Ziziphus mucronata (rhamnaceae), known in South Africa as the "buffalo thorn", is reported to have numerous magico-medicinal uses. Pharmacological investigations have shown sedative, analgesic, anti-inflammatory and antibacterial activities. The alkaloid extract of the roots afforded as main component the already known cyclopeptide alkaloid mucronine-D. Among the minor compounds O-demethyl mucronine-D, and a new cyclopeptide alkaloid, which is an isomer of sativanine-K, were isolated. The structure of the three compounds have been mainly determined through recent 1D- (selective excitation) and 2D-NMR (long-range C-H correlation and ROESY).
New cyclopeptide alkaloids from Ziziphus mucronata
BARBONI, Luciano;GARIBOLDI, Pierluigi Vittorio;TORREGIANI, Elisabetta
1993-01-01
Abstract
Ziziphus mucronata (rhamnaceae), known in South Africa as the "buffalo thorn", is reported to have numerous magico-medicinal uses. Pharmacological investigations have shown sedative, analgesic, anti-inflammatory and antibacterial activities. The alkaloid extract of the roots afforded as main component the already known cyclopeptide alkaloid mucronine-D. Among the minor compounds O-demethyl mucronine-D, and a new cyclopeptide alkaloid, which is an isomer of sativanine-K, were isolated. The structure of the three compounds have been mainly determined through recent 1D- (selective excitation) and 2D-NMR (long-range C-H correlation and ROESY).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
