Mesenchymal stem cells (MSCs) were maintained at different temperatures for different time periods to simulate the phase of transport before their clinical use. Subsequently, MSCs were subjected to the following trials: cell viability, duplication time, Colony-Forming Unit Assay, adipogenic and osteogenic differentiation, immunophenotype, karyotype evaluation. The obtained results seem to suggest that the tested maintenance conditions are unable to induce appeciable modifications on MSCs behaviour and that the ceels can be considered safe for clinical applications.

Differenti condizioni di trasporto non alterano le caratteristiche di cellule staminali mesenchimali destinate ad impiego clinico

SCOCCO, Paola;
2011-01-01

Abstract

Mesenchymal stem cells (MSCs) were maintained at different temperatures for different time periods to simulate the phase of transport before their clinical use. Subsequently, MSCs were subjected to the following trials: cell viability, duplication time, Colony-Forming Unit Assay, adipogenic and osteogenic differentiation, immunophenotype, karyotype evaluation. The obtained results seem to suggest that the tested maintenance conditions are unable to induce appeciable modifications on MSCs behaviour and that the ceels can be considered safe for clinical applications.
2011
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/241531
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