;PRENNA, Manuela;RIPA, Sandro;VITALI, Luca Agostino
2010-01-01

Abstract

We report the ex vivo lysogenic transfer of erythromycin and tetracycline resistance genes among group A streptococci (GAS). Of 42 susceptible strains, 69% acquired erythromycin/tetracycline resistance when infected with purified supernatants from strain m46 culture containing the phage Φm46.1. A significant emm-type-dependent barrier to lysogenic transfer was not observed. The emm12 strains were the only strains susceptible to the lytic action of the bacteriophage preparation.
2010
262
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/202793
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