A versatile and chemoselective route to exo-methylene butyrolactones was developed by employing a three step reaction sequence consisting of Michael addition of primary nitroalkanes to ethyl (2-bromomethyl)acrylate, then Nef conversion of the nitro derivatives and subsequent lactonization of the obtaines keto esters.

A New Synthesis of exo-Methylene Butyrolactones from Nitroalkanes

BALLINI, Roberto;BOSICA, Giovanna;
2001-01-01

Abstract

A versatile and chemoselective route to exo-methylene butyrolactones was developed by employing a three step reaction sequence consisting of Michael addition of primary nitroalkanes to ethyl (2-bromomethyl)acrylate, then Nef conversion of the nitro derivatives and subsequent lactonization of the obtaines keto esters.
2001
262
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/114584
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact