Molecules: Metal-Based Drugs

Metals have been considered for millennia to have medicinal values, and with the advent of modern medicine, numerous metal-based drugs have proven to be highly effective in clinical settings. Many different metal ions have shown activity against a range of diseases, beyond their well-known applications in cancer (cisplatin) or rheumatoid arthritis (auranofin). The widespread medicinal applications of metal-based compounds have captured the attention of the scientific community in recent years for the variety of compounds studied owing to their wide spectrum of reactivity and the width of their applications in medicinal chemistry for the synthesis of chemotherapeutic and diagnostic molecules not readily accessible to organic compounds. This Special Issue will cover a selection of recent research and review articles to collect and disseminate some of the most significant and recent contributions in the field of metals used in medicine, highlighting their pharmacological applications in several diseases, such as cancers, diabetes, osteoporosis, and as diagnostic agents.