A simple procedure for the preparation of 3-(1-arylsulfonyl-alkyl) indoles by three-component condensation of indoles, carbonyls, and arenesulfinic acids is presented. The obtained products undergo a Reformatsky reaction leading to alkyl 3-(3-indolyl) alkanoates and (3-indolyl) ketones.

A Simplified Synthesis of 3-(1-Arylsulfonylalkyl) Indoles and their Reaction with Reformatsky Reagents

PALMIERI, Alessandro;PETRINI, Marino
2007-01-01

Abstract

A simple procedure for the preparation of 3-(1-arylsulfonyl-alkyl) indoles by three-component condensation of indoles, carbonyls, and arenesulfinic acids is presented. The obtained products undergo a Reformatsky reaction leading to alkyl 3-(3-indolyl) alkanoates and (3-indolyl) ketones.
2007
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/102667
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