Enacting Proactive Workflows Engine in e-Science

The dynamic nature and the geographic distribution of scientific resources, require flexible and adaptive computational envi- ronment where an in-silico experiment can be executed as a workflow of activities. In this paper, we propose a software environment to dy- namically generate domain-specific, agent-based workflow engines from workflow specifications. The workflow engine is a proactive multiagent system -a distributed, concurrent system- whose autonomous compo- nents interact in performing the workflow activities in a specific domain. The proposed approach has been implemented on Hermes, agent-based mobile computing middleware, and tested within “Oncology over Inter- net” project.