A new oleanane-type triterpene saponin, b-D-glucopyranosyl 2a,3b,6b-trihydroxy-23-galloylolean-12-en-28-oate (1), together with four known oleanane-type pentacyclic triterpenoids, combregenin (2), arjungenin (3), arjunglucoside I (4), and combreglucoside (5) were isolated from the stem bark of Combretum molle. Their structures were established mainly on the basis of 1D and 2D NMR spectral data. Compounds 1–3 exhibited more significant activity against carrageenan-induced paw edema in rat compared to compounds 4 and 5
Polyhydroxyoleanane-type triterpenoids from Combretum molle and their anti-inflammatory activity
BARBONI, Luciano;
2008-01-01
Abstract
A new oleanane-type triterpene saponin, b-D-glucopyranosyl 2a,3b,6b-trihydroxy-23-galloylolean-12-en-28-oate (1), together with four known oleanane-type pentacyclic triterpenoids, combregenin (2), arjungenin (3), arjunglucoside I (4), and combreglucoside (5) were isolated from the stem bark of Combretum molle. Their structures were established mainly on the basis of 1D and 2D NMR spectral data. Compounds 1–3 exhibited more significant activity against carrageenan-induced paw edema in rat compared to compounds 4 and 5File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
