The organometallic chemistry of half-sandwich η6-arene-ruthenium(II) complexes has been widely developed in the last few years, due to their wide range of potential applications as catalysts, as well as for their potent antibacterial and anticancer activity. As an extension of our previous work on the coordination chemistry of ruthenium arene fragments with 4-acyl-5-pyrazolone and b-ketoamine ligands, here we report the synthesis and full characterization (IR, 1H NMR, 13C NMR, ESI-MS, Elem. Anal. and X-ray diffraction studies) of novel η6-arene RuII complexes (arene = benzene, p-cymene or examethylbenzene) containing new hydrazone ligands with general structure HL’. Preliminary results on their biological activity will be reported.
New Half-Sandwich Ruthenium(II) Complexes bearing Hydrazone Ligands: Organometallic Chemistry and Bioactivity
ORBISAGLIA, SERENA;CONDELLO, FRANCESCA;PALMUCCI, JESSICA;PETRINI, Agnese;PETRELLI, Riccardo;CAPPELLACCI, Loredana;LUPIDI, Giulio;PETTINARI, Riccardo;MARCHETTI, Fabio;PETTINARI, Claudio
2014-01-01
Abstract
The organometallic chemistry of half-sandwich η6-arene-ruthenium(II) complexes has been widely developed in the last few years, due to their wide range of potential applications as catalysts, as well as for their potent antibacterial and anticancer activity. As an extension of our previous work on the coordination chemistry of ruthenium arene fragments with 4-acyl-5-pyrazolone and b-ketoamine ligands, here we report the synthesis and full characterization (IR, 1H NMR, 13C NMR, ESI-MS, Elem. Anal. and X-ray diffraction studies) of novel η6-arene RuII complexes (arene = benzene, p-cymene or examethylbenzene) containing new hydrazone ligands with general structure HL’. Preliminary results on their biological activity will be reported.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
