TORQUATI, ILARIA
TORQUATI, ILARIA
4-acyl-5-pyrazolone-based hydrazones as novel anti-Trypanosoma brucei agents: structural design, synthesis and biological evaluation
2015-01-01 Petrelli, Riccardo; Torquati, Ilaria; Scortichini, Mirko; DI GIOACCHINO, Valentina; Palumbo, Francesca; Bartelucci, Luca; Pettinari, Riccardo; Condello, Francesca; Pettinari, Claudio; Marchetti, Fabio; Hofer, Anders; Ranjbarian, Farahnaz; Cappellacci, Loredana
4’-TETRAZOLYL-ALKYL-N6-SUBSTITUTED ADENOSINE DERIVATIVES AS HIGHLY POTENT DUAL ACTING A1 ADENOSINE RECEPTOR AGONISTS AND A3 ADENOSINE RECEPTOR ANTAGONISTS
2014-01-01 Petrelli, Riccardo; Torquati, Ilaria; Livio, Luongo; Francesca, Guida; Serena, Boccella; Antonio, Lavecchia; Karl Norbert, Klotz; Sonja, Kachler; Palmarisa, Franchetti; Mario, Grifantini; Sabatino, Maione; Cappellacci, Loredana
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY
2013-01-01 Petrelli, Riccardo; Torquati, Ilaria; Vita, Patrizia; L., Luongo; K. N., Klotz; S., Kachler; F., Guida; M., De Chiaro; S., Maione; Franchetti, Palmarisa; Grifantini, Mario; Cappellacci, Loredana
5’-deoxy-5’-N-pyrazolyl-N6-substituded adenosine derivates as A1 adenosine receptor agonists: synthesis and antinociception in mice
2015-01-01 Petrelli, Riccardo; Torquati, Ilaria; Livio, Luongo; Sonja, Kachler; Vita, Patrizia; Scortichini, Mirko; Antonio, Lavecchia; Sabatino, Maione; Karl Nornert, Klotz; Cappellacci, Loredana
5′-C-Ethyl-tetrazolyl-N6-Substituted Adenosine and 2-Chloro-adenosine Derivatives as Highly Potent Dual Acting A1 Adenosine Receptor Agonists and A3 Adenosine Receptor Antagonists
2015-01-01 Petrelli, Riccardo; Torquati, Ilaria; Sonja, Kachler; Livio, Luongo; Sabatino, Maione; Palmarisa, Franchetti; Mario, Grifantini; Ettore, Novellino; Antonio, Lavecchia; Karl Norbert, Klotz; Cappellacci, Loredana
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands
2012-01-01 Cappellacci, Loredana; Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; Jacobson, Ka; Barrett, Mo; Franklin, D; Harden, Kt; Franchetti, Palmarisa; Grifantini, Mario
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands
2011-01-01 Cappellacci, Loredana; Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; Kenneth A., Jacobson; Matthew, Barrett; T., Kendall Harden; Franchetti, Palmarisa; Grifantini, Mario
Allosteric control in the synthesis and sensing of cyclic-di-GMP
2015-01-01 Fernicola, Silvia; Rinaldo, Serena; Giardina, Giorgio; Brunotti, Paolo; Stelitano, Valentina; Paiardini, Alessandro; Petrelli, Riccardo; Torquati, Ilaria; Cappellacci, Loredana; Cutruzzolà, Francesca
Bisphosphonate Derivatives of 2’-C-Methyl-, and 3’-C-Methyl-Adenosine as Ligands at P2Y1 and P2Y2 Receptors
2012-01-01 Petrelli, Riccardo; Vita, Patrizia; Franchetti, P; Torquati, Ilaria; Barrett, O. M.; Harden, Kt; Grifantini, M; Cappellacci, Loredana
c-di-GMP-based molecules as potent diguanylate cyclase (DGC) inhibitors
2015-01-01 Petrelli, Riccardo; Torquati, Ilaria; Scortichini, Mirko; Rinaldo, Serena; Fernicola, Silvia; Giardina, Giorgio; Paiardini, Alessandro; Leoni, Livia; Rampioni, Giordano; Messina, Marco; Cutruzzolà, Francesca; Cappellacci, Loredana
Design, synthesis and biological evaluation of novel inhibitors of key enzymes in c-di-GMP metabolism as potential antibiofilm drugs
2015-03-20 Torquati, Ilaria
Design, synthesis and biological evaluation of novel inhibitors of NAD kinase
2012-01-01 Torquati, Ilaria; Vita, Patrizia; Petrelli, Riccardo; Di Stefano, M; Cappellacci, Loredana
Design, Synthesis, and Anticancer Activity of Novel Pyridyl and Aryl Hydrazones
2015-01-01 Petrelli, Riccardo; Torquati, Ilaria; Scortichini, Mirko; Grisogani, Federica; Angeloni, Yara; Girotti, Francesca; Brusseel, Marieke; Nabissi, Massimo; Santoni, Giorgio; Hofer, Anders; Ranjbarian, Farahnaz; Cappellacci, Loredana
Exploring the Role of N6‐Substituents in Potent Dual Acting 5'‐C‐Ethyltetrazolyladenosine Derivatives: Synthesis, Binding, Functional Assays, and Antinociceptive Effects in Mice
2017-01-01 Petrelli, Riccardo; Scortichini, Mirko; Kachler, Sonja; Boccella, Serena; Cerchia, Carmen; Torquati, Ilaria; DEL BELLO, Fabio; Salvemini, Daniela; Novellino, Ettore; Luongo, Livio; Maione, Sabatino; A Jacobson, Kenneth; Lavecchia, Antonio; Klotz, Karl-Norbert; Cappellacci, Loredana
From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine
2014-01-01 Petrelli, Riccardo; Maria, Meli; Vita, Patrizia; Torquati, Ilaria; Arianna, Ferro; Munender, Vodnala; Natale, D’Alessandro; Manlio, Tolomeo; DEL BELLO, Fabio; Praveen, Kusumanchi; Palmarisa, Franchetti; Mario, Grifantini; Hiremagalur N., Jayaram; Anders, Hofer; Cappellacci, Loredana
IDENTIFICATION OF MOLECULES THAT INHIBITS c-di-GMP SYNTHESIS TO TARGET BIOFILM FORMATION
2014-01-01 Fernicola, S; Paiardini, A; Rinaldo, S; Torquati, Ilaria; Petrelli, Riccardo; Cappellacci, Loredana; Cutruzzolà, F.
N6/5’-DISUBSTITUTED ADENOSINE AND 2-CHLORO-ADENOSINE DERIVATIVES AS POTENT AND SELECTIVE A1 ADENOSINE RECEPTOR AGONISTS: SYNTHESIS, BINDING ASSAYS AND ANTINOCICEPTIVE ACTIVITY IN MICE
2013-01-01 Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; L., Luongo; F., Guida; M., De Chiaro; K. N., Klotz; S., Kachler; P., Franchetti; S., Maione; M., Grifantini; Cappellacci, Loredana
N6/5’-DISUBSTITUTED ADENOSINE AND 2-CHLORO-ADENOSINE DERIVATIVES AS POTENT AND SELECTIVE A1 ADENOSINE RECEPTOR AGONISTS: SYNTHESIS, BINDING ASSAYS AND ANTINOCICEPTIVE ACTIVITY IN MICE
2014-01-01 Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; Livio, Luongo; Francesca, Guida; Maria De, Chiaro; Karl Norbert, Klotz; Sonja, Kachler; Palmarisa, Franchetti; Sabatino, Maione; Mario, Grifantini; Cappellacci, Loredana
NOVEL 2-SUBSTITUTED 2’/3’-C-METHYL-ADENOSINE DERIVATIVES: SYNTHESIS AND BIOLOGICAL EVALUATION AGAINST TRYPANOSOMA BRUCEI
2013-01-01 Petrelli, Riccardo; Torquati, Ilaria; Vita, Patrizia; L., Boccoli; A., Hofer; M., Vodnala; P., Franchetti; M., Grifantini; Cappellacci, Loredana
Novel dual acting 5’-C-ethyl-tetrazolyl-N6-substituted adenosine derivatives: synthesis and biological evaluation
2015-01-01 Petrelli, Riccardo; Torquati, Ilaria; Livio, Luongo; Sonja, Kachler; Angeloni, Yara; Marieke, Brusseel; Antonio, Lavecchia; Sabatino, Maione; Karl Norbert, Klotz; Cappellacci, Loredana
Titolo | Data di pubblicazione | Autore(i) | Tipo | File |
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4-acyl-5-pyrazolone-based hydrazones as novel anti-Trypanosoma brucei agents: structural design, synthesis and biological evaluation | 1-gen-2015 | Petrelli, Riccardo; Torquati, Ilaria; Scortichini, Mirko; DI GIOACCHINO, Valentina; Palumbo, Francesca; Bartelucci, Luca; Pettinari, Riccardo; Condello, Francesca; Pettinari, Claudio; Marchetti, Fabio; Hofer, Anders; Ranjbarian, Farahnaz; Cappellacci, Loredana | Poster atto convegno su volume | |
4’-TETRAZOLYL-ALKYL-N6-SUBSTITUTED ADENOSINE DERIVATIVES AS HIGHLY POTENT DUAL ACTING A1 ADENOSINE RECEPTOR AGONISTS AND A3 ADENOSINE RECEPTOR ANTAGONISTS | 1-gen-2014 | Petrelli, Riccardo; Torquati, Ilaria; Livio, Luongo; Francesca, Guida; Serena, Boccella; Antonio, Lavecchia; Karl Norbert, Klotz; Sonja, Kachler; Palmarisa, Franchetti; Mario, Grifantini; Sabatino, Maione; Cappellacci, Loredana | Contributo in atto di convegno su rivista | |
5’-CHLORO-5’-DEOXY-N6-SUBSTITUTED ADENOSINE DERIVATIVES: SYNTHESIS, ADENOSINE RECEPTOR AFFINITY AND ANTINOCICEPTIVE ACTIVITY | 1-gen-2013 | Petrelli, Riccardo; Torquati, Ilaria; Vita, Patrizia; L., Luongo; K. N., Klotz; S., Kachler; F., Guida; M., De Chiaro; S., Maione; Franchetti, Palmarisa; Grifantini, Mario; Cappellacci, Loredana | Poster atto convegno su volume | |
5’-deoxy-5’-N-pyrazolyl-N6-substituded adenosine derivates as A1 adenosine receptor agonists: synthesis and antinociception in mice | 1-gen-2015 | Petrelli, Riccardo; Torquati, Ilaria; Livio, Luongo; Sonja, Kachler; Vita, Patrizia; Scortichini, Mirko; Antonio, Lavecchia; Sabatino, Maione; Karl Nornert, Klotz; Cappellacci, Loredana | Poster atto convegno su volume | |
5′-C-Ethyl-tetrazolyl-N6-Substituted Adenosine and 2-Chloro-adenosine Derivatives as Highly Potent Dual Acting A1 Adenosine Receptor Agonists and A3 Adenosine Receptor Antagonists | 1-gen-2015 | Petrelli, Riccardo; Torquati, Ilaria; Sonja, Kachler; Livio, Luongo; Sabatino, Maione; Palmarisa, Franchetti; Mario, Grifantini; Ettore, Novellino; Antonio, Lavecchia; Karl Norbert, Klotz; Cappellacci, Loredana | Articolo | |
ADP- and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands | 1-gen-2012 | Cappellacci, Loredana; Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; Jacobson, Ka; Barrett, Mo; Franklin, D; Harden, Kt; Franchetti, Palmarisa; Grifantini, Mario | Contributo in atto di convegno su rivista | |
ADP-, and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 ligands | 1-gen-2011 | Cappellacci, Loredana; Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; Kenneth A., Jacobson; Matthew, Barrett; T., Kendall Harden; Franchetti, Palmarisa; Grifantini, Mario | Poster atto convegno su volume | |
Allosteric control in the synthesis and sensing of cyclic-di-GMP | 1-gen-2015 | Fernicola, Silvia; Rinaldo, Serena; Giardina, Giorgio; Brunotti, Paolo; Stelitano, Valentina; Paiardini, Alessandro; Petrelli, Riccardo; Torquati, Ilaria; Cappellacci, Loredana; Cutruzzolà, Francesca | Poster atto convegno su volume | |
Bisphosphonate Derivatives of 2’-C-Methyl-, and 3’-C-Methyl-Adenosine as Ligands at P2Y1 and P2Y2 Receptors | 1-gen-2012 | Petrelli, Riccardo; Vita, Patrizia; Franchetti, P; Torquati, Ilaria; Barrett, O. M.; Harden, Kt; Grifantini, M; Cappellacci, Loredana | Poster atto convegno su volume | |
c-di-GMP-based molecules as potent diguanylate cyclase (DGC) inhibitors | 1-gen-2015 | Petrelli, Riccardo; Torquati, Ilaria; Scortichini, Mirko; Rinaldo, Serena; Fernicola, Silvia; Giardina, Giorgio; Paiardini, Alessandro; Leoni, Livia; Rampioni, Giordano; Messina, Marco; Cutruzzolà, Francesca; Cappellacci, Loredana | Poster atto convegno su volume | |
Design, synthesis and biological evaluation of novel inhibitors of key enzymes in c-di-GMP metabolism as potential antibiofilm drugs | 20-mar-2015 | Torquati, Ilaria | Doctoral Thesis | |
Design, synthesis and biological evaluation of novel inhibitors of NAD kinase | 1-gen-2012 | Torquati, Ilaria; Vita, Patrizia; Petrelli, Riccardo; Di Stefano, M; Cappellacci, Loredana | Contributo in atto di convegno su volume | |
Design, Synthesis, and Anticancer Activity of Novel Pyridyl and Aryl Hydrazones | 1-gen-2015 | Petrelli, Riccardo; Torquati, Ilaria; Scortichini, Mirko; Grisogani, Federica; Angeloni, Yara; Girotti, Francesca; Brusseel, Marieke; Nabissi, Massimo; Santoni, Giorgio; Hofer, Anders; Ranjbarian, Farahnaz; Cappellacci, Loredana | Poster atto convegno su volume | |
Exploring the Role of N6‐Substituents in Potent Dual Acting 5'‐C‐Ethyltetrazolyladenosine Derivatives: Synthesis, Binding, Functional Assays, and Antinociceptive Effects in Mice | 1-gen-2017 | Petrelli, Riccardo; Scortichini, Mirko; Kachler, Sonja; Boccella, Serena; Cerchia, Carmen; Torquati, Ilaria; DEL BELLO, Fabio; Salvemini, Daniela; Novellino, Ettore; Luongo, Livio; Maione, Sabatino; A Jacobson, Kenneth; Lavecchia, Antonio; Klotz, Karl-Norbert; Cappellacci, Loredana | Articolo | |
From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine | 1-gen-2014 | Petrelli, Riccardo; Maria, Meli; Vita, Patrizia; Torquati, Ilaria; Arianna, Ferro; Munender, Vodnala; Natale, D’Alessandro; Manlio, Tolomeo; DEL BELLO, Fabio; Praveen, Kusumanchi; Palmarisa, Franchetti; Mario, Grifantini; Hiremagalur N., Jayaram; Anders, Hofer; Cappellacci, Loredana | Articolo | |
IDENTIFICATION OF MOLECULES THAT INHIBITS c-di-GMP SYNTHESIS TO TARGET BIOFILM FORMATION | 1-gen-2014 | Fernicola, S; Paiardini, A; Rinaldo, S; Torquati, Ilaria; Petrelli, Riccardo; Cappellacci, Loredana; Cutruzzolà, F. | Poster atto convegno su volume | |
N6/5’-DISUBSTITUTED ADENOSINE AND 2-CHLORO-ADENOSINE DERIVATIVES AS POTENT AND SELECTIVE A1 ADENOSINE RECEPTOR AGONISTS: SYNTHESIS, BINDING ASSAYS AND ANTINOCICEPTIVE ACTIVITY IN MICE | 1-gen-2013 | Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; L., Luongo; F., Guida; M., De Chiaro; K. N., Klotz; S., Kachler; P., Franchetti; S., Maione; M., Grifantini; Cappellacci, Loredana | Poster atto convegno su volume | |
N6/5’-DISUBSTITUTED ADENOSINE AND 2-CHLORO-ADENOSINE DERIVATIVES AS POTENT AND SELECTIVE A1 ADENOSINE RECEPTOR AGONISTS: SYNTHESIS, BINDING ASSAYS AND ANTINOCICEPTIVE ACTIVITY IN MICE | 1-gen-2014 | Petrelli, Riccardo; Vita, Patrizia; Torquati, Ilaria; Livio, Luongo; Francesca, Guida; Maria De, Chiaro; Karl Norbert, Klotz; Sonja, Kachler; Palmarisa, Franchetti; Sabatino, Maione; Mario, Grifantini; Cappellacci, Loredana | Poster atto convegno su rivista | |
NOVEL 2-SUBSTITUTED 2’/3’-C-METHYL-ADENOSINE DERIVATIVES: SYNTHESIS AND BIOLOGICAL EVALUATION AGAINST TRYPANOSOMA BRUCEI | 1-gen-2013 | Petrelli, Riccardo; Torquati, Ilaria; Vita, Patrizia; L., Boccoli; A., Hofer; M., Vodnala; P., Franchetti; M., Grifantini; Cappellacci, Loredana | Poster atto convegno su volume | |
Novel dual acting 5’-C-ethyl-tetrazolyl-N6-substituted adenosine derivatives: synthesis and biological evaluation | 1-gen-2015 | Petrelli, Riccardo; Torquati, Ilaria; Livio, Luongo; Sonja, Kachler; Angeloni, Yara; Marieke, Brusseel; Antonio, Lavecchia; Sabatino, Maione; Karl Norbert, Klotz; Cappellacci, Loredana | Poster atto convegno su volume |