Elimination of suitable leaving groups from 3-substituted indoles under basic or acidic conditions readily provides alkylideneindolenine intermediates that may react with a large variety of nucleophilic reagents. This article highlights some recent developments of this synthetic approach for the preparation of functionalized indole derivatives.
Synthesis of 3-substituted indoles via reactive alylideneindolenine intermediates
PALMIERI, Alessandro;PETRINI, Marino;SHAIKH, RAFIK RAJJAK
2010-01-01
Abstract
Elimination of suitable leaving groups from 3-substituted indoles under basic or acidic conditions readily provides alkylideneindolenine intermediates that may react with a large variety of nucleophilic reagents. This article highlights some recent developments of this synthetic approach for the preparation of functionalized indole derivatives.File in questo prodotto:
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