Ziziphus mucronata (rhamnaceae), known in South Africa as the "buffalo thorn", is reported to have numerous magico-medicinal uses. Pharmacological investigations have shown sedative, analgesic, anti-inflammatory and antibacterial activities. The alkaloid extract of the roots afforded as main component the already known cyclopeptide alkaloid mucronine-D. Among the minor compounds O-demethyl mucronine-D, and a new cyclopeptide alkaloid, which is an isomer of sativanine-K, were isolated. The structure of the three compounds have been mainly determined through recent 1D- (selective excitation) and 2D-NMR (long-range C-H correlation and ROESY).

New cyclopeptide alkaloids from Ziziphus mucronata

BARBONI, Luciano;GARIBOLDI, Pierluigi Vittorio;TORREGIANI, Elisabetta
1993-01-01

Abstract

Ziziphus mucronata (rhamnaceae), known in South Africa as the "buffalo thorn", is reported to have numerous magico-medicinal uses. Pharmacological investigations have shown sedative, analgesic, anti-inflammatory and antibacterial activities. The alkaloid extract of the roots afforded as main component the already known cyclopeptide alkaloid mucronine-D. Among the minor compounds O-demethyl mucronine-D, and a new cyclopeptide alkaloid, which is an isomer of sativanine-K, were isolated. The structure of the three compounds have been mainly determined through recent 1D- (selective excitation) and 2D-NMR (long-range C-H correlation and ROESY).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11581/367391
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