This article describes a new, convenient, improved synthesis of the 2-debenzoyl-2-m-methoxybenzoyl-7-triethylsilyl-13-oxo-14p-hydroxybaccatin III 1,14-carbonate, the key intermediate in the synthesis of two new second-generation antitumor taxanes
14Beta-Hydroxy-10-deacetylbaccatin III as a Convenient, Alternative Substrate for the Improved Synthesis of Methoxylated Second-Generation Taxanes
BARBONI, Luciano;GIARLO, Guido;BALLINI, Roberto;
2006-01-01
Abstract
This article describes a new, convenient, improved synthesis of the 2-debenzoyl-2-m-methoxybenzoyl-7-triethylsilyl-13-oxo-14p-hydroxybaccatin III 1,14-carbonate, the key intermediate in the synthesis of two new second-generation antitumor taxanesFile in questo prodotto:
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