Substituted piperazines are important heterocycles possessing wide and important biological activities. Herein we report a new easy synthetic approach for preparation of alkyl 3- substituted 5-oxopiperazine-2-carboxylates using b-nitroacrylates as key starting materials.
β-Nitroacrylates as key building blocks for the synthesis of alkyl 3-substituted 5- oxopiperazine-2-carboxylates under fully heterogeneous conditions.
GABRIELLI, Serena;BALLINI, Roberto;PALMIERI, Alessandro
2013-01-01
Abstract
Substituted piperazines are important heterocycles possessing wide and important biological activities. Herein we report a new easy synthetic approach for preparation of alkyl 3- substituted 5-oxopiperazine-2-carboxylates using b-nitroacrylates as key starting materials.File in questo prodotto:
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